Abstracts tagged "methylation and systemic sclerosis"

Abstract Number: 807 • ACR/ARHP Annual Meeting 2018
The Effects of DNA Methylation on Differential Expression in Dermal Fibroblasts from African-American Patients with Systemic Sclerosis
DeAnna Baker Frost¹, Willian da Silveira², Ilia Atanelishvili³, Robert C. Wilson⁴, E. Starr Hazard², Jim C. Oates⁵, Galina S. Bogatkevich³, Carol A. Feghali-Bostwick⁶, Gary Hardiman⁷ and Paula S. Ramos⁸, ¹Medicine, Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ²Center for Genomic Medicine, Medical University of South Carolina, Charleston, SC, ³Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC, ⁴Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, ⁵Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC, ⁶Department of Medicine, Medical University of South Carolina, Division of Rheumatology and Immunology, Charleston, SC, ⁷Department of Medicine, Medical University of South Carolina, Charleston, SC, ⁸Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC
Background/Purpose: The etiology and reasons underlying the ethnic disparities in systemic sclerosis (SSc) remain unknown. African-Americans (AA) are disproportionally affected by SSc, yet dramatically underrepresented…