Abstracts tagged "MicroRNA and rheumatoid arthritis (RA)"

Abstract Number: 1368 • 2017 ACR/ARHP Annual Meeting
Small RNA Sequencing Identifies Plasma microRNA Panel for Rheumatoid Arthritis Diagnosis
Michelle J. Ormseth¹, Joseph F. Solus², Quanhu Sheng², Yan Guo², Fei Ye², Ryan Allen², Kasey Vickers² and C Michael Stein², ¹Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Small noncoding RNAs (sRNAs), such as microRNAs (miRNAs), are regulators of biological processes and serve as important biomarkers of disease. Most previous plasma sRNA…
Abstract Number: 499 • 2016 ACR/ARHP Annual Meeting
High Levels of Mir-451a Differentiate Patients at Risk of Developing RA from Healthy Controls
Klára Prajzlerová¹, Veronika Hrušková², Petra Hánová¹, Heřman F Mann¹, Karel Pavelka¹, Jiří Vencovský³, Ladislav Šenolt¹ and Mária Filková¹, ¹Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, ²Institute of Rheumatology and Department of Rheumatology, Faculty of Science, Charles University in Prague, Prague, Czech Republic, ³Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
Background/Purpose: Individuals with clinically suspect arthralgia (CSA) with positivity of antibodies to citrullinated protein antigens (ACPA) have articular symptoms without clinical signs of arthritis. CSA…
Abstract Number: 3106 • 2015 ACR/ARHP Annual Meeting
Regulation of ASK1 Expression By microRNA-17 and Their Correlation with Rheumatoid Arthritis Pathogenesis
Nahid Akhtar and Salahuddin Ahmed, Department of Pharmaceutical Sciences, Washington State University College of Pharmacy, Spokane, WA
Background/Purpose: Aberrant expression of microRNAs (miRs) has shown to be critical for the pathogenesis of rheumatoid arthritis (RA). Apoptosis signal regulating kinase-1 (ASK1), a member…
Abstract Number: 3153 • 2015 ACR/ARHP Annual Meeting
Microrna-155/PU.1 Axis As an Epigenetic Regulator of B-Cells in Rheumatoid Arthritis
Stefano Alivernini¹, Barbara Tolusso¹, Mariola Kurowska-Stolarska², Roberta Benvenuto³, Antonella Mangoni³, Silvia Canestri¹, Luca Petricca¹, Anna Laura Fedele¹, Maria Rita Gigante¹, Clara Di Mario¹, Elisa Gremese¹, Iain B. McInnes² and Gianfranco Ferraccioli¹, ¹Division of Rheumatology, Institute of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom, ³Division of Pathology - Catholic University of the Sacred Heart, Rome, Italy
Background/Purpose: MicroRNA-155(miR-155) has been shown to be a key regulator of B cell biology by PU.1 regulation. However, the role of miR-155 in the activation…
Abstract Number: 999 • 2014 ACR/ARHP Annual Meeting
Microrna-155 As an Epigenetic Regulator of B-Cell Activation in Rheumatoid Arthritis: In Vivo and in Vitro Evidences
Stefano Alivernini¹, Barbara Tolusso¹, Silvia Canestri¹, Luca Petricca¹, Clara Di Mario², Elisa Gremese¹ and Gianfranco Ferraccioli¹, ¹Division of Rheumatology, Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy, ²Division of Pathology, Catholic University of the Sacred Heart, Rome, Italy
Background/Purpose: MicroRNAs (miRs) are a novel class of post-transcriptional regulators. miR-155 was shown to be a regulator of B cell biology in haematological diseases as…

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