Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1038 • ACR Convergence 2023
Improved Assessment of Structural Damage in the Spine in Patients with Axial Spondyloarthritis by MRI-based Synthetic CT: A Comparison with Low-dose CT and X-ray
Simone Tromborg Willesen¹, Nora Vladimirova¹, Jakob Moeller², Anna Enevold Fløistrup Hadsbjerg¹, Bimal Mayur Kumar Vora³, Sengul Seven¹, Susanne Juhl Pedersen¹ and Mikkel Østergaard¹, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, ²Herlev-Gentofte Hospital, Herlev, Denmark, ³Singapore General Hospital, Singapore, Singapore
Background/Purpose: Whether a therapy has bone structure-modifying effects in the spine is crucial to determine since this is a prerequisite for a therapy to reduce…
Abstract Number: 1866 • ACR Convergence 2023
MRI Confirms MRE Evidence of Sacroiliitis in Many with Crohn’s Disease: A Prospective Study for the Screening of axSpA in High-risk Populations
Fardina Malik¹, Soterios Gyftopoulos¹, Jordan Axelrad¹, Shannon Chang¹, Simon Hong¹, Maia McAllister², Morayo Kendra Olateru Olagbegi³, Erin Alaia¹, William Walter¹, Accelerating Medicines Partnership Program RA SLE Network⁴, David Hudesman¹ and Jose Scher⁵, ¹NYU Grossman School of Medicine, New York, NY, ²NYU, New York, NY, ³New York University, New York, NY, ⁴Cedars-Sinai Medical Center, Los Angeles, CA, ⁵New York University School of Medicine, New York, NY
Background/Purpose: Sacroiliitis can be detected incidentally on magnetic resonance enterography (MRE) scans in Crohn's disease (CD) patients, obtained for CD assessment during clinical practice. However,…
Abstract Number: 2203 • ACR Convergence 2023
Self-Reported and Physician´s Assessment of Inflammatory Back Pain According to ASAS Criteria: Is It the Same?
Diego Benavent¹, Mar Tapia², Daniel Bernabeu², Victor muley², Chamaida Plasencia-Rodríguez³, Alejandro Balsa³ and Victoria Navarro-Compán⁴, ¹Hospital la Paz, Madrid, Spain, ²Radiology Department, Hospital La Paz, Madrid, Spain, ³Hospital Universitario La Paz, Madrid, Spain, ⁴Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain
Background/Purpose: Inflammatory back pain (IBP) is the core symptom in patients with axial spondyloarthritis (axSpA). For its assessment, experts recommend using the Assessment of SpondyloArthritis…
Abstract Number: 1041 • ACR Convergence 2023
Efficacy of Apremilast on Peripheral and Axial Inflammation in Patients with Psoriatic Arthritis Based on Whole-Body Magnetic Resonance Imaging
Mikkel Østergaard¹, Mikael Boesen², Walter P. Maksymowych³, Robert Lambert⁴, Guillermo Valenzuela⁵, Michael Bubb⁶, Olga Kubassova⁷, Jyotsna Reddy⁸, Stephen Colgan⁹, Yuri Klyachkin¹⁰, Cynthia Deignan¹¹, Zhenwei Zhou⁸ and Philip J. Mease¹², ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, ²Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Naerum, Denmark, ³Department of Medicine, University of Alberta, Edmonton, AB, Canada, ⁴Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ⁵Integral Rheumatology & Immunology Specialists, Plantation, FL, ⁶University of Florida, Gainesville, FL, ⁷Image Analysis Group, Philadelphia, PA, ⁸Amgen, Inc., Thousand Oaks, CA, ⁹Amgen, Inc., Halton Hills, ON, Canada, ¹⁰Amgen, Inc., Lexington, KY, ¹¹Amgen, Inc., Agoura Hills, CA, ¹²Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA
Background/Purpose: Apremilast is an oral phosphodiesterase 4 inhibitor with a unique immunomodulatory mechanism of action and is approved for the treatment of psoriatic arthritis (PsA).…
Abstract Number: 1868 • ACR Convergence 2023
Long-term Efficacy of a 2-year MRI Treat-to-target Strategy on Radiographic Joint Damage Progression in Rheumatoid Arthritis Patients in Clinical Remission – Five Year Follow-up of the IMAGINE-RA Randomized Clinical Trial
Signe Møller-Bisgaard¹, Kim Hørslev-Petersen², Lykke Ørnbjerg¹, Bo Ejbjerg³, Merete L Hetland¹, Jakob Moeller⁴, Robin Christensen⁵, Sabrina Mai Nielsen⁶, Daniel Glinatsi⁷, Mikael Boesen⁸, Kristian Stengaard-Pedersen⁹, Ole Rintek Madsen¹⁰, Bente Jensen¹¹, Jan Alexander Villadsen², Ellen-Margrethe Hauge⁹, Oliver Hendricks², Hanne Merete Lindegaard¹², Niels Steen Krogh¹³, Anne Grethe Jurik⁹, Henrik Thomsen⁴ and Mikkel Østergaard¹⁴, ¹Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, ²Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, ³Slagelse Hospital, Slagelse, Denmark, ⁴Herlev-Gentofte Hospital, Herlev, Denmark, ⁵Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen, Denmark, ⁶The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, ⁷Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Sweden, ⁸Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Naerum, Denmark, ⁹Aarhus University Hospital, Aarhus, Denmark, ¹⁰Herlev-Gentofte Hospital, Gentofte, Denmark, ¹¹Bispebjerg-Frederiksberg Hospital, Frederiksberg, Denmark, ¹²Odense Hospital, Odense, Denmark, ¹³ZiteLab ApS, Frederiksberg, Denmark, ¹⁴Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Radiographic joint damage progresses in 20-30% of rheumatoid arthritis (RA) patients despite fulfilling clinical remission criteria (1). Osteitis assessed on MRI is a well…
