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Abstracts tagged "memory"

  • Abstract Number: 166 • Pediatric Rheumatology Symposium 2020

    Resident Memory T Cells in Human RA Synovium Display Restricted TCR Clones

    Margaret Chang1, Anais Levescot 2, Nathan Nelson-Maney 3, Rachel Blaustein 4, Kellen Winden 1, Allyn Morris 4, Spoorthi Balu 4, Alexandra Wactor 4, Kevin Wei 5, Lauren Henderson 6, Rachael Clark 4, Deepak Rao 4, Robert Fuhlbrigge 7 and Peter Nigrovic 8, 1Boston Children's Hospital, Boston, 2Boston, 3, 4Brigham and Women's Hospital, Boston, 5BWH, Boston, 6Boston Children's Hospital, Watertown, Massachusetts, 7University of Colorado, Aurora, 8Boston Children's Hospital, Boston, Massachusetts

    Background/Purpose: Resident memory T cells (TRM) are site-specific memory T cells that take up long-term residence in peripheral tissues and aid in pathogen defense. Dysregulated…
  • Abstract Number: 114 • ACR/ARP Annual Meeting 2019

    Persistent Synovial Resident Memory T Cells Mediate Arthritis Flares

    Margaret Chang1, Anaïs Levescot 2, Rachel Blaustein 2, Nathan Nelson-Maney 2, Allyn Morris 2, Robert Fuhlbrigge 3 and Peter Nigrovic 4, 1Division of Immunology, Boston Children's Hospital, Boston, 2Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, 3Department of Rheumatology, Children’s Hospital Colorado, Denver, CO, 4Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA ; Department of Medicine, Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA., Boston

    Background/Purpose: Resident memory T cells (TRM) are site-specific memory T cells that take up long-term residence in peripheral tissues and aid in pathogen defense. However,…
  • Abstract Number: 563 • ACR/ARHP Annual Meeting 2016

    Factors Associated with Cognitive Impairment in Korean Adults with Rheumatoid Arthritis

    So Young Shin1, Joo Hyun Lee2 and Bo Young Yoon3, 1Department of Nursing, Inje University, College of Medicine, Department of Nursing, Busan, Korea, The Republic of, 2Rheumatology/Internal medicine, Inje University Ilsan Paik Hospital, Goyang, Korea, The Republic of, 3Rheumatology/Internal medicine, Inje Iniversity Ilsan Paik Hospital, Goyang, Korea, The Republic of

    Background/Purpose:  For persons with chronic diseases such as rheumatoid arthritis (RA), intact cognitive function is crucial for performing main daily activities and adhering to self-management…
  • Abstract Number: 1058 • ACR/ARHP Annual Meeting 2016

    Adjustment Profiles Comprising Objective and Subjective Measures in Fibromyalgia Patients

    Fernando Estévez-López1,2, Inmaculada C Álvarez Gallardo1, Víctor Segura-Jiménez1,3, Milkana Borges-Cosic1, Manuel Pulido-Martos4, Ana Carbonell-Baeza3, Virginia A Aparicio1,5, Rinie Geenen2 and Manuel Delgado-Fernández1, 1University of Granada, Granada, Spain, 2Utrecht University, Utrecht, Netherlands, 3University of Cádiz, Cádiz, Spain, 4University of Jaén, Jaén, Spain, 5VU University Medical Care, Amsterdam, Netherlands

    Background/Purpose: Only one-third of FM patients obtain benefits after receiving one of the available therapy modalities. Insights into the heterogeneous picture of FM might improve…
  • Abstract Number: 2644 • ACR/ARHP Annual Meeting 2012

    Functional Magnetic Resonance Imaging of Working Memory in Fibromyalgia: Support for a “Competing Demands” Theory of Cognitive Function in Chronic Pain

    Anson E. Kairys1, Gabriela Ramirez1, Eric Ichesco2, Johnson P. Hampson2, Richard E. Harris2, Daniel J. Clauw3, Tobias Schmidt-Wilcke2 and Jennifer M. Glass4, 1Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, 2Anesthesiology, University of Michigan, Ann Arbor, MI, 3Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, 4Psychiatry, University of Michigan, Ann Arbor, MI

    Background/Purpose: The primary symptom of fibromyalgia (FM) is chronic widespread pain; however, patients report additional symptoms including decreased concentration and memory. Deficits are seen mainly…
  • Abstract Number: 1449 • ACR/ARHP Annual Meeting 2012

    Numbers of Splenic Long-Lived Plasma Cells in Autoimmune and Pre-Autoimmune Lupus Mice Are Linked to a Hyper-Responsive Variant of the Thrombopoietin Receptor and Enhanced Megakaryopoiesis

    Oliver Winter1, Katrin Moser2, Rudolf A. Manz3 and Falk Hiepe4, 1Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany, 2German Arthritis Research Center (DRFZ Berlin), Berlin, Germany, 3Institute for Systemic Inflammation Research (ISEF), University of Lübeck, Lübeck, Germany, 4Med. Klinik m. Sp. Rheumatologie und klin. Immunologie, Charité University Hospital Berlin, Berlin, Germany

    Background/Purpose: Autoantibodies contribute to the pathogenesis of the autoimmune disease Systemic Lupus Erythematosus (SLE) by stimulating the immune response. Further, deposits of immune complexes in…

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