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Abstracts tagged "mechanisms and systemic lupus erythematosus (SLE)"

  • Abstract Number: 2725 • ACR/ARHP Annual Meeting 2013

    Regulation Of Aberrant CD4 T Cell Activation By Suppressor Of Cytokine Signaling-1 (SOCS1) Mimetic Peptide, Has Relevance To Human Systemic Lupus Erythematosus

    Tenisha Wilson1, Cristina Armbruster2, Simone Bedoya2, Howard M. Johnson2, Westley H. Reeves3, Yi Li4, Ying Yi Zheng5, Laurence Morel6 and Joseph Larkin III2, 1Division of Rheumatology & Clinical Immunology, University of Florida, Gainesville, FL, 2Microbiology and Cell Science, University of Florida, Gainesville, FL, 3Rheumatology & Clinical Imm, University of Florida, Gainesville, FL, 4Medicine, University of Florida, Gainesville, FL, 5Pathology, University of Florida, Gainesville, FL, 6Pathology/Immunology/Lab Medical, University of Florida, Gainesville, FL

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease, mediated by aberrantly activated CD4 T cells.  Notably, suppressor of cytokine signaling-1 (SOCS1) regulates CD4 T…

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