ACR Meeting Abstracts

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Abstracts tagged "Magnetic resonance imaging (MRI)"

  • Abstract Number: 1621 • ACR Convergence 2023

    Maxillofacial MRI Augments Detection of Non-CNS Abnormalities in Pediatric Craniofacial Scleroderma

    Daniel Glaser1, Amy Metry2, Elena DeRosas2, Subramanian Subramanian2 and Kathryn Torok3, 1Yale University School of Medicine, New Haven, CT, 2University of Pittsburgh, Pittsburgh, PA, 3University of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA

    Background/Purpose: Craniofacial scleroderma is a rare subtype of linear scleroderma affecting the head and neck. Up to 40% of patients experience extracutaneous manifestations (ECMs), but…
  • Abstract Number: 1989 • ACR Convergence 2023

    Shared Variation Among Cartilage Thickness Change Maps and Baseline Clinical Features at the Initiation of Structural Knee Osteoarthritis

    Thomas Keefe1, Marc Niethammer1, Boqi Chen1, Zhengyang Shen1, Daniel Nissman1, Mary Catherine Minnig2, Yvonne Golightly3, J.S. Marron1 and Amanda Nelson1, 1University of North Carolina at Chapel Hill, Chapel Hill, NC, 2University of North Carolina at Chapel Hill, Durham, NC, 3University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: To identify features of cartilage thickness change and baseline clinical indicators associated with the transition from normal to mildly reduced joint space as an…
  • Abstract Number: 0843 • ACR Convergence 2023

    Predictive Validity of Data-driven Definitions for Active and Structural Lesions in the SI Joints Typical for Axial SpA: A 2-year Follow-up in the SPondyloArthritis Caught Early Cohort

    Liese de Bruin1, Mary Lucy marques2, Miranda Van Lunteren3, Manouk de Hooge4, Sofia Exarchou5, Floris Van Gaalen3, Désirée van der Heijde6 and Sofia Ramiro6, 1Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Center; Centro Hospitalar e Universitário de Coimbra (Department of Rheumatology), Coimbra, Portugal, 3Leiden University Medical Center, Department of Rheumatology, Leiden, Netherlands, 4Ghent University Hospital, Hesperange, Luxembourg, 5Lund University, Åkarp, Sweden, 6Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The Assessment of Spondyloarthritis international Society MRI (ASAS MRI) group has proposed definitions for active and structural lesions typical for axial SpA (axSpA) on…
  • Abstract Number: 1648 • ACR Convergence 2023

    EULAR Recommendations for the Use of Imaging in Large Vessel Vasculitis in Clinical Practice: 2023 Update

    Christian Dejaco1, Sofia Ramiro2, Milena Bond3, Philipp Bosch4, Cristina Ponte5, Sarah Mackie6, Thorsten Bley7, Daniel Blockmans8, Sara Brolin9, Ertugrul Cagri Bolek10, Rebecca Cassie11, Maria C Cid12, Juan Molina-Collada13, Bhaskar Dasgupta14, Berit Dalsgaard Nielsen15, Eugenio De Miguel16, Haner Direskeneli17, Christina Duftner18, Alojzija Hocevar19, Anna Molto20, Valentin Sebastian Schäfer21, Luca Seitz22, Riemer H.J.A. Slart23 and Wolfgang Schmidt24, 1Azienda Sanitaria Alto Adige, Brunico, Italy, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Azienda sanitaria dell'Alto Adige, Merano, Italy, 4Medical University of Graz, Graz, Austria, 5Department of Rheumatology, Centro Hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Lisbon, Portugal; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Portugal, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 7Institute of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany, 8Department of General Internal Medicine, University Hospitals Leuven, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium, 9Karolinska University Hospital, and Karolinska Institutet, Stockholm, Sweden, 101-Hacettepe University Vasculitis Research Centre, Ankara, Turkey/ 2-Vasculitis Translational Research Program, NIAMS, NIH, US, Ankara, Turkey, 11n/a, Leicester, United Kingdom, 12Hospital Clinic Barcelona, Barcelona, Spain, 13Hospital General Universitario Gregorio Marañón, Madrid, Spain, 14Mid & South Essex University Hospitals NHS Foundation Trust; Southend University Hospital, Westcliff-on-sea, United Kingdom, 15Department of Internal Medicine, Horsens, Denmark, 16Hospital Universitario La Paz, Madrid, Spain, 17Division of Rheumatology, Medical School, Marmara University, Istanbul, Turkey, 18Medical University Innsbruck, Innsbruck, Austria, 19Department of Rheumatology, Universitiy Medical Centre Ljubljana, Ljubljana, Slovenia, 20HOPITAL COCHIN AP-HP, Service de Rhumatologie, Paris, France, 21Clinic of Internal Medicine III, Department of Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital of Bonn, Bonn, Germany, 22Rheumatology and Immunology, Inselspital University Hospital Bern, Bern, Switzerland, 23University of Twente, Enschede, Netherlands, 24Rheumatology, Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany

