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Abstracts tagged "MicroRNA and systemic lupus erythematosus (SLE)"

  • Abstract Number: 2870 • ACR/ARHP Annual Meeting 2016

    Overexpression of EZH2 at the microRNA-142 Regulatory Region Contributes to Down-Regulation of microRNA-142-3p/5p in Systemic Lupus Erythematosus

    Shu Ding1, Qing Zhang2, Shuangyan Luo2, Lina Tan1, Hai Long3, Ming Zhao3, Yunsheng Liang2 and Qianjin Lu3, 1Department of Dermatology, The Third Xiangya Hospital of Central South University, Changsha, China, 2Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, China, 3The Second Xiangya Hospital of Central South University, Changsha, China

    Background/Purpose: Recently, our group has demonstrated that decreased microRNA-142-3p/5p (miR-142-3p/5p) which contributes to T cell overactivation and B cell hyperstimulation plays an essential role in…

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