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Abstracts tagged "microbiome and osteoarthritis"

  • Abstract Number: 1358 • ACR/ARHP Annual Meeting 2018

    The Association of Microbial Translocation and WOMAC Function in Patients with Knee Osteoarthritis

    Sunghye Kim1, Richard Loeser2, Dennis Ang3 and Stephen P. Messier4, 1Medicine, Wake Forest School of Medicine, Winston Salem, NC, 2Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Wake Forest University School of Medicine, Winston-Salem, NC, 4Department of Health and Exerc, Wake Forest University, Winston-Salem, NC

    Background/Purpose: Osteoarthritis (OA) affects 33.6% of population ≥65. Knee OA (KOA) is the most prevalent OA and it is one of five leading causes of…
  • Abstract Number: 2005 • ACR/ARHP Annual Meeting 2018

    Identification of a Human Cartilage Microbial DNA Signature and Characterization of Distinct Microbiome Profiles Associated with Osteoarthritis

    Chris Dunn1,2, Cassandra Velasco1,3, Alexander Rivas4, Madison Andrews3,5, Paul Jacob6 and Matlock A. Jeffries2,7, 1Rheumatology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Oklahoma Medical Research Foundation, Oklahoma City, OK, 4University of Arkansas for Medical Sciences, Little Rock, AR, 5Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 6Oklahoma Sport Science and Orthopedics, Oklahoma City, OK, 7Department of Medicine, Division of Rheumatology, Immunology, and Allergy, University of Oklahoma Health Sciences Center, Oklahoma City, OK

    Background/Purpose: Osteoarthritis (OA) is both the most common form of arthritis and a leading cause of chronic disability. Bacterial products, including lipopolysaccharide (LPS), have been…
  • Abstract Number: 2006 • ACR/ARHP Annual Meeting 2018

    Murine Ear Wound Cartilage Superhealer Trait Is Associated with Gut Microbiota Changes and Is Transferable to Non-Healer Mice By Gut Microbiome Transplant

    Chris Dunn1,2, Cassandra Velasco1,3, Madison Andrews3,4, Alexander Rivas5 and Matlock A. Jeffries2,6, 1Rheumatology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 5University of Arkansas for Medical Sciences, Little Rock, AR, 6Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK

    Background/Purpose: MRL/MpJ mice are substantially protected from developing post-traumatic osteoarthritis (OA), a trait with strong correlation to the ability to heal ear wounds. Previous studies…

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