ACR Meeting Abstracts
Abstract Number: 934 • ACR/ARHP Annual Meeting 2015
Pierre Cunin1, Loka Penke2, Jonathan Thon3, Paul A. Monach4, Tatiana Jones5, Mary Chen2, Yoichiro Iwakura6, Jerry Ware7, Michael Gurish2, Joseph Italiano3, Eric Boilard8 and Peter A. Nigrovic2,9, 1Rheumatology, Immunology and Allergy, Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 2Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 3Department of Medicine, Hematology Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4Rheumatology, Boston University School of Medicine, Boston, MA, 5Department of Clinical Laboratory and Nutritional Science, University of Massachusetts Lowell, Lowel, MA, 6Center for Experimental Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan, 7Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, 8Centre de Recherche en Rhumatologie et Immunologie, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Faculté de Médecine de l’Université Laval, Quebec, QC, Canada, 9Department of Medicine, Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Mice bearing mutations affecting Kit (stem cell factor receptor) exhibit multiple hematologic phenotypes, including mast cell deficiency, and have been used to assess the…