Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 2128 • ACR Convergence 2025
Prevalence of Risks and Complications in a Longitudinal International Cohort of Children with Chronic Nonbacterial Osteomyelitis (CNO)
Jessica Kent¹, Eveline Wu², Melissa Oliver³, Sivia Lapidus⁴, Ummusen Akca⁵, Adriel Liau⁶, Pratyush Kore⁷, Ian Muse⁸, Ava Klein⁶, Emily Deng⁶, Iris Hamilton⁶, Haodong Chen⁷, Megan Nguyen⁷, Tianai Li⁹, Avril Wilson⁷, Jasmine Morden⁷, Shima Yasin¹⁰, Aleksander Lenert¹¹, Sara M. Stern¹², Antonella Insalaco¹³, Manuela Pardeo¹⁴, Gabriele Simonini¹⁵, Edoardo Marrani¹⁶, Xing Wang⁶, Bin Huang¹⁷, Leonard Kovallick¹⁸, Natalie Rosenwasser¹⁹, Erin Balay-Dustrude²⁰, Doaa Mosa²¹, Katerina Bouchalova²², Andrea Cabova²³, Jenna Thomason²⁰, Lori Tucker²⁴, Hermann Girschick²⁵, Ronald laxer²⁶, Marinka Twilt²⁷, Georgina Tiller²⁸, Jonathan Akikusa²⁹, Christian Hedrich³⁰, Karen Onel³¹, Fatma Dedeoglu³², Seza Özen³³, Polly Ferguson³⁴ and Yongdong (Dan) Zhao³⁵, ¹Medical College of Wisconsin, Wauwatosa, WI, ²UNC Chapel Hill, Chapel Hill, NC, ³Indiana University, Indianapolis, IN, ⁴Joseph M. Sanzari Children's Hospital, Center for Discovery and Innovation, Hackensack Meridian School of Medicine, Montclair, NJ, ⁵Hacettepe University, Ankara, Turkey, ⁶Seattle Children's Hospital, Seattle, ⁷Seattle Children’s Research Institute, Seattle, ⁸University of Washington, Department of Pediatrics, Seattle Children's Hospital, Seattle, ⁹Seattle Children's Research institute, Seattle, ¹⁰Univeristy of Iowa, Iowa City, ¹¹University of Iowa, Iowa City, IA, ¹²University of Utah, Salt Lake City, UT, ¹³IRCCS Ospedale Pediatrico Bambino Gesu', Rome, Italy, ¹⁴IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy, Rome, Italy, ¹⁵Rheumatology Unit, ERN-ReCONNET center, Meyer Children's Hospital IRCCS, Firenze, Firenze, Italy, ¹⁶University of Florence, Firenze, Italy, ¹⁷Cincinnati Children's Hospital, Cinciannati, OH, ¹⁸The University of North Carolina at Chapel Hil, Chapel Hill, ¹⁹Seattle Children's Hospital, seattle, WA, ²⁰University of Washington, Seattle, WA, ²¹Mansoura University Hospitals, Mansoura City, Egypt, ²²Palacký University Olomouc, Olomouc, Czech Republic, ²³Faculty of Medicine and Dentistry Palacky University Olomouc, Olomouc, Czech Republic, ²⁴BC Children's Hospital, Vancouver, BC, Canada, ²⁵Vivantes Clinic Friedrichshain, Wuerzburg, Germany, ²⁶The Hospital for Sick Children, Toronto, ON, Canada, ²⁷Alberta Children's Hospital, Alberta, Canada, ²⁸Royal Children’s Hospital, Melborne, Australia, ²⁹The Royal Children's Hospital, Parkville, Victoria, Australia, ³⁰University of Liverpool, Liverpool, United Kingdom, ³¹HSS, New York, NY, ³²Boston Children's Hospital, Boston, MA, ³³Hacettepe University Medical Faculty, Ankara, Turkey, ³⁴University of Iowa Carver College of Medicine, Iowa City, IA, ³⁵Seattle Children’s Research Institute, Redmond, WA
Background/Purpose: Chronic nonbacterial osteomyelitis (CNO) is associated with various comorbidities and long-term complications. The CHronic nonbacterial Osteomyelitis International Registry (CHOIR) is a multi-national database that…
Abstract Number: 0716 • ACR Convergence 2025
Utility of Follow-Up Cardiac Magnetic Resonance Imaging In Patients With Eosinophilic Granulomatosis With Polyangiitis
