ACR Meeting Abstracts

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Abstracts tagged "Magnetic resonance imaging (MRI)"

  • Abstract Number: 1854 • ACR Convergence 2025

    Resting-State Functional Magnetic Resonance Imaging Analysis Revealed Altered Functional Connectivity Associated with Fatigue in Systemic Lupus Erythematosus

    Yujie Song1, Nobuya Abe1, Yuichiro Fujieda2, Kodai Sakiyama1, Yuta Inoue1, Kenichi Miyamoto1, Kazuro Kamada1, Yotaro Oki1, Maria Tada1, Shuhei Takeyama1, Ryo Hisada2, Michihito Kono2 and Tatsuya Atsumi2, 1Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 2Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

    Background/Purpose: Fatigue is one of the most frequent constitutional symptoms in systemic lupus erythematosus (SLE), usually accompanied with impaired quality of life. Resting-state functional magnetic…
  • Abstract Number: 2625 • ACR Convergence 2025

    Early Detection of Knee Osteoarthritis – The Role of a Composite Disease Activity Metric: Data from the Osteoarthritis Initiative

    Julieann Patarini1, Timothy McAlindon2, Jonggyu Baek1, Emily Kirillov3, Nhung Vo3, Michael Richard3, Ming Zhang4, Matthew Harkey5, Grace Lo6, Shao-Hsien Liu1, Kate Lapane1, Charles Eaton7, James Mackay8 and Jeffrey Driban9, 1UMass Chan Medical School, Worcester, MA, 2UMass Chan School of Medicine, Arlington, MA, 3Tufts Medical Center, Boston, MA, 4Boston University, Westford, MA, 5Michigan State University, East Lansing, MI, 6Baylor College of Medicine / MEDVAMC, Houston, TX, 7Brown University, Pawtucket, RI, 8University of Cambridge; Norwich Medical School, San Diego, CA, 9University of Massachusetts Chan Medical School, Marlborough, NH

    Background/Purpose: Bone marrow lesions (BMLs) and effusion-synovitis are frequent and dynamic disease processes detected from early- to late-stage knee OA. These processes are associated with…
  • Abstract Number: 0323 • ACR Convergence 2025

    Automated Effusion-Synovitis Volume is Prognostic and Responsive to Knee Osteoarthritis Progression: Data from the Osteoarthritis Initiative

    Jeffrey Driban1, Kate Lapane2, Shao-Hsien Liu2, Jonggyu Baek2, Grace Lo3, Matthew Harkey4, Charles Eaton5, James Mackay6, Timothy McAlindon7, Mohammad Chowdhury8, Zhen Cao9, Juan Shan10 and Ming Zhang11, 1University of Massachusetts Chan Medical School, Marlborough, NH, 2UMass Chan Medical School, Worcester, MA, 3Baylor College of Medicine / MEDVAMC, Houston, TX, 4Michigan State University, East Lansing, MI, 5Brown University, Pawtucket, RI, 6University of Cambridge; Norwich Medical School, San Diego, CA, 7UMass Chan School of Medicine, Arlington, MA, 8Pace University, New York City, NY, 9Boston University, Boston, MA, 10Pace University, New York, NY, 11Boston University, Westford, MA

    Background/Purpose: Semi-quantitative and semi-automated quantitative measurements of effusion-synovitis (ES) are prognostic for knee OA progression. Changes in these metrics relate to changes in knee pain.…
  • Abstract Number: 1937 • ACR Convergence 2025

    Does Combining Standard MRI-Based Scores with Radiographic Trabecular Bone Texture Biomarkers Improve Predictive Performance for Radiographic Knee Osteoarthritis Progression?

    Ahmad Almhdie-Imjabbar1, Saida Daroussi2, Daniela Herrera3, Hechmi Toumi2 and Eric Lespessailles4, 1University Hospital Center of Orleans, Orleans, France, 2PRIMMO- University Hospital Center of Orleans, Orleans, France, 3PRIMMO- University Hospital Center of Orleans, Olreans, France, 4CHU Orléans, Orléans, France

    Background/Purpose: Knee osteoarthritis (KOA) is a major cause of disability worldwide, particularly impacting the elderly and obese population. Radiographic trabecular bone texture (TBT) is demonstrated…
  • Abstract Number: 2635 • ACR Convergence 2025

