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Abstracts tagged "major histocompatibility complex (MHC) and nephritis"

  • Abstract Number: 2468 • ACR/ARHP Annual Meeting 2015

    Antibodies to Histocompatibility Antigens in Juvenile Systemic Lupus Erythematosus Patients

    Ana L Rodríguez-Lozano1, Anne M. Stevens2, Jessica M Foster3, Marisa S. Klein-Gitelman4, Hermine I. Brunner5, Elizabeth Field6, Ann M Reed7 and Karen Onel8, 1Immunology, Instituto Nacional de Pediatria, Mexico City, Mexico, 2Seattle Children's Res Inst, Seattle Children's Hospital, Seattle, WA, 3Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, 4Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 5Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Internal Medicine, University of Iowa, Iowa City, IA, 7Department of Pediatrics, Duke University, Durham, NC, 8Pediatric Rheumatology, Univ of Chicago, Chicago, IL

    Background/Purpose: Microchimerism with HLA mismatched maternal cells can be readily demonstrated in normal individuals and is now established as a normal biological phenomenon.  Pediatric SLE…

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