    Background/Purpose: Imaging recommendations for primary large vessel vasculitis (LVV) were developed in 2018. Several new studies have emerged since then, and an update of the…
  • Abstract Number: 1991 • ACR Convergence 2023

    Therapeutic Efficacy of Intra Articular Injection of Human Bone Marrow Derived Mesenchymal Stem Cells in Knee Osteoarthritis; Randomized, Double-blind, Placebo-controlled Clinical Trial

    Ji Won Yang, Bong-Woo Lee, Jennifer Lee and Ji Hyeon Ju, Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Background/Purpose: Osteoarthritis (OA) is severe and intractable musculoskeletal disease that eventually leads to joint failure and pain due to inflammation and joint injury. Mesenchymal stem…
  • Abstract Number: 0844 • ACR Convergence 2023

    Facet Joint Inflammation Is Rare, but When Present It Is Associated with Facet Joint Ankylosis in Radiographic Axial Spondyloarthritis Patients from the SIAS Cohort

    Manouk de Hooge1, Rosalinde Stal2, Alexandre Sepriano3, Xenofon Baraliakos4, Monique Reijnierse5, Juergen Braun6, Désirée van der Heijde7, Floris Van Gaalen2 and Sofia Ramiro7, 1Ghent University Hospital, Hesperange, Luxembourg, 2Leiden University Medical Center, Department of Rheumatology, Leiden, Netherlands, 3Leiden University Medical Centre, Portela Loures, Portugal, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 5Leiden University Medical Center, Leiden, Netherlands, 6Ruhr-Universität Bochum and Rheumazentrum Ruhrgebiet, Herne, Germany, 7Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: To assess whether posterior element (PE) inflammation, in particular in the facet joints (FJ), is associated with new facet joint ankylosis on MRI one…
  • Abstract Number: 1865 • ACR Convergence 2023

    Is Flexion Contracture in Knee Osteoarthritis Associated with MRI Pathologies over Time? Data from the Osteoarthritis Initiative

    Daniel Chan Chun Kong1, Philip Conaghan2 and Mark Campbell3, 1University of Ottawa, Ottawa, ON, Canada, 2University of Leeds, Leeds, United Kingdom, 3Elisabeth Bruyere Hospital, Ottawa, ON, Canada

    Background/Purpose: Knee flexion contracture (FC) is associated with worse clinical outcomes in those with knee OA. Cross sectional data demonstrated that knee FC was associated…
  • Abstract Number: 2048 • ACR Convergence 2023

    Development and Usability Testing of Web-based Standardized Scoring Tool for Magnetic Resonance Images from Children with Chronic Nonbacterial Osteomyelitis (CNO)

    Farzana Nuruzzaman1, T. Shawn Sato2, Andrew Carbert3, Joel Paschke3, Lauren Potts4, Meinrad Beer5, Mingqian Huang6, Ramesh Iyer7, Johanna Monsalve8, Anh-Vo Ngo7, Jennifer Stimec9, Mahesh Thapa7, Xiaoyue Zhang10, Walter P. Maksymowych11, Polly Ferguson12 and Yongdong (Dan) Zhao13, 1Stony Brook Children's Hospital, Stony Brook, NY, 2University of Iowa, Iowa City, IA, 3CARE Arthritis, Edmonton, AB, Canada, 4Illustrator/Patient Research Partner, Long Beach, CA, 5University Hospital, Ulm Germany, Ulm, Germany, 6Mount Sinai Hospital, New York, NY, 7University of Washington, Seattle, WA, 8SUNY-Stony Brook Hospital, Stonybrook, NY, 9The Hospital for Sick Children, Toronto, ON, Canada, 10Biostatistical Consulting Core - Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, 11University of Alberta, Edmonton, AB, Canada, 12University of Iowa Carver College of Medicine, Iowa City, IA, 13University of Washington, Redmond, WA