    Differences in structural lesions of the spine between patients with early axSpA and non-axSpA chronic back pain: 2-year results of the SPACE Cohort

    Gizem Ayan1, Liese de Bruin2, Miranda van Lunteren2, Manouk de Hooge3, Ana Bento da Silva2, Mary Lucy Marques4, Monique Reijnierse5, Victoria Navarro-Compan6, Marleen van de sande7, Inger Jorid Berg8, Roberta Ramonda9, Sofia Exarchou10, Désirée Van Der Heijde2, Floris A. van Gaalen2 and Sofia Ramiro11, 1Ankara Research and Training Hospital, Ankara, Turkey, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, 4Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; and Coimbra Local Health Unit, Coimbra, Portugal, 5Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, 6Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 7The Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Amsterdam, Netherlands, 8Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 9Rheumatology Unit-DIMED-University of Padova ITALY, Padova, Padua, Italy, 10Lund University, Åkarp, Skane Lan, Sweden, 11Leiden University Medical Center, Bunde, Netherlands

    Background/Purpose: The difference in spinal structural lesions and their progression over time between chronic back pain (CBP) patients with and without early axSpA is unknown.…
  • Abstract Number: 0390 • ACR Convergence 2025

    Radiographic Assessment in Juvenile Spondyloarthritis: Evaluating the axJSpA Criteria Using Radiographs Alone Versus MRI

    David M. Biko1, Nancy A. Chauvin2, Michael Francavilla3, Nele Herregods4, Walter P. Maksymowych5, Robert G. W. Lambert6, Timothy Brandon1, Ozgur Kasapcopur7, Mehmet YILDIZ8, Hemalatha Srinivasalu9 and Pamela Weiss10, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2The Cleveland Clinic, Hummelstown, PA, 3Department of Pediatric Radiology, Children’s Hospital Philadelphia, Philadelphia, PA, 4Ghent University Hospital, Ghent, Belgium, 5Department of Medicine, University of Alberta, 568 Heritage Building, Edmonton, AB, Canada, 6University of Alberta, Department of Radiology & Diagnostic Imaging, Edmonton, AB, Canada, 7Istanbul University-Cerrahpasa, Cerrahpasa Medical School, istanbul, Turkey, 8Istanbul University-Cerrahpasa Department of Pediatric Rheumatology, Istanbul, Turkey, 9Children's National Hospital, Washington, DC, 10Childrens Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Radiographs are neither sensitive nor reliable for assessing axial disease in juvenile spondyloarthritis (JSpA), though they are still used in some settings due to…
  • Abstract Number: 1945 • ACR Convergence 2025

    Significance of Finger Joint Tenderness With or Without Swelling in Relation to MRI, Ultrasound, and X-Ray Findings in Psoriatic Arthritis_Final results

    Victoria Furer1, iris Eshed2, Moshe Iluz1, Ori Elkayam3 and Ari Polachek4, 1Tel-Aviv Medical Center, Tel-Aviv, Israel, 2Department of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer affiliated with School of Medicine, Tel Aviv University, Tel Aviv, Israel, 3Tel Aviv medical center, Tel Aviv, Israel, 4Rheumatology Institute of Beilinson Hospital, Petah Tikva, Israel

    Background/Purpose: Musculoskeletal involvement in psoriatic arthritis (PsA) affects both articular and extra-articular structures, presenting as inflammatory and structural lesions. The relationship between tender and/or swollen…
  • Abstract Number: 2677 • ACR Convergence 2025

    Quantified Imaging Response at the Sacroiliac Joints to TNF-Inhibitor Therapy in Youth with Axial Disease

    Timothy Brandon1, Rui Xiao2, Daniel Lovell3, Edward Oberle4, Matthew Stoll5, Nancy A. Chauvin6, Michael Francavilla7, Walter P. Maksymowych8 and Pamela Weiss9, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Nationwide Children's Hospital, Columbus, OH, 5University of Alabama at Birmingham, Birmingham, AL, 6The Cleveland Clinic, Hummelstown, PA, 7Department of Pediatric Radiology, Children’s Hospital Philadelphia, Philadelphia, PA, 8Department of Medicine, University of Alberta, 568 Heritage Building, Edmonton, AB, Canada, 9Childrens Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: This study assessed the timeline for the resolution of inflammation, changes in structural lesions at the sacroiliac joints (SIJ), and their correlation with patient-reported…
  • Abstract Number: 0656 • ACR Convergence 2024

