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Abstracts tagged "methotrexate (MTX) and vitamins"

  • Abstract Number: 2597 • 2012 ACR/ARHP Annual Meeting

    Degree of Initial Intracellular Folate Depletion May Predict Methotrexate Response in Juvenile Idiopathic Arthritis

    Leon van Haandel1, Ryan S. Funk1, Maria F. Ibarra2, Mark F. Hoeltzel3, Andrew Lasky4, Daisy Dai5, Rodger Gaedigk1, J. Steven Leeder6 and Mara L Becker5, 1Clinical Pharmacology and Medical Toxicology, Children's Mercy Hospital, Kansas City, MO, 2Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, 3Rheumatology Section, Children's Mercy Hospital, Kansas City, MO, 4Pediatrics Rheumatology, Children's Mercy Hospital, Kansas City, MO, 5Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, 6Individualized medicine, Children's Mercy Hospital, Kansas City, MO

    Background/Purpose: Despite widespread use, there are no predictors of methotrexate (MTX) response or toxicity.  The objective of this study is to test the hypothesis that…
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