Abstracts tagged "metabolism and rheumatic disease"

Abstract Number: 883 • ACR/ARHP Annual Meeting 2015
Evaluation of Thiopurine Metabolites Monitoring in Patients Treated with Azathioprine for Rheumatic Diseases
Aurélie Chapdelaine¹, Maxime Doré², Yves Troyanov³ and Anne-Marie Mansour¹, ¹Internal Medicine, Université de Montréal, Montréal, QC, Canada, ²Pharmacy, Université de Montréal, Montréal, QC, Canada, ³Rheumatology, Université de Montréal, Montréal, QC, Canada
Background/Purpose: The thiopurine azathioprine (AZA) is an inactive pro-drug that undergoes complex metabolic transformations leading to the formation of 6-thioguanine nucleotide (6-TGN), the active metabolite,…