    Lupus Myocarditis: Clinical Characteristics, Cardiac Magnetic Resonance Imaging Findings and Outcomes

    María del Carmen Zamora-Medina1, Erik Cimé-Aké2, Emilio G. Lazarini2, Wallace Rafael A. Muñoz-Castañeda3 and Hilda Fragoso-Loyo2, 1Instituto Nacional de Perinatología "Isidro Espinoza de los Reyes". Rheumatology Department, Mexico City, Distrito Federal, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Immunology and Rheumatology Department, Mexico City, Mexico, 3Hospital Medica Sur. Rheumatology Department, Mexico City, Distrito Federal, Mexico

    Background/Purpose: Limited information about lupus myocarditis (LM) comes from small case series. The aim of our study is to describe and compare clinical characteristics, cardiac…
  • Abstract Number: 1478 • ACR Convergence 2024

    Associations Between Clinical Characteristics and Screening MRI Findings: Exploratory Analysis of the Ongoing Phase 4, Multicenter, Randomized, Controlled STAR Study of Biologic-Naïve Patients with PsA with MRI-Confirmed Axial Involvement

    Xenofon Baraliakos1, Paul Bird2, Atul Deodhar3, Dafna Gladman4, Philip S. Helliwell5, Denis Poddubnyy6, Arthur Kavanaugh7, Mikkel Ostergaard8, Enrique R. Soriano9, Lai-shan Tam10, Soumya Chakravarty11, Evan Leibowitz12, Cinty Gong13, Stephen Xu14, Thomas Fuerst15, Nadeem Saeed16, Robert Landewé17 and Philip Mease18, 1Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 2University of New South Wales, Randwick, NSW, Sydney, New South Wales, Australia, 3Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 4University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 5Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK, Leeds, United Kingdom, 6Charite-Universitatsmedizin Berlin, Berlin, Germany, 7University of California San Diego, La Jolla, CA, 8Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, 9Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 10The Chinese University of Hong Kong, New Territories, Hong Kong, 11Janssen Scientific Affairs, LLC, Horsham/ Drexel University College of Medicine, Philadelphia, Horsham, PA, 12Janssen Scientific Affairs, LLC, Fair Lawn, NJ, 13Janssen Scientific Affairs, Horsham, PA, 14Janssen Research & Development, LLC, Spring House, PA, USA, Spring House, PA, 15Clario, San Mateo, CA, 16Clario, San Mateo, 17Amsterdam University Medical Center, Meerssen, Netherlands, 18Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA

    Background/Purpose: Patients (pts) with PsA can develop axial inflammation in the SI joints (SIJs) and/or spine. Although validated classification criteria for axial spondyloarthritis exist, established…
  • Abstract Number: 0683 • ACR Convergence 2024

    Prognostic Value of Systemic Sclerosis-associated Primary Heart Involvement

    Caya Gharibian1, Vanessa Lupi1, Alexander Gotschy1, Mike Becker2, Rucsandra Dobrota1, Muriel Elhai3, Sinziana Muraru1, Suzana Jordan1, Anna-Maria Hoffmann-Vold4, Oliver Distler5, Robert Manka1, Cosimo Bruni1 and Carina Mihai1, 1University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 3University Hospital zurich, Zürich, Switzerland, 4Oslo University Hospital, Oslo, Norway, 5Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Zurich, Switzerland

    Background/Purpose: A definition of primary heart involvement (pHI) in systemic sclerosis (SSc) was recently developed (Bruni C et al. J Scleroderma Relat Disord. 2022;7:24-32). Cardiac…
  • Abstract Number: 1635 • ACR Convergence 2024

    Magnetic Resonance Imaging for Therapy Monitoring in Giant Cell Arteritis – Impact on Disease Management

    Matthias Froehlich1, Michael Gernert2, Marc Schmalzing3, Patrick-Pascal Strunz4, Hanna Labinsky5, Thorsten A. Bley6 and Konstanze V. Guggenberger6, 1Uniklinikum Wuerzburg, Medizinische Klinik II, Wuerzburg, Germany, 2Medicine II, Division Rheumatology/Clinical Immunology, University Hospital of Wuerzburg, Wuerzburg, 3University Hospital Wuerzburg, Würzburg, Germany, 4University hospital of Wuerzburg, Wuerzburg, Germany, 5University Hospital Würzburg, Wuerzburg, Germany, 6University Hospital Würzburg, Würzburg, Germany

