Abstracts tagged "matrix metalloproteinase (MMP) and synovium"

Abstract Number: 2948 • 2014 ACR/ARHP Annual Meeting
S100 Proteins Induce Canonical Wnt Signaling, Which Causes Increased Expression of MMPs in the Synovium
Martijn H. van den Bosch¹, Arjen B. Blom², R. Pelle Hoek², Rik F. Schelbergen³, Sylvia W. Suen², Anke E. van Erp², Wim B. van den Berg¹, Peter M. van der Kraan¹ and Peter L. van Lent⁴, ¹Experimental Rheumatology (272), Radboud university medical center, Nijmegen, Netherlands, ²Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ³Radboud university medical center, Nijmegen, Netherlands, ⁴Experimental Rheumatology, Experimental Rheumatology, Radboud University, Nijmegen, Netherlands
Background/Purpose: Many osteoarthritis (OA) patients show synovial activation, which is thought to be involved in joint destruction. Previously, we found that the alarmins S100A8 and A9,…

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Abstracts tagged "matrix metalloproteinase (MMP) and synovium"

S100 Proteins Induce Canonical Wnt Signaling, Which Causes Increased Expression of MMPs in the Synovium