    Background/Purpose: The ChRonic nonbacterial Osteomyelitis Magnetic Resonance Imaging Scoring (CROMRIS) tool was developed but it was not digitized yet. Our objectives are: 1) to adapt…
  • Abstract Number: 1038 • ACR Convergence 2023

    Improved Assessment of Structural Damage in the Spine in Patients with Axial Spondyloarthritis by MRI-based Synthetic CT: A Comparison with Low-dose CT and X-ray

    Simone Tromborg Willesen1, Nora Vladimirova1, Jakob Moeller2, Anna Enevold Fløistrup Hadsbjerg1, Bimal Mayur Kumar Vora3, Sengul Seven1, Susanne Juhl Pedersen1 and Mikkel Østergaard1, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, 2Herlev-Gentofte Hospital, Herlev, Denmark, 3Singapore General Hospital, Singapore, Singapore

    Background/Purpose: Whether a therapy has bone structure-modifying effects in the spine is crucial to determine since this is a prerequisite for a therapy to reduce…
  • Abstract Number: 1866 • ACR Convergence 2023

    MRI Confirms MRE Evidence of Sacroiliitis in Many with Crohn’s Disease: A Prospective Study for the Screening of axSpA in High-risk Populations

    Fardina Malik1, Soterios Gyftopoulos1, Jordan Axelrad1, Shannon Chang1, Simon Hong1, Maia McAllister2, Morayo Kendra Olateru Olagbegi3, Erin Alaia1, William Walter1, Accelerating Medicines Partnership Program RA SLE Network4, David Hudesman1 and Jose Scher5, 1NYU Grossman School of Medicine, New York, NY, 2NYU, New York, NY, 3New York University, New York, NY, 4Cedars-Sinai Medical Center, Los Angeles, CA, 5New York University School of Medicine, New York, NY

    Background/Purpose: Sacroiliitis can be detected incidentally on magnetic resonance enterography (MRE) scans in Crohn's disease (CD) patients, obtained for CD assessment during clinical practice. However,…
  • Abstract Number: 2203 • ACR Convergence 2023

    Self-Reported and Physician´s Assessment of Inflammatory Back Pain According to ASAS Criteria: Is It the Same?

    Diego Benavent1, Mar Tapia2, Daniel Bernabeu2, Victor muley2, Chamaida Plasencia-Rodríguez3, Alejandro Balsa3 and Victoria Navarro-Compán4, 1Hospital la Paz, Madrid, Spain, 2Radiology Department, Hospital La Paz, Madrid, Spain, 3Hospital Universitario La Paz, Madrid, Spain, 4Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain

    Background/Purpose: Inflammatory back pain (IBP) is the core symptom in patients with axial spondyloarthritis (axSpA). For its assessment, experts recommend using the Assessment of SpondyloArthritis…
  • Abstract Number: 1041 • ACR Convergence 2023

    Efficacy of Apremilast on Peripheral and Axial Inflammation in Patients with Psoriatic Arthritis Based on Whole-Body Magnetic Resonance Imaging

    Mikkel Østergaard1, Mikael Boesen2, Walter P. Maksymowych3, Robert Lambert4, Guillermo Valenzuela5, Michael Bubb6, Olga Kubassova7, Jyotsna Reddy8, Stephen Colgan9, Yuri Klyachkin10, Cynthia Deignan11, Zhenwei Zhou8 and Philip J. Mease12, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, 2Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Naerum, Denmark, 3Department of Medicine, University of Alberta, Edmonton, AB, Canada, 4Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, 5Integral Rheumatology & Immunology Specialists, Plantation, FL, 6University of Florida, Gainesville, FL, 7Image Analysis Group, Philadelphia, PA, 8Amgen, Inc., Thousand Oaks, CA, 9Amgen, Inc., Halton Hills, ON, Canada, 10Amgen, Inc., Lexington, KY, 11Amgen, Inc., Agoura Hills, CA, 12Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA

