Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1854 • ACR Convergence 2025
Resting-State Functional Magnetic Resonance Imaging Analysis Revealed Altered Functional Connectivity Associated with Fatigue in Systemic Lupus Erythematosus
Yujie Song¹, Nobuya Abe¹, Yuichiro Fujieda², Kodai Sakiyama¹, Yuta Inoue¹, Kenichi Miyamoto¹, Kazuro Kamada¹, Yotaro Oki¹, Maria Tada¹, Shuhei Takeyama¹, Ryo Hisada², Michihito Kono² and Tatsuya Atsumi², ¹Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ²Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan
Background/Purpose: Fatigue is one of the most frequent constitutional symptoms in systemic lupus erythematosus (SLE), usually accompanied with impaired quality of life. Resting-state functional magnetic…
Abstract Number: 2625 • ACR Convergence 2025
Early Detection of Knee Osteoarthritis – The Role of a Composite Disease Activity Metric: Data from the Osteoarthritis Initiative
Julieann Patarini¹, Timothy McAlindon², Jonggyu Baek¹, Emily Kirillov³, Nhung Vo³, Michael Richard³, Ming Zhang⁴, Matthew Harkey⁵, Grace Lo⁶, Shao-Hsien Liu¹, Kate Lapane¹, Charles Eaton⁷, James Mackay⁸ and Jeffrey Driban⁹, ¹UMass Chan Medical School, Worcester, MA, ²UMass Chan School of Medicine, Arlington, MA, ³Tufts Medical Center, Boston, MA, ⁴Boston University, Westford, MA, ⁵Michigan State University, East Lansing, MI, ⁶Baylor College of Medicine / MEDVAMC, Houston, TX, ⁷Brown University, Pawtucket, RI, ⁸University of Cambridge; Norwich Medical School, San Diego, CA, ⁹University of Massachusetts Chan Medical School, Marlborough, NH

Background/Purpose: Bone marrow lesions (BMLs) and effusion-synovitis are frequent and dynamic disease processes detected from early- to late-stage knee OA. These processes are associated with…
Abstract Number: 0323 • ACR Convergence 2025
Automated Effusion-Synovitis Volume is Prognostic and Responsive to Knee Osteoarthritis Progression: Data from the Osteoarthritis Initiative
Jeffrey Driban¹, Kate Lapane², Shao-Hsien Liu², Jonggyu Baek², Grace Lo³, Matthew Harkey⁴, Charles Eaton⁵, James Mackay⁶, Timothy McAlindon⁷, Mohammad Chowdhury⁸, Zhen Cao⁹, Juan Shan¹⁰ and Ming Zhang¹¹, ¹University of Massachusetts Chan Medical School, Marlborough, NH, ²UMass Chan Medical School, Worcester, MA, ³Baylor College of Medicine / MEDVAMC, Houston, TX, ⁴Michigan State University, East Lansing, MI, ⁵Brown University, Pawtucket, RI, ⁶University of Cambridge; Norwich Medical School, San Diego, CA, ⁷UMass Chan School of Medicine, Arlington, MA, ⁸Pace University, New York City, NY, ⁹Boston University, Boston, MA, ¹⁰Pace University, New York, NY, ¹¹Boston University, Westford, MA

Background/Purpose: Semi-quantitative and semi-automated quantitative measurements of effusion-synovitis (ES) are prognostic for knee OA progression. Changes in these metrics relate to changes in knee pain.…
Abstract Number: 1937 • ACR Convergence 2025
Does Combining Standard MRI-Based Scores with Radiographic Trabecular Bone Texture Biomarkers Improve Predictive Performance for Radiographic Knee Osteoarthritis Progression?
