Abstracts tagged "microparticles and neutrophils"

Abstract Number: 1023 • 2019 ACR/ARP Annual Meeting
Neutrophils Are an Important Source of Microparticles in Lupus and Asymptomatic ANA+ Individuals
Carolina Muñoz-Grajales¹, Dennisse Bonilla ², Earl D. Silverman ³, Sindhu Johnson ⁴, Arthur Bookman ⁵, Zahi Touma ², Zareen Ahmad ⁶, Linda Hiraki ⁷ and Joan Wither ⁸, ¹University of Toronto, Toronto, Canada, ²University Health Network, University of Toronto, Toronto, ON, Canada, ³Division of Rheumatology, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Translational Medicine, Research Institute, The Hospital for Sick Children, Toronto, Canada, ⁴Toronto Scleroderma Program, Department of Medicine, Toronto Western and Mount Sinai Hospitals, University of Toronto, Toronto, Canada, Toronto, Canada, ⁵University Health Network - Toronto Western Hospital, Toronto, Canada, ⁶Mount Sinai Hospital, Toronto, Canada, ⁷The Hospital for Sick Children, Toronto, Canada, ⁸University Health Network, Krembil Research Institute, Toronto, ON, Canada
Background/Purpose: Apoptotic microparticles (MPs) in the circulation of systemic lupus erythematosus (SLE) patients are enriched for nucleic acids and complexed with IgG (MP-IC), as compared…

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