Abstracts tagged "metabolism and glycolysis"

Abstract Number: 1970 • 2019 ACR/ARP Annual Meeting
Mechanism of Chondroprotective Effects of 4-Methylumbelliferone and 2-Deoxyglucose
Kenya Terabe¹, Nobunori Takahashi ¹, Yoshifumi Ohashi ², Toshihisa Kojima ¹, Naoki Ishiguro ¹, Cheryl Knudson ² and Warren Knudson ², ¹Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan, ²East Carolina University, Greenville
Background/Purpose: We recently reported that the inhibitor of hyaluronan (HA) biosynthesis, 4-methylumbelliferone (4-MU) blocked IL-1β activation of MMP13 mRNA and protein expression in human osteoarthritic…

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Abstracts tagged "metabolism and glycolysis"

Mechanism of Chondroprotective Effects of 4-Methylumbelliferone and 2-Deoxyglucose