Ahmad Almhdie-Imjabbar¹, Saida Daroussi², Daniela Herrera³, Hechmi Toumi² and Eric Lespessailles⁴, ¹University Hospital Center of Orleans, Orleans, France, ²PRIMMO- University Hospital Center of Orleans, Orleans, France, ³PRIMMO- University Hospital Center of Orleans, Olreans, France, ⁴CHU Orléans, Orléans, France
Background/Purpose: Knee osteoarthritis (KOA) is a major cause of disability worldwide, particularly impacting the elderly and obese population. Radiographic trabecular bone texture (TBT) is demonstrated…
Abstract Number: 2635 • ACR Convergence 2025
Differences in structural lesions of the spine between patients with early axSpA and non-axSpA chronic back pain: 2-year results of the SPACE Cohort
Gizem Ayan¹, Liese de Bruin², Miranda van Lunteren², Manouk de Hooge³, Ana Bento da Silva², Mary Lucy Marques⁴, Monique Reijnierse⁵, Victoria Navarro-Compan⁶, Marleen van de sande⁷, Inger Jorid Berg⁸, Roberta Ramonda⁹, Sofia Exarchou¹⁰, Désirée Van Der Heijde², Floris A. van Gaalen² and Sofia Ramiro¹¹, ¹Ankara Research and Training Hospital, Ankara, Turkey, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; and Coimbra Local Health Unit, Coimbra, Portugal, ⁵Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁶Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, ⁷The Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Amsterdam, Netherlands, ⁸Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, ⁹Rheumatology Unit-DIMED-University of Padova ITALY, Padova, Padua, Italy, ¹⁰Lund University, Åkarp, Skane Lan, Sweden, ¹¹Leiden University Medical Center, Bunde, Netherlands
Background/Purpose: The difference in spinal structural lesions and their progression over time between chronic back pain (CBP) patients with and without early axSpA is unknown.…
Abstract Number: 0390 • ACR Convergence 2025
Radiographic Assessment in Juvenile Spondyloarthritis: Evaluating the axJSpA Criteria Using Radiographs Alone Versus MRI
David M. Biko¹, Nancy A. Chauvin², Michael Francavilla³, Nele Herregods⁴, Walter P. Maksymowych⁵, Robert G. W. Lambert⁶, Timothy Brandon¹, Ozgur Kasapcopur⁷, Mehmet YILDIZ⁸, Hemalatha Srinivasalu⁹ and Pamela Weiss¹⁰, ¹Children's Hospital of Philadelphia, Philadelphia, PA, ²The Cleveland Clinic, Hummelstown, PA, ³Department of Pediatric Radiology, Children’s Hospital Philadelphia, Philadelphia, PA, ⁴Ghent University Hospital, Ghent, Belgium, ⁵Department of Medicine, University of Alberta, ⁵⁶⁸ Heritage Building, Edmonton, AB, Canada, ⁶University of Alberta, Department of Radiology & Diagnostic Imaging, Edmonton, AB, Canada, ⁷Istanbul University-Cerrahpasa, Cerrahpasa Medical School, istanbul, Turkey, ⁸Istanbul University-Cerrahpasa Department of Pediatric Rheumatology, Istanbul, Turkey, ⁹Children's National Hospital, Washington, DC, ¹⁰Childrens Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Radiographs are neither sensitive nor reliable for assessing axial disease in juvenile spondyloarthritis (JSpA), though they are still used in some settings due to…
Abstract Number: 1945 • ACR Convergence 2025
Significance of Finger Joint Tenderness With or Without Swelling in Relation to MRI, Ultrasound, and X-Ray Findings in Psoriatic Arthritis_Final results
Victoria Furer¹, iris Eshed², Moshe Iluz¹, Ori Elkayam³ and Ari Polachek⁴, ¹Tel-Aviv Medical Center, Tel-Aviv, Israel, ²Department of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer affiliated with School of Medicine, Tel Aviv University, Tel Aviv, Israel, ³Tel Aviv medical center, Tel Aviv, Israel, ⁴Rheumatology Institute of Beilinson Hospital, Petah Tikva, Israel
Background/Purpose: Musculoskeletal involvement in psoriatic arthritis (PsA) affects both articular and extra-articular structures, presenting as inflammatory and structural lesions. The relationship between tender and/or swollen…
Abstract Number: 2677 • ACR Convergence 2025
Quantified Imaging Response at the Sacroiliac Joints to TNF-Inhibitor Therapy in Youth with Axial Disease