Abstract Number: 2422 • ACR Convergence 2023
Magnetic Resonance Imaging Reflects Disease Activity in the “Giant Cell Arteritis Treatment with Ultra-short Glucocorticoids and Tocilizumab” Trial (The GUSTO Trial)
Lisa Christ¹, Harald Bonel², Jennifer Cullmann³, Luca Seitz⁴, Lukas Butikofer⁵, Franca Wagner⁶ and Peter Villiger⁷, ¹Department of Rheumatology and Immunology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, ²Department of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Campusradiologie, Lindenhofspital Bern, Bern, Switzerland, ³Campusradiologie, Lindenhofspital Bern, Bern, Switzerland, ⁴Rheumatology and Immunology, Inselspital University Hospital Bern, Bern, Switzerland, ⁵CTU Bern, University of Bern, Bern, Switzerland, Bern, Switzerland, ⁶University Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland, ⁷Medical Center Monbijou, Rheumatology and Immunology, Bern, Switzerland
Background/Purpose: Magnetic resonance imaging (MRI) is well established for diagnosing giant cell arteritis (GCA). Its role in monitoring disease activity has yet to be determined.…
Abstract Number: 1162 • ACR Convergence 2023
Serial Imaging Changes in Skeletal Muscle Composition and Their Association with Clinical Outcomes in Idiopathic Inflammatory Myopathies
Mamatha Gorijavolu¹, Chengappa Kavadichanda¹, Ramesh Ananthakrishnan¹, Christina Mariaselvam¹, Molly Thabah¹ and VS Negi², ¹Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India, ²All India Institute of Medical Sciences, Bilaspur, Puducherry, India
Background/Purpose: Muscle weakness in inflammatory myopathies (IIM) is due to muscle-edema, atrophy and fatty-infiltration among which edema is the predominant cause at baseline. Some IIM…
Abstract Number: 1870 • ACR Convergence 2023
Assessing the Appropriateness of Imaging Modalities in Primary Care for Low Back Pain and Their Impact on Outcomes: A Retrospective Observational Study in a Single Center in Trenton
Damira Sereda¹, Cristine Arcilla², Kudret Arslan³ and Daniel Goldsmith⁴, ¹Capital Health Medical Canter, Trenton, NJ, ²Capital Health Regional Medical Center, Ewing Township, NJ, ³Capital Health Medical Center, Trenton, NJ, ⁴Capital Health Regional Medical Center, Trenton, NJ
Background/Purpose: Low back pain (LBP) is a leading cause of doctor visits and disability. The annual direct expenditures for LBP management exceed $80 billion, not…
Abstract Number: 2549 • ACR Convergence 2023
Effect of Ixekizumab Treatment on MRI Structural Lesions in the Sacroiliac Joints of Patients with Radiographic Axial Spondyloarthritis; A Post-hoc Analysis of a Placebo and Active Controlled RCT
Walter P. Maksymowych¹, Robert Lambert², Eswar Krishnan³, Baojin Zhu³, Rebecca Bolce³ and Mikkel Østergaard⁴, ¹University of Alberta, Edmonton, AB, Canada, ²Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ³Eli Lilly and Company, Indianapolis, IN, ⁴Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark
Background/Purpose: The effect of Ixekizumab (IXE) on structural lesions in the sacroiliac joints (SIJ) of patients (pts) with radiographic Axial Spondylarthritis (r-axSpA) assessed by magnetic…
Abstract Number: 1194 • ACR Convergence 2023
Extent of Subregional Involvement of Subchondral Bone Marrow Lesions in Incident Knee OA Is Associated with Weight-Bearing Knee Pain
Kent Kwoh¹, Frank Roemer², Erin Ashbeck³ and Ali Guermazi⁴, ¹University of Arizona, Tucson, AZ, ²Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany, ³University of Arizona Arthritis Center, Tucson, AZ, ⁴Boston University, Boston, MA
Background/Purpose: Subchondral bone marrow lesions (BMLs) have been associated with incident and progressive pain and reported to fluctuate along with concurrent fluctuations in symptoms. While…
Abstract Number: 1872 • ACR Convergence 2023