    Background/Purpose: Apremilast is an oral phosphodiesterase 4 inhibitor with a unique immunomodulatory mechanism of action and is approved for the treatment of psoriatic arthritis (PsA).…
  • Abstract Number: 1868 • ACR Convergence 2023

    Long-term Efficacy of a 2-year MRI Treat-to-target Strategy on Radiographic Joint Damage Progression in Rheumatoid Arthritis Patients in Clinical Remission – Five Year Follow-up of the IMAGINE-RA Randomized Clinical Trial

    Signe Møller-Bisgaard1, Kim Hørslev-Petersen2, Lykke Ørnbjerg1, Bo Ejbjerg3, Merete L Hetland1, Jakob Moeller4, Robin Christensen5, Sabrina Mai Nielsen6, Daniel Glinatsi7, Mikael Boesen8, Kristian Stengaard-Pedersen9, Ole Rintek Madsen10, Bente Jensen11, Jan Alexander Villadsen2, Ellen-Margrethe Hauge9, Oliver Hendricks2, Hanne Merete Lindegaard12, Niels Steen Krogh13, Anne Grethe Jurik9, Henrik Thomsen4 and Mikkel Østergaard14, 1Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, 2Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, 3Slagelse Hospital, Slagelse, Denmark, 4Herlev-Gentofte Hospital, Herlev, Denmark, 5Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen, Denmark, 6The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, 7Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Sweden, 8Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Naerum, Denmark, 9Aarhus University Hospital, Aarhus, Denmark, 10Herlev-Gentofte Hospital, Gentofte, Denmark, 11Bispebjerg-Frederiksberg Hospital, Frederiksberg, Denmark, 12Odense Hospital, Odense, Denmark, 13ZiteLab ApS, Frederiksberg, Denmark, 14Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark

    Background/Purpose: Radiographic joint damage progresses in 20-30% of rheumatoid arthritis (RA) patients despite fulfilling clinical remission criteria (1). Osteitis assessed on MRI is a well…
  • Abstract Number: 2422 • ACR Convergence 2023

    Magnetic Resonance Imaging Reflects Disease Activity in the “Giant Cell Arteritis Treatment with Ultra-short Glucocorticoids and Tocilizumab” Trial (The GUSTO Trial)

    Lisa Christ1, Harald Bonel2, Jennifer Cullmann3, Luca Seitz4, Lukas Butikofer5, Franca Wagner6 and Peter Villiger7, 1Department of Rheumatology and Immunology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, 2Department of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Campusradiologie, Lindenhofspital Bern, Bern, Switzerland, 3Campusradiologie, Lindenhofspital Bern, Bern, Switzerland, 4Rheumatology and Immunology, Inselspital University Hospital Bern, Bern, Switzerland, 5CTU Bern, University of Bern, Bern, Switzerland, Bern, Switzerland, 6University Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland, 7Medical Center Monbijou, Rheumatology and Immunology, Bern, Switzerland

    Background/Purpose: Magnetic resonance imaging (MRI) is well established for diagnosing giant cell arteritis (GCA). Its role in monitoring disease activity has yet to be determined.…
  • Abstract Number: 1162 • ACR Convergence 2023

    Serial Imaging Changes in Skeletal Muscle Composition and Their Association with Clinical Outcomes in Idiopathic Inflammatory Myopathies

    Mamatha Gorijavolu1, Chengappa Kavadichanda1, Ramesh Ananthakrishnan1, Christina Mariaselvam1, Molly Thabah1 and VS Negi2, 1Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India, 2All India Institute of Medical Sciences, Bilaspur, Puducherry, India

    Background/Purpose: Muscle weakness in inflammatory myopathies (IIM) is due to muscle-edema, atrophy and fatty-infiltration among which edema is the predominant cause at baseline. Some IIM…
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