Abstract Number: 2257 • ACR/ARHP Annual Meeting 2016
Regulation of Mitochondrial Proton Gradient Is Critical for NLRP3 Inflammasome Activation
Background/Purpose: Self-activating mutations in NLRP3 cause a spectrum of autoinflammatory diseases known as cryopyrin-associated periodic syndromes (CAPS). NLRP3 is a key component of a multiprotein…
ACR Meeting Abstracts