Abstract Number: 850 • 2018 ACR/ARHP Annual Meeting
Long Term Efficacy of Cartilage Repair Induced By scSOX9 in Situ with Bone Marrow-Derived Mesenchymal Stem Cells
Background/Purpose: Microfracture induces fibrocartilage or fibro-hyaline cartilage both are biomechanically inferior to hyaline cartilage. We reported previously that a super positively charged SOX9 (scSOX9) improved…Abstract Number: 1876 • 2013 ACR/ARHP Annual Meeting
Potential Chondrogenic Biomarkers For Cell-Based Therapy Monitoring In Osteoarthritis
Background/Purpose: Chondrogenesis occurs as a result of mesenchymal stem cells (MSCs) condensation and chondroprogenitor cell differentiation. Following chondrogenesis, the chondrocytes remain as resting cells to…Abstract Number: 66 • 2013 ACR/ARHP Annual Meeting
Follistatin-Like Protein 1 Is An Important Regulator Of Chondrogenesis
Background/Purpose: Chondrocytes play a pivotal role in osteoarthritis (OA) because they are the only cells in the articular cartilage that are responsible for maintenance of…Abstract Number: 78 • 2013 ACR/ARHP Annual Meeting
Norepinephrine (NE) Inhibits Mesenchymal Stem Cell (MSCs) Chondrogenesis By Accelerating Hypertophy – Relevance For Cartilage Regeneration
Background/Purpose: The high potential of mesenchymal stem cells (MSCs) in cartilage regeneration is undoubtful. The presence of MSCs in healthy or arthritic cartilage has also…Abstract Number: 1006 • 2012 ACR/ARHP Annual Meeting
Dynamic Gene Expression of Wnt Signaling Pathway During Osteogenic Stimulation in Vitro of Osteoarthritis Mesenchymal Stem Cells
Background/Purpose: The role of Wnt signalling in Mesenchymal Stem Cell (MSC) fate is still unclarified. Both, canonical and non-canonical pathways have been implicated in differentiation…Abstract Number: 48 • 2012 ACR/ARHP Annual Meeting
Tissue Engineering for Articular Cartilage Repair, Culturing Bone Marrow Mesenchymal Stem Cells On Collagen and Heparan Sulphate Scaffolds
Background/Purpose: The aim of this study was to evaluate the chondrogenic potential of bone marrow mesenchymal stem cells (BM-MSCs) grown on type I collagen and…Abstract Number: 50 • 2012 ACR/ARHP Annual Meeting
Human Chondrocyte Dedifferentiation Is Accompagnied by CD105 Endoglin Expression, ALK-1/Smad1/5 Phosphorylation and Leptin Production – Stimulation by Prednisolone and Aldosterone Through the Glucocorticoid Receptor
Background/Purpose: Leptin, mainly produced by the adipose tissue including fat neighboring the joint, is considered as pro-inflammatory in osteoarthritis (OA). Normal cartilage does not…Abstract Number: 7 • 2012 ACR/ARHP Annual Meeting
Lamin A Deregulation in Human Mesenchymal Stem Cells Promotes an Impairment in Their Chondrogenic Potential and Imbalance in Their Response to Oxidative Stress
Background/Purpose: Previous work by our group and others indicated that an accumulation of lamin A (LMNA) was associated with the osteoarthritis (OA) chondrocyte phenotype. Mutations…Abstract Number: 22 • 2012 ACR/ARHP Annual Meeting
Protective Properties of Conditioned Media From Adipose Stem Cells On Osteoarthritic Chondrocytes
Background/Purpose: Adipose-derived mesenchymal stem cells (ASC) exhibit a high potential for cell therapy and they might also act as a cellular source for supplying soluble…