Abstracts tagged "microparticles and platelets"

Abstract Number: 934 • 2015 ACR/ARHP Annual Meeting
Platelet-Independent Role of Megakaryocytes in Antibody-Mediated Murine Arthritis
Pierre Cunin¹, Loka Penke², Jonathan Thon³, Paul A. Monach⁴, Tatiana Jones⁵, Mary Chen², Yoichiro Iwakura⁶, Jerry Ware⁷, Michael Gurish², Joseph Italiano³, Eric Boilard⁸ and Peter A. Nigrovic^2,9, ¹Rheumatology, Immunology and Allergy, Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ²Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ³Department of Medicine, Hematology Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Rheumatology, Boston University School of Medicine, Boston, MA, ⁵Department of Clinical Laboratory and Nutritional Science, University of Massachusetts Lowell, Lowel, MA, ⁶Center for Experimental Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan, ⁷Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, ⁸Centre de Recherche en Rhumatologie et Immunologie, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Faculté de Médecine de l’Université Laval, Quebec, QC, Canada, ⁹Department of Medicine, Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Mice bearing mutations affecting Kit (stem cell factor receptor) exhibit multiple hematologic phenotypes, including mast cell deficiency, and have been used to assess the…

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