    Background/Purpose: Imaging techniques such as magnetic resonance imaging (MRI) are a cornerstone for the diagnosis of giant cell arteritis (GCA). In the further course of…
  • Abstract Number: 0689 • ACR Convergence 2024

    Arrhythmic Burden, Myocardial Markers, and Long-term Survival in Distinct Cardiac Magnetic Resonance Subsets of Systemic Sclerosis

    Silvia Laura Bosello1, Enrico De Lorenzis2, Giacomo De Luca3, Antonio Tonutti4, veronica Batani5, Pier Giacomo Cerasuolo6, Gerlando Natalello7, Lucia Lanzo6, Gabriella Alonzi6, Silvia Fiore6, Stefano Di Murro6, Andrea Zoli6, Valentina Boni6, Riccardo Marano8, Francesca Augusta Gabrielli9, Francesco Del Galdo10, Dan Knight11, Vivek Muthurangu11, Christopher Denton12, Maria De Santis4, Marco Matucci Cerinic5 and Maria Antonietta D'Agostino13, 1Unit of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, 2Catholic University of the Sacred Heart, Roma, Rome, Italy, 3Vita-Salute San Raffaele University & IRCCS San Raffaele Hospital, Milan, Milan, Italy, 4Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy, 5Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy, 6Division of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 7Division of Rheumatology - Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, 8Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy, 9Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 10University of Leeds, Leeds, United Kingdom, 11UCL Department of Cardiac MRI, University College London (Royal Free Campus), London, United Kingdom, 12University College London, Northwood, United Kingdom, 13Division of Rheumatology, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy

    Background/Purpose: Cardiac involvement in Systemic Sclerosis (SSc) is widely recognized as heterogeneous and, when clinically evident, it is associated with a poor prognosis. Recently, five…
  • Abstract Number: 1757 • ACR Convergence 2024

    Bimekizumab Treatment Resulted in Improvements in MRI Inflammatory and Structural Lesions in the Sacroiliac Joints of Patients with Axial Spondyloarthritis: 52-Week Results and Post Hoc Analyses from Two Phase 3 Studies

    Walter Maksymowych1, Sofia Ramiro2, Denis Poddubnyy3, Xenofon Baraliakos4, Robert Lambert1, Ute Massow5, Thomas Vaux6, Chetan Prajapati6, Alexander Marten5, Natasha de Peyrecave7 and Mikkel Ostergaard8, 1University of Alberta, Edmonton, AB, Canada, 2Leiden University Medical Center, Bunde, Netherlands, 3Charite-Universitatsmedizin Berlin, Berlin, Germany, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 5UCB Pharma, Monheim am Rhein, Germany, 6UCB Pharma, Slough, United Kingdom, 7UCB Pharma, Brussels, Belgium, 8Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark

    Background/Purpose: The impact of bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)‑17F in addition to IL-17A, on structural lesions in patients (pts)…
  • Abstract Number: 0696 • ACR Convergence 2024

    MRI DAVIX Index Is an Imaging Biomarker for Endothelial Damage of Systemic Sclerosis Digital Ulcers

    Stefano Di Donato1, Rebecca Ross2, Yassir El-Sherbiny3, Riccardo Bixio4, Marco Minerba5, Christopher Wasson6, Jun Li7, Jochen SCHMITZ8, Sudha Visvanathan9 and Francesco Del Galdo6, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, 2Medicine and Health, University of Leeds, Leeds, United Kingdom, 3Nottingham Trent University, Nottingham, United Kingdom, 4University of Verona, Verona, Verona, Italy, 51. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 6University of Leeds, Leeds, United Kingdom, 7Boehringer Ingelheim, Danbury, CT, 8Boehringer-Ingelheim, Ridgefield, CT, 9Boehringer-Ingelheim Pharmaceuticals, Ridgefield, CT

    Background/Purpose: Circulating endothelial cells (CEC) and their precursors have been shown to correlate to the severity of vascular manifestations in Systemic sclerosis1, such as Digital…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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