Abstracts tagged "methotrexate (MTX) and vitamins"

Abstract Number: 2597 • 2012 ACR/ARHP Annual Meeting
Degree of Initial Intracellular Folate Depletion May Predict Methotrexate Response in Juvenile Idiopathic Arthritis
Leon van Haandel¹, Ryan S. Funk¹, Maria F. Ibarra², Mark F. Hoeltzel³, Andrew Lasky⁴, Daisy Dai⁵, Rodger Gaedigk¹, J. Steven Leeder⁶ and Mara L Becker⁵, ¹Clinical Pharmacology and Medical Toxicology, Children's Mercy Hospital, Kansas City, MO, ²Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, ³Rheumatology Section, Children's Mercy Hospital, Kansas City, MO, ⁴Pediatrics Rheumatology, Children's Mercy Hospital, Kansas City, MO, ⁵Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, ⁶Individualized medicine, Children's Mercy Hospital, Kansas City, MO
Background/Purpose: Despite widespread use, there are no predictors of methotrexate (MTX) response or toxicity. The objective of this study is to test the hypothesis that…