Abstracts tagged "miRNA"

Abstract Number: 1943 • 2019 ACR/ARP Annual Meeting
The Emerging Regulatory Function of microRNA146a in Bone Biology and Osteoporosis
Victoria Saferding¹, Melanie Hofmann ², Julia S. Brunner ², Mihaela F. Militaru ², Antonia Puchner ², Silvia Hayer ², Melanie Timmen ³, Richard Stange ³, Josef Smolen ² and Stephan Blüml ⁴, ¹Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, ²Medical University of Vienna, Vienna, Austria, ³University Hospital Muenster, Muenster, Germany, ⁴Medical University of Vienna, Vienna
Background/Purpose: Micro RNAs (miRNAs) play a crucial role in the regulation of bone metabolism. MiR-146a, an important anti-inflammatory miRNA, was found to negatively impact osteogenesis…
Abstract Number: 2487 • 2019 ACR/ARP Annual Meeting
Identification of Circulating MicroRNA Signatures in Patients with Psoriasis and Psoriatic Arthritis to Develop Novel Strategies for Early Diagnosis of a Bone and Joint Involvement
Judith Haschka¹, David Simon ², Sara Bayat ³, Arnd Kleyer ³, Eleni Kampylafka ³, Axel Hueber ⁴, Christian Muschitz ⁵, Susanna Skalicky ⁶, Matthias Hackl ⁶, Heinrich Resch ¹, Georg Schett ⁷, Roland Kocijan ⁸ and Jürgen Rech ⁹, ¹Karl Landsteiner Institute for Gastroenterology and Rheumatology, St. Vincent Hospital Vienna, II Medical Department, Vienna, Austria, ²Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany, ³Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany, ⁴Sozialstiftung Bamberg, Klinikum Bamberg, Section Rheumatology, Bamberg, Germany, Bamberg, Germany, ⁵St. Vincent Hospital Vienna, II Medical Department, VINFORCE Study Group, Vienna, Austria, ⁶TAmiRNA GmbH, Vienna, Austria, Vienna, Austria, ⁷Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany, ⁸Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria, ⁹Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: MicroRNAs (miRNAs) are small non-coding RNAs which are regulating physiologic and pathological processes. In numerous diseases specific miRNA signatures have been identified and can…

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