Chelsea Cheng¹, Justine Lafleur-Careau², Navneet Kang¹, Medha Soowamber³ and Christian Pagnoux³, ¹Mount Sinai Hospital, Toronto, Canada, ²Mount Sinai Hospital, Saint-Augustin-de-Desmaures, Canada, ³Mount Sinai Hospital, Toronto, ON, Canada
Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder characterized by asthma, rhinitis, peripheral blood eosinophilia, and necrotizing vasculitis of small vessels. Cardiac…
Abstract Number: 2091 • ACR Convergence 2025
Multiplanar MRI Quantification of Effusion-Synovitis: Reliability and Potential Investigative Utility for Inflammation-Mediated Knee Conditions
Greg Gilles¹, Dagoberto Robles², Luke Grawer³, Nathaniel H. Christiansen⁴, Karim Jayyusi³, Ali Shaikh³, Rongrong Tang⁵, Mihra S. Taljanovic³, Jeffrey Duryea⁶, Edward J. Bedrick⁵ and C. Kent Kwoh⁷, ¹University of Arizona Arthritis Center, The University of Arizona College of Medicine, Tucson, AZ, ²University of Arizona, Tucson, AZ, ³University of Arizona, Tucson, ⁴University of Arizona, Stockton, NJ, ⁵The University of Arizona Arthritis Center, University of Arizona, Tucson, ⁶Brigham and Women’s Hospital, Boston, MA, ⁷The University of Arizona Arthritis Center, University of Arizona, Tucson, AZ
Background/Purpose: Effusion-synovitis (ES) is often seen in knee osteoarthritis (KOA), and MRI-detected ES may serve as a potential imaging biomarker of disease activity, progression, and…
Abstract Number: 0681 • ACR Convergence 2025
Evaluation of Serial Cardiovascular Magnetic Resonance Monitoring and Immunosuppressive Therapy in Predicting Long-Term Outcomes in Systemic Sclerosis
Aïcha Kante¹, Sandra Mghaieth², bertrand Dunogue³, Alice berezne³, Cloé Comarmond¹, Marie-Pierre Revel², Guillaume Chassagnon², Luc Mouthon³ and Benjamin Chaigne³, ¹Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, Assistance Publique Hôpitaux de Paris, INSERM U⁹⁴², Paris, France, ²Radiology Department, Cochin University Hospital, Université Paris Cité, AP-HP, Paris, France, ³Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Cochin University Hospital, Université Paris Cité, AP-HP, Paris, France
Background/Purpose: Systemic sclerosis (SSc) is a connective tissue disease that can manifest as widespread skin and visceral fibrosis, potentially affecting major organs including the heart.…
Abstract Number: 2085 • ACR Convergence 2025
Estimating the Association between Effusion-synovitis and Knee Pain in a Subset of Participants with Radiographic Knee Osteoarthritis: Data from the Osteoarthritis Initiative (OAI)
Dagoberto Robles¹, Greg Gilles², Nathaniel H. Christiansen³, Luke Grawer⁴, Karim Jayyusi⁴, Ali Shaikh⁴, Rongrong Tang⁵, Mihra S. Taljanovic⁴, Jeffrey Duryea⁶, Edward J. Bedrick⁵ and C. Kent Kwoh⁷, ¹University of Arizona, Tucson, AZ, ²University of Arizona Arthritis Center, The University of Arizona College of Medicine, Tucson, AZ, ³University of Arizona, Stockton, NJ, ⁴University of Arizona, Tucson, ⁵The University of Arizona Arthritis Center, University of Arizona, Tucson, ⁶Brigham and Women’s Hospital, Boston, MA, ⁷The University of Arizona Arthritis Center, University of Arizona, Tucson, AZ
Background/Purpose: Even though knee pain is ubiquitous in knee osteoarthritis (KOA) patients, currently there are limited treatment options which are only minimally or moderately efficacious…
Abstract Number: 0852 • ACR Convergence 2025
LEVI-04 Significantly Reduces Bone Marrow Lesions and Symptoms in Knee Osteoarthritis: Results from a Phase II RCT