Timothy Brandon¹, Rui Xiao², Daniel Lovell³, Edward Oberle⁴, Matthew Stoll⁵, Nancy A. Chauvin⁶, Michael Francavilla⁷, Walter P. Maksymowych⁸ and Pamela Weiss⁹, ¹Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Nationwide Children's Hospital, Columbus, OH, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶The Cleveland Clinic, Hummelstown, PA, ⁷Department of Pediatric Radiology, Children’s Hospital Philadelphia, Philadelphia, PA, ⁸Department of Medicine, University of Alberta, ⁵⁶⁸ Heritage Building, Edmonton, AB, Canada, ⁹Childrens Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: This study assessed the timeline for the resolution of inflammation, changes in structural lesions at the sacroiliac joints (SIJ), and their correlation with patient-reported…
Abstract Number: 0656 • ACR Convergence 2024
Lupus Myocarditis: Clinical Characteristics, Cardiac Magnetic Resonance Imaging Findings and Outcomes
María del Carmen Zamora-Medina¹, Erik Cimé-Aké², Emilio G. Lazarini², Wallace Rafael A. Muñoz-Castañeda³ and Hilda Fragoso-Loyo², ¹Instituto Nacional de Perinatología "Isidro Espinoza de los Reyes". Rheumatology Department, Mexico City, Distrito Federal, Mexico, ²Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Immunology and Rheumatology Department, Mexico City, Mexico, ³Hospital Medica Sur. Rheumatology Department, Mexico City, Distrito Federal, Mexico
Background/Purpose: Limited information about lupus myocarditis (LM) comes from small case series. The aim of our study is to describe and compare clinical characteristics, cardiac…
Abstract Number: 1478 • ACR Convergence 2024
Associations Between Clinical Characteristics and Screening MRI Findings: Exploratory Analysis of the Ongoing Phase 4, Multicenter, Randomized, Controlled STAR Study of Biologic-Naïve Patients with PsA with MRI-Confirmed Axial Involvement
Xenofon Baraliakos¹, Paul Bird², Atul Deodhar³, Dafna Gladman⁴, Philip S. Helliwell⁵, Denis Poddubnyy⁶, Arthur Kavanaugh⁷, Mikkel Ostergaard⁸, Enrique R. Soriano⁹, Lai-shan Tam¹⁰, Soumya Chakravarty¹¹, Evan Leibowitz¹², Cinty Gong¹³, Stephen Xu¹⁴, Thomas Fuerst¹⁵, Nadeem Saeed¹⁶, Robert Landewé¹⁷ and Philip Mease¹⁸, ¹Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ²University of New South Wales, Randwick, NSW, Sydney, New South Wales, Australia, ³Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, ⁴University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK, Leeds, United Kingdom, ⁶Charite-Universitatsmedizin Berlin, Berlin, Germany, ⁷University of California San Diego, La Jolla, CA, ⁸Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, ⁹Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ¹⁰The Chinese University of Hong Kong, New Territories, Hong Kong, ¹¹Janssen Scientific Affairs, LLC, Horsham/ Drexel University College of Medicine, Philadelphia, Horsham, PA, ¹²Janssen Scientific Affairs, LLC, Fair Lawn, NJ, ¹³Janssen Scientific Affairs, Horsham, PA, ¹⁴Janssen Research & Development, LLC, Spring House, PA, USA, Spring House, PA, ¹⁵Clario, San Mateo, CA, ¹⁶Clario, San Mateo, ¹⁷Amsterdam University Medical Center, Meerssen, Netherlands, ¹⁸Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA
Background/Purpose: Patients (pts) with PsA can develop axial inflammation in the SI joints (SIJs) and/or spine. Although validated classification criteria for axial spondyloarthritis exist, established…
Abstract Number: 0683 • ACR Convergence 2024
Prognostic Value of Systemic Sclerosis-associated Primary Heart Involvement
Caya Gharibian¹, Vanessa Lupi¹, Alexander Gotschy¹, Mike Becker², Rucsandra Dobrota¹, Muriel Elhai³, Sinziana Muraru¹, Suzana Jordan¹, Anna-Maria Hoffmann-Vold⁴, Oliver Distler⁵, Robert Manka¹, Cosimo Bruni¹ and Carina Mihai¹, ¹University Hospital Zurich, University of Zurich, Zurich, Switzerland, ²Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, ³University Hospital zurich, Zürich, Switzerland, ⁴Oslo University Hospital, Oslo, Norway, ⁵Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Zurich, Switzerland
Background/Purpose: A definition of primary heart involvement (pHI) in systemic sclerosis (SSc) was recently developed (Bruni C et al. J Scleroderma Relat Disord. 2022;7:24-32). Cardiac…
Abstract Number: 1635 • ACR Convergence 2024
Magnetic Resonance Imaging for Therapy Monitoring in Giant Cell Arteritis – Impact on Disease Management
