Abstracts tagged "MicroRNA and innate immunity"

Abstract Number: 2026 • 2019 ACR/ARP Annual Meeting
MicroRNA-27a Can Contribute to Interferon Signatures in Systemic Lupus Erythematosus via the Suppression of Tripartite Motif-containing Protein 27
Daiga Kishimoto¹, Ryusuke Yoshimi ¹, Yosuke Kunishita ¹, Yumiko Sugiyama ², Takaaki Komiya ¹, Natsuki Sakurai ³, Reikou Kamiyama ¹, Yohei Kirino ⁴ and Hideaki Nakajima ⁴, ¹Department of Stem Cell and Immune Regulation / Yokohama City University Graduate School of Medicine, Yokohama, Japan, ²Department of Rheumatic Diseases / Yokohama City University Medical Center, Yokohama, Japan, ³Department of Stem Cell and Immune Regulation / Yokohama City University Graduate School of Medicine, Yokohama City, Japan, ⁴Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan
Background/Purpose: Type Ⅰ interferons (IFN) contribute to antiviral innate immune responses. Upon viral infection, pattern recognition receptors trigger TANK-binding kinase 1 (TBK1) activation and lead…
Abstract Number: 1162 • 2013 ACR/ARHP Annual Meeting
The Role Of Microrna 155 In Innate Immunity and Arthritis
Antonia Puchner¹, Victoria Saferding², Eliana Goncalves-Alves³, Josef S. Smolen⁴, Kurt Redlich⁵ and Stephan Blueml⁶, ¹Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Rheumatology, Medical University of Vienna, Vienna, Austria, ³rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Medical University of Vienna, Vienna, Austria, ⁵Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁶Division of Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: MicroRNA 155 (miR155) has been demonstrated to be essential for the development of collagen induced arthritis by controlling the generation of autoreactive T and…

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