Simon Westbrook¹, Ali Guermazi² and Philip Conaghan³, ¹Levicept Ltd, Sandwich, United Kingdom, ²Boston University, West Roxbury, MA, ³University of Leeds, Leeds, United Kingdom
Background/Purpose: Bone marrow lesions (BMLs), detectable on MRI as areas of ill-defined high signal intensity on fluid-sensitive sequences, are a common feature of osteoarthritis (OA),…
Abstract Number: 2081 • ACR Convergence 2025
Radiologic surveillance in the Phase II RCT of LEVI-04, a novel neurotrophin-3 inhibitor, in people with knee osteoarthritis: exclusions at screening
Ali Guermazi¹, Philip Conaghan², C Michael Perkins³, Claire Herholdt⁴, Iwona Bombelka⁵ and Simon Westbrook⁶, ¹Boston University, West Roxbury, MA, ²University of Leeds, Leeds, United Kingdom, ³Levicept, Sandwich, United Kingdom, ⁴Levicept Ltd, Ashtead, United Kingdom, ⁵Levicept, Sandwich, Kent, United Kingdom, ⁶Levicept Ltd, Sandwich, United Kingdom
Background/Purpose: LEVI-04 is a first-in-class fusion protein (p75NTR-Fc) that supplements the endogenous p75NTR binding protein, providing analgesia via inhibition of NT-3 activity. Like p75NTR, LEVI-04…
Abstract Number: 0548 • ACR Convergence 2025
Artificial Intelligence in Axial Spondyloarthritis Diagnosis: Integrating Structural and Inflammatory Lesionsfrom Sacrum MRI
Seonyoung Kang¹, Yunseo Kim², Seulkee Lee³, Myung Jin Chung⁴, Hyungjin Kim⁵, Jaejoon Lee⁴, Hakje Yoo⁶ and Hoon-Suk Cha⁴, ¹Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam-gu, Seoul, Republic of Korea, ²Samsung Medical Center, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea, ³Samsung Medical Center, Sunkyunkwan University School of Medicine, Seoul, South Korea, ⁴Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea, ⁵Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ⁶Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea
Background/Purpose: The Assessment of SpondyloArthritis International Society (ASAS) criteria define positive MRI findings based on the presence of bone marrow edema (BME) in the sacroiliac…
Abstract Number: 0224 • ACR Convergence 2024
How Accurate Are Assessments by Local Radiologists of Sacroiliac Joint MRIs in Axial Spondyloarthritis and Psoriatic Arthritis in Routine Clinical Practice?- Evidence from 873 Patients in Five European Countries
Anna EF Hadsbjerg¹, Simon Krabbe², Nora Vladimirova², Adrian Ciurea³, Kristyna Bubova⁴, Monika Gregová⁴, Michael Nissen⁵, Burkhard Moeller⁶, Raphael Micheroli⁷, Susanne Pedersen⁸, Jakub Zavada⁴, Ziga Snoj⁹, Karlo Pintaric⁹, Bjorn Gudbjornsson¹⁰, Ziga Rotar¹¹, iris Eshed¹², Iwona Sudol-Szopinska¹³, Kasper Gosvig¹⁴, Torsten Diekhoff¹⁵, Robert Lambert¹⁶, Manouk de hOoge¹⁷, Helena V G Elmo¹, Merete Hetland¹⁸, Lykke Oernbjerg¹⁹ and Mikkel Ostergaard²⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Righospitalet, Glostrup, Denmark, ²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Righospitalet, Copenhagen, Denmark, ³University Hospital Zurich, Zürich, Switzerland, ⁴Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine Charles University, Prague, Czech Republic, ⁵Geneva University Hospital, Geneva, Switzerland, ⁶Inselspital - University Hospital Bern, Bern, Switzerland, ⁷University Hospital Zurich, Zurich, Switzerland, ⁸Rigshospitalet, København, Denmark, ⁹Institute of Radiology, UMC Ljubljana, Ljubljana, Slovenia, ¹⁰Landspitali University Hospital and University