Performance Analysis of a Deep Learning Algorithm to Detect Positive SIJ MRI According to the ASAS Definition in axSpA Patients
Joeri Nicolaes¹, Evi Tselenti², Theodore Aouad³, Clementina López Medina⁴, Antoine Feydy⁵, Hugues Talbot³, Bengt Hoepken⁶, Natasha De Peyrecave⁷ and Maxime Dougados⁸, ¹KU Leuven, Department of Electrical Engineering (ESAT), Center for Processing Speech and Images; UCB Pharma, Anderlecht, Belgium, ²Veramed, London, United Kingdom, ³CentraleSupélec, Universite Paris-Saclay, Inria, Gif-sur-Yvette, France, ⁴Rheumatology Department, Cochin Hospital; INSERM (U1153): Clinical Epidemiology and Biostatistics, University of Paris; Rheumatology Department, Reina Sofia Hospital, Cordoba / IMIBIC / University of Cordoba, Cordoba, Spain, ⁵INSERM (U1153): Clinical Epidemiology and Biostatistics, University of Paris; Radiology Department, Cochin Hospital, Paris, France, ⁶UCB Pharma, Monheim, Germany, ⁷UCB Pharma, Brussels, Belgium, ⁸Rheumatology Department, Cochin Hospital; INSERM (U1153): Clinical Epidemiology and Biostatistics, University of Paris, Paris, France
Background/Purpose: Magnetic resonance imaging (MRI) of the sacroiliac joints (SIJ) is an essential tool in the evaluation of patients with axial spondyloarthritis (axSpA). In-depth knowledge…
Abstract Number: 1235 • ACR Convergence 2023
Apparent Diffusion Coefficient (ADC) from Diffusion Weighted Imaging (DWI) as an Objective Tool to Differentiate Normal Maturational Subchondral Signal from Inflammation at the Sacroiliac Joint in Youth
Michael L. Francavilla¹, Dmitry Khrichenko², Timothy G. Brandon², Nancy A. Chauvin³, Rui Xiao⁴ and Pamela F. Weiss⁵, ¹University of South Alabama College of Medicine, Mobile, AL, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³The Cleveland Clinic, Hummelstown, PA, ⁴University of Pennsylvania, Philadelphia, PA, ⁵Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: There is a critical need for tools to distinguish between maturational changes mimicking subchondral edema from pathologic inflammation within the SI joints on MRI.…
Abstract Number: 1874 • ACR Convergence 2023
Cartilage Thickness Measures Are More Responsive Than Cartilage Area Loss Measures: A Comparison of Quantitative and Semi-quantitative Cartilage Assessments from the Osteoarthritis Initiative
Aaron Ray¹, Alan Brett², Bright Dube³, Michael Bowes⁴ and Philip Conaghan³, ¹York and Scarborough Teaching Hospitals: NHS Foundation Trust, York, United Kingdom, ²Stryker, Austin, TX, ³University of Leeds, Leeds, United Kingdom, ⁴Imorphics Ltd, Manchester, United Kingdom
Background/Purpose: Cartilage loss in 1-2 year osteoarthritis clinical trials is often small, but a critical outcome measure. The aim of this study was to compare…
Abstract Number: 1300 • ACR Convergence 2023
Bone Marrow Edema in MRI Is More Associated with Rapid Radiographic Progression Than Clinically Relevant Radiographic Progression
Kou Katayama¹, Takanobu Okubo², Toshikazu Sato¹, Kitaru Tanaka³, Tomoki Kawahata³, Yuichi Makino⁴ and Hiroshi Ito⁵, ¹Department of Orthopedic Surgery, Katayama Orthopedic Rheumatology Clinic, Asahikawa, Japan, ²Department of Radiology, Katayama Orthopedic Rheumatology Clinic, Asahikawa, Japan, ³Division of Metabolism and Biosystemic Science, Gastroenterology, and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan, ⁴Department of Medicine, Division of Rheumatology, Asahikawa Medical University Hospital, Asahikawa, Japan, ⁵Department of orthpedic surgery, Asahikawa Medical University, Asahikawa, Japan
Background/Purpose: Rapid radiographic progression (RRP) is selected as one of the risk factors for difficult- to- treat RA, which needs to be resolved as soon…
Abstract Number: 1878 • ACR Convergence 2023
MRI-determined Intramuscular Fat Changes During Oral Glucocorticoid Treatment: Findings from a Feasibility Study
Thurkka Rajeswaran¹, Emma Harris², hannah Mathieson¹, John Biglands³, Paul Stewart¹, Ai Lyn Tan¹ and Sarah Mackie⁴, ¹University of Leeds, Leeds, United Kingdom, ²The Open University, Milton Keynes, United Kingdom, ³NIHR Leeds Biomedical Research Centre and Medical Physics and Engineering , Leeds Teaching Hospitals NHS Trust Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: Oral glucocorticoid therapy has many adverse effects including insulin resistance and myopathy. Long-term glucocorticoid therapy causes a "sarcopenic obesity" phenotype of adiposity with muscle…

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