Matthias Froehlich¹, Michael Gernert², Marc Schmalzing³, Patrick-Pascal Strunz⁴, Hanna Labinsky⁵, Thorsten A. Bley⁶ and Konstanze V. Guggenberger⁶, ¹Uniklinikum Wuerzburg, Medizinische Klinik II, Wuerzburg, Germany, ²Medicine II, Division Rheumatology/Clinical Immunology, University Hospital of Wuerzburg, Wuerzburg, ³University Hospital Wuerzburg, Würzburg, Germany, ⁴University hospital of Wuerzburg, Wuerzburg, Germany, ⁵University Hospital Würzburg, Wuerzburg, Germany, ⁶University Hospital Würzburg, Würzburg, Germany
Background/Purpose: Imaging techniques such as magnetic resonance imaging (MRI) are a cornerstone for the diagnosis of giant cell arteritis (GCA). In the further course of…
Abstract Number: 0689 • ACR Convergence 2024
Arrhythmic Burden, Myocardial Markers, and Long-term Survival in Distinct Cardiac Magnetic Resonance Subsets of Systemic Sclerosis
Silvia Laura Bosello¹, Enrico De Lorenzis², Giacomo De Luca³, Antonio Tonutti⁴, veronica Batani⁵, Pier Giacomo Cerasuolo⁶, Gerlando Natalello⁷, Lucia Lanzo⁶, Gabriella Alonzi⁶, Silvia Fiore⁶, Stefano Di Murro⁶, Andrea Zoli⁶, Valentina Boni⁶, Riccardo Marano⁸, Francesca Augusta Gabrielli⁹, Francesco Del Galdo¹⁰, Dan Knight¹¹, Vivek Muthurangu¹¹, Christopher Denton¹², Maria De Santis⁴, Marco Matucci Cerinic⁵ and Maria Antonietta D'Agostino¹³, ¹Unit of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²Catholic University of the Sacred Heart, Roma, Rome, Italy, ³Vita-Salute San Raffaele University & IRCCS San Raffaele Hospital, Milan, Milan, Italy, ⁴Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy, ⁵Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy, ⁶Division of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ⁷Division of Rheumatology - Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, ⁸Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy, ⁹Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ¹⁰University of Leeds, Leeds, United Kingdom, ¹¹UCL Department of Cardiac MRI, University College London (Royal Free Campus), London, United Kingdom, ¹²University College London, Northwood, United Kingdom, ¹³Division of Rheumatology, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy
Background/Purpose: Cardiac involvement in Systemic Sclerosis (SSc) is widely recognized as heterogeneous and, when clinically evident, it is associated with a poor prognosis. Recently, five…
Abstract Number: 1757 • ACR Convergence 2024
Bimekizumab Treatment Resulted in Improvements in MRI Inflammatory and Structural Lesions in the Sacroiliac Joints of Patients with Axial Spondyloarthritis: 52-Week Results and Post Hoc Analyses from Two Phase 3 Studies
Walter Maksymowych¹, Sofia Ramiro², Denis Poddubnyy³, Xenofon Baraliakos⁴, Robert Lambert¹, Ute Massow⁵, Thomas Vaux⁶, Chetan Prajapati⁶, Alexander Marten⁵, Natasha de Peyrecave⁷ and Mikkel Ostergaard⁸, ¹University of Alberta, Edmonton, AB, Canada, ²Leiden University Medical Center, Bunde, Netherlands, ³Charite-Universitatsmedizin Berlin, Berlin, Germany, ⁴Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁵UCB Pharma, Monheim am Rhein, Germany, ⁶UCB Pharma, Slough, United Kingdom, ⁷UCB Pharma, Brussels, Belgium, ⁸Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark
Background/Purpose: The impact of bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)‑17F in addition to IL-17A, on structural lesions in patients (pts)…
Abstract Number: 0696 • ACR Convergence 2024
MRI DAVIX Index Is an Imaging Biomarker for Endothelial Damage of Systemic Sclerosis Digital Ulcers
Stefano Di Donato¹, Rebecca Ross², Yassir El-Sherbiny³, Riccardo Bixio⁴, Marco Minerba⁵, Christopher Wasson⁶, Jun Li⁷, Jochen SCHMITZ⁸, Sudha Visvanathan⁹ and Francesco Del Galdo⁶, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, ²Medicine and Health, University of Leeds, Leeds, United Kingdom, ³Nottingham Trent University, Nottingham, United Kingdom, ⁴University of Verona, Verona, Verona, Italy, ⁵1. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, ⁶University of Leeds, Leeds, United Kingdom, ⁷Boehringer Ingelheim, Danbury, CT, ⁸Boehringer-Ingelheim, Ridgefield, CT, ⁹Boehringer-Ingelheim Pharmaceuticals, Ridgefield, CT
Background/Purpose: Circulating endothelial cells (CEC) and their precursors have been shown to correlate to the severity of vascular manifestations in Systemic sclerosis1, such as Digital…

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