of Iceland, Reykjavik, Iceland, ¹¹University Medical Centre Ljubljana and University of Ljubljana, Ljubljana, Slovenia, ¹²Sheba Medical Center, Tel Hashomer affiliated with School of medicine, Tel Aviv University, Department of Diagnostic Imaging, Tel Aviv, Israel, ¹³Department of Radiology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland, ¹⁴Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark, ¹⁵Charite Universitatsmedizin Berlin, Berlin, Germany, ¹⁶University of Alberta, Edmonton, AB, Canada, ¹⁷Dept. of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium, ¹⁸Rigshospitalet Glostrup and University of Copenhagen, Glostrup, Denmark, ¹⁹Rigshospitalet Glostrup, Glostrup, Hovedstaden, Denmark, ²⁰Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark
Background/Purpose: MRI of the sacroiliac joints (SIJs) is widely used for diagnosing and monitoring patients with spondyloarthritis (SpA). However, local radiologists might be less familiar with…
Abstract Number: 1180 • ACR Convergence 2024
Relationship Between Changes in Physical Activity and Early Onset Knee Osteoarthritis in Individuals After ACL Reconstruction
David Werner¹, Yvonne Golightly¹, Michael Rosenthal¹, Balasrinivasa Sajja¹, Christopher Wichman¹, Melissa Manzer², Matthew Tao¹ and Elizabeth Wellsandt¹, ¹University of Nebraska Medical Center, Omaha, NE, ²Private Practice, Omaha
Background/Purpose: Low physical activity levels are associated with osteoarthritis (OA) development and progression in individuals at risk for OA development. Including both structural and symptomatic…
Abstract Number: 2583 • ACR Convergence 2024
Apremilast Reduces Axial Inflammation in Patients with Psoriatic Arthritis as Assessed by CANDEN MRI Scoring: Results from a Phase 4 Study
Mikkel Ostergaard¹, Walter Maksymowych², Robert Lambert², Mikael Boesen³, Guillermo J. Valenzuela⁴, Michael R. Bubb⁵, Olga Kubassova⁶, Xenofon Baraliakos⁷, Carlo Selmi⁸, Stephen Colgan⁹, Yuri Klyachkin¹⁰, Cynthia Deignan¹¹, Zhenwei Zhou¹¹ and Philip Mease¹², ¹Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, ²University of Alberta, Edmonton, AB, Canada, ³Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, ⁴Guillermo Valenzuela MD PA/ IRIS Rheumatology, Plantation, FL, ⁵University of Florida, Gainesville, FL, ⁶Image Analysis Group, Philadelphia, PA, ⁷Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁸Department of Biomedical Sciences, Humanitas University, Rozzano, Italy, ⁹Amgen, Halton Hills, ON, Canada, ¹⁰Amgen, Lexington, KY, ¹¹Amgen Inc., Thousand Oaks, CA, ¹²Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA
Background/Purpose: Apremilast is an oral phosphodiesterase-4 inhibitor with a unique immunomodulatory mechanism of action and is approved for the treatment of psoriatic arthritis (PsA). Although…
Abstract Number: 0228 • ACR Convergence 2024
Do Imaging Tests Have a Role in Predicting Progression to Rheumatoid Arthritis in People with Clinically Suspect Arthralgia? A Systematic Review & Meta-Analysis
Ankita Gupta¹, Sulaiman Anis² and Paola de Pablo², ¹Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom, ²University of Birmingham, Birmingham, United Kingdom
Background/Purpose: Clinically suspect arthralgia (CSA) has been associated with an increased risk of developing inflammatory arthritis (IA). Subclinical inflammation on imaging tests may help to…
