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Abstracts tagged "mesenchymal stem cells and therapy"

  • Abstract Number: 346 • ACR/ARHP Annual Meeting 2014

    Treatment of Collagen Induced Artritis with Human Embrionic Stem Cell-Derived Multipotent Mesenchymal Stromal Cells (hESC-MSC)

    Gabriel Criado1, María J. Pérez-Lorenzo1, María Galindo2, Jose L. Pablos2, Pablo Menéndez3 and Elena Gonzalo-Gil4, 1Grupo de Enfermedades Inflamatorias y Autoinmunes, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 2Servicio de Reumatología, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 3Josep Carreras Leukemia Research Insitute, Barcelona, Spain, 4Grupo de Investigación en Enfermedades Inflamatorias y Autoinmunes, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain

    Background/Purpose Inhibition of TGFβ signaling in human Embryonic Stem Cells (hESC) generates mesenchymal stromal cells (hESC-MSC) with osteogenic, adipogenic and chondrogenic potential. These cells have…
  • Abstract Number: 2218 • ACR/ARHP Annual Meeting 2013

    Gingival Stem Cells Suppress Osteoclast Formation and Bone Erosion In CIA Through CD39 Signal

    Song Guo Zheng1, Jian Gu2, Maogeng Chen1 and Yi Shen3, 1Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, 2Medcine, University of Southern California Keck School of Medicine, Los Angeles, CA, 3Medicine, Shanghai East Hospital at Tongji University, Shanghai, China

    Background/Purpose: We recently have reported that human-derived gingival mesenchymal stem cells (GMSC) have strong capacity to suppress immune responses and T cell-mediated collagen-induced arthritis, however,…

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