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Abstracts tagged "methotrexate (MTX) and rheumatic disease"

  • Abstract Number: 2267 • ACR/ARHP Annual Meeting 2016

    AMP-Activated Protein Kinase: A  Target for Methotrexate in Macrophages

    Cornelia Cudrici1, Martin Pelletier2 and Richard M. Siegel3, 1NIAMS, Immunoregulation Section, Autoimmunity Branch, Bethesda, MD, 2Infectious and immune diseases Centre Hospitalier de l'Université Laval (CHUL) Québec, Québec, QC, Canada, 3National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD

    Background/Purpose: Methotrexate (MTX) remains a cornerstone of treatment in multiple forms of inflammatory arthritis, lupus and vasculitis. The anti-inflammatory effects of MTX are more likely…

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