Abstracts tagged "metabolism and metabolomics"

Abstract Number: 38 • ACR/ARHP Annual Meeting 2017
Cytokine Production By CpG-Activated B Cells Require Glutaminolysis to Drive mTOR Activation, Aerobic Glycolysis and Mitochondrial Respiration
Matthew Cheung¹, Dongyue Huang¹, Emily Liu², Jennifer Ra² and Alfred Kim³, ¹Rheumatology, Washington University School of Medicine, Saint Louis, MO, ²IM/Rheumatology, Washington University School of Medicine, Saint Louis, MO, ³IM/Rheumatology, Washington University School of Medicine, St. Louis, MO
Background/Purpose: B cells contribute to disease pathophysiology through several mechanisms, including cytokine secretion. A wide variety of stimuli can activate B cells to produce cytokines…