Abstract Number: 1280 • ACR Convergence 2024
Abnormal Cortical Gyrification Patterns in Adolescents with Childhood-onset SLE: Early Associations with Perceived Fatigue
Diana Valdes Cabrera¹, Tala El Tal², Santiago Arciniegas¹, Oscar Mwizerwa³, Asha Jeyanathan³, Lawrence Ng¹, Paris Moaf¹, Joanna Law⁴, Sarah Mossad⁵, Birgit Ertl-Wagner¹, Ann Yeh¹, Helen Branson¹, Adrienne Davis⁶, Linda Hiraki¹, Deborah Levy¹, Busi Zapparoli⁷, Ashley Danguecan⁸ and Andrea Knight⁹, ¹The Hospital for Sick Children, Toronto, ON, Canada, ²The Hospital For Sick Children & Children's Hospital of Eastern Ontario (CHEO), Ottawa, ON, The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, ³The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Neurosciences and Mental Health, Research Institute, Toronto, ON, Canada, ⁴The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, ⁵Hospital for Sick Children, Toronto, ON, Canada, ⁶Division of Pediatric Emergency Medicine, Department of Pediatrics, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ⁷The Hospital for Sick Children, Etobicoke, ON, Canada, ⁸The Hospital for Sick Children, Department of Psychology, University of Toronto, Toronto, ON, Canada, ⁹Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada
Background/Purpose: Fatigue and brain fog are early complaints in adolescents with childhood-onset SLE (cSLE), who experience disease onset during a critical period of brain development.…
Abstract Number: 2650 • ACR Convergence 2024
Extent of Vascular Inflammation on Cranial Vessel Wall MRI and Ophthalmic Complications in Giant Cell Arteritis
David Yang¹, Quy Cao², Fang Liu², Tara McWilliams², Ryan Rebello³, Madhura Tamhankar², Shubhasree Banerjee², Rui Liang², Robert Kurtz², Joshua Baker¹, Naomi Amudala², Zhaoyang Fan⁴, Jae Song², Peter Merkel¹, Jeffrey Morris² and Rennie Rhee¹, ¹University of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, ³St Joseph’s Hospital and McMaster University, Hamilton, ON, Canada, ⁴University of Southern California, Los Angeles, CA
Background/Purpose: There is a need for measures of disease severity for giant cell arteritis (GCA), which may enable identification of high-risk subgroups (e.g., ophthalmic complications)…
Abstract Number: 0230 • ACR Convergence 2024
Spine and Sacroiliac Joint Involvement in Newly Diagnosed Patients with Inflammatory Bowel Disease – Clinical and MRI Findings from a Population-Based Cohort Study
Nora Vladimirova¹, Jakob Møller², Mohamed Attauabi², Gorm Madsen³, Lene Terslev⁴, Charlotte Wiell⁵, Viktoria Fana⁶, Sanja Bay Hansen³, Hartwig Siebner³, Jakob Seidelin², Flemming Bentsen³, Kasper Gosvig⁷, Johan Burisch³ and Mikkel Ostergaard⁸, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Righospitalet, Copenhagen, Denmark, ²Herlev and Gentofte Hospital, copenhagen, Denmark, ³Hvidovre Hospital, copenhagen, Denmark, ⁴Rigshospitalet-Glostrup & COPECARE, Glostrup, Denmark, ⁵Rigshospitalet-Glostrup, Copenhagen, Denmark, ⁶Rigshospitalet-Glostrup, Glostrup, Denmark, ⁷Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark, ⁸Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark
Background/Purpose: In patients with inflammatory bowel disease (IBD), coexistence of spondyloarthritis (SpA), the most common extraintestinal manifestation, is associated with poor outcomes and impaired quality…

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