Abstracts tagged "Migration inhibitory factor (MIF)"

Abstract Number: 875 • 2012 ACR/ARHP Annual Meeting
Discovery of Pharmacologic MIF Antagonists by Structure-Based Molecular Design
William L. Jorgensen¹, Alissa A. Hare¹, Zoe Cournia¹, Sunilkumar Gandavadi¹, Xin Du¹, Lin Leng¹ and Richard J. Bucala², ¹Yale University, New Haven, CT, ²Rheum/Dept of Int Med, Yale University School of Med, New Haven, CT
Background/Purpose: Cytokine inhibition is becoming a mainstay for the therapy of autoimmunity but current antibody-based approaches remain limited by high cost, parenteral administration, and anti-idiotype…

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Abstracts tagged "Migration inhibitory factor (MIF)"

Discovery of Pharmacologic MIF Antagonists by Structure-Based Molecular Design