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Abstracts tagged "MicroRNA and innate immunity"

  • Abstract Number: 2026 • ACR/ARP Annual Meeting 2019

    MicroRNA-27a Can Contribute to Interferon Signatures in Systemic Lupus Erythematosus via the Suppression of Tripartite Motif-containing Protein 27

    Daiga Kishimoto1, Ryusuke Yoshimi 1, Yosuke Kunishita 1, Yumiko Sugiyama 2, Takaaki Komiya 1, Natsuki Sakurai 3, Reikou Kamiyama 1, Yohei Kirino 4 and Hideaki Nakajima 4, 1Department of Stem Cell and Immune Regulation / Yokohama City University Graduate School of Medicine, Yokohama, Japan, 2Department of Rheumatic Diseases / Yokohama City University Medical Center, Yokohama, Japan, 3Department of Stem Cell and Immune Regulation / Yokohama City University Graduate School of Medicine, Yokohama City, Japan, 4Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan

    Background/Purpose: Type Ⅰ interferons (IFN) contribute to antiviral innate immune responses. Upon viral infection, pattern recognition receptors trigger TANK-binding kinase 1 (TBK1) activation and lead…
  • Abstract Number: 1162 • ACR/ARHP Annual Meeting 2013

    The Role Of Microrna 155 In Innate Immunity and Arthritis

    Antonia Puchner1, Victoria Saferding2, Eliana Goncalves-Alves3, Josef S. Smolen4, Kurt Redlich5 and Stephan Blueml6, 1Department of Rheumatology, Medical University of Vienna, Vienna, Austria, 2Rheumatology, Medical University of Vienna, Vienna, Austria, 3rheumatology, Medical University of Vienna, Vienna, Austria, 4Medical University of Vienna, Vienna, Austria, 5Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 6Division of Rheumatology, Medical University of Vienna, Vienna, Austria

    Background/Purpose: MicroRNA 155 (miR155) has been demonstrated to be essential for the development of collagen induced arthritis by controlling the generation of autoreactive T and…

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