Abstracts tagged "Microchimerism"

Abstract Number: 2431 • 2017 ACR/ARHP Annual Meeting
Acquisition of Protective Alleles in Women with Rheumatoid Arthritis through Microchimerism
Sami B. Kanaan¹, Vijayakrishna K. Gadi^1,2, Alexandra M. Forsyth¹, Christine Luu¹, Tessa Aydelotte¹ and J. Lee Nelson^1,3, ¹Clinical Research Division, Fred Hutchinson Cancer Research Center, SEATTLE, WA, ²Division of Oncology, University of Washington, SEATTLE, WA, ³Division of Rheumatology, University of Washington, SEATTLE, WA
Background/Purpose: As in many autoimmune diseases, rheumatoid arthritis (RA) has a female predominance and strong genetic susceptibility from the HLA region. The shared epitope (SE),…
Abstract Number: 2999 • 2015 ACR/ARHP Annual Meeting
Maternal Microchimerism Is Increased in Multiple Cellular Subsets of Patients with Systemic Sclerosis Compared to Healthy Controls
Sami B. Kanaan¹, Whitney Harrington^2,3, Laurence S. Loubiere⁴, Tessa M. Aydelotte¹ and J. Lee Nelson^1,5, ¹Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, ²Seattle Children's Hospital, Seattle, WA, ³Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, ⁴University of Birmingham, Birmingham, United Kingdom, ⁵University of Washington, Seattle, WA
Background/Purpose: Microchimerism (Mc) is naturally acquired through bi-directional exchange of small amounts of cells or DNA between mother and fetus during pregnancy. Higher amounts of…

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