Abstracts tagged "MDA"

Abstract Number: 1532 • 2019 ACR/ARP Annual Meeting
Withdrawal of Ixekizumab Results in Loss of Efficacy in Multiple Clinical Domains in Patients with Psoriatic Arthritis Who Had Achieved Minimal Disease Activity: Results from the SPIRIT-P3 Study
Laura Coates¹, Sreekumar Pillai ², Matthew M. Hufford ², Denise Alves ², So Young Park ², Gaia Gallo ², Beilei Wu ³, Ivo Valter ⁴, Hasan Tahir ⁵, Vinod Chandran ⁶, Arthur Kavanaugh ⁷ and Philip Mease ⁸, ¹University of Oxford, Oxford, United Kingdom, ²Eli Lilly and Company, Indianapolis, IN, ³GCE Solutions Inc., Bloomington, IL, ⁴Center for Clinical and Basic Research, Tallinn, Estonia, ⁵Department of Rheumatology, Whipps Cross University Hospital, London, United Kingdom, ⁶Division of Rheumatology, University of Toronto, Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁷University of California, San Diego School of Medicine, La Jolla, CA, ⁸Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA
Background/Purpose: Ixekizumab (IXE), a high affinity monoclonal antibody that selectively targets interleukin-17A, has been demonstrated to improve the signs and symptoms, disease activity, and quality…

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