ACR Meeting Abstracts

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Abstracts tagged "Magnetic resonance imaging (MRI)"

  • Abstract Number: 2148 • ACR Convergence 2025

    Initial MRI Findings as Predictors of Disease Phenotype in Juvenile Dermatomyositis: A Comparative Study of Myositis Specific Antibodies NXP2-Positive and Myositis Specific Antibody-Negative Patients in a Large Tertiary Hospital

    Juan Torres Sanchez1, Pritish Bawa2, Andrea Ramirez1, MaiLan Nguyen3, Amit Thakral4, Xiaofan Huang1, J Herman Kan2 and Marietta De Guzman1, 1Baylor College of Medicine, Houston, TX, 2Texas Childrens Hospital, Houston, TX, 3Baylor College of Medicine, Austin, TX, 4Texas Children’s Hospital, Houston, TX

    Background/Purpose: Juvenile dermatomyositis (JDM) is the most common idiopathic inflammatory myopathy of childhood, characterized by proximal muscle weakness and distinctive cutaneous findings. Magnetic resonance imaging…
  • Abstract Number: 1239 • ACR Convergence 2025

    JAK inhibition appears to alter clinical and neurobiological markers of nociplastic pain in rheumatoid arthritis: a 7T MRI Brain study

    Kristian Stefanov1, Andrew McGucken1, Maxine Arnott1, Tyrone Lau1, Norah Aldehmi1, Vinod Kumar2, Neil McKay3, James Dale4, Lindsay Robertson5, James Brock1, Flavia Sunzini6 and Neil Basu7, 1University of Glasgow, Glasgow, United Kingdom, 2NHS Tayside, Dundee, United Kingdom, 3NHS Lothian, Edinburgh, United Kingdom, 4NHS Lanarkshire, Wishaw, United Kingdom, 5NHS Grampian, Aberdeen, United Kingdom, 6Glasgow University, Glasgow, United Kingdom, 7Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Pain remains a prevalent and highly impactful issue for people with rheumatoid arthritis (RA). Among modern day targeted therapies, the janus kinase (JAK) inhibitors…
  • Abstract Number: 2154 • ACR Convergence 2025

    Whole-Body MRI Findings in a Cohort of  Children with Chronic Nonbacterial Osteomyelitis

    Mara Rodriguez1, Maurice Davenport Munoz2, Kiery Braithwaite3, Lori Ponder4, Kelly Rouster-Stevens5, Solveig Argeseanu Cunningham6 and Sampath Prahalad7, 1Emory University School of Medicine / Children's Healthcare of Atlanta, Atlanta, GA, 2Emory University School of Medicine, Pediatrics, Atlanta, 3Children's Healthcare of Atlanta, Atlanta, GA, 4Emory University, Atlanta, GA, 5Emory University/Children's Healthcare of Atlanta, Peachtree Corners, GA, 6Emory Rollins School of Public Health Department of Global Health, Atlanta, GA, 7Emory + Children's Pediatric Institute, Atlanta, GA

    Background/Purpose: Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disorder characterized by multifocal, sterile bone inflammation in childhood. Whole-body magnetic resonance imaging (WB-MRI) allows for…
  • Abstract Number: 1414 • ACR Convergence 2025

    Multidimensional Assessment to Differentiate Early Psoriatic Arthritis from Cutaneous Psoriasis

    Eugeniu Russu1, Victor Cazac2, Mircea Betiu3, Alesea Nistor3 and Liliana Groppa4, 1"Nicolae Testemitanu" State Medical and Pharmaceutical University; ”Timofei Moșneaga” Republican Clinical Hospital, Chisinau, Moldova, 2Norwalk Hospital, Nuvance Health, Connecticut, 3State Medical and Pharmaceutical University ”Nicolae Testemițanu”, Chisinau, Chisinau, Moldova, 4State Medical and Pharmaceutical University ”Nicolae Testemițanu”, Chisinau, Moldova

    Background/Purpose: Psoriatic arthritis (PsA) develops in ~20-30% of psoriasis patients. However, early PsA diagnosis is challenging due to heterogeneous, subtle symptoms and overlap with psoriasis…
  • Abstract Number: 2541 • ACR Convergence 2025

    Development of Severity Classification Criteria for Introduction of Infliximab for Chronic Pogressive Neuro-Behçet’s Disease

    Shunsei Hirohata1, Hirotoshi Kikuchi2, Tetsuji Sawada3, Toshihiro Tono4, Mitsuhiro Takeno5 and Izumi Kawachi6, 1Nobuhara Clinic, Tokyo, Japan, 2Teikyo University School of Medicine, 3-12-1 ????????????1308, Japan, 3Tokyo Medical University, Tokyo, Japan, 4Kitasato University School of Medicine, Kanagawa, Japan, 5Nippon Medical School Musashi Kosugi Hospital, Kawasaki, Japan, 6Niigata University Graduate School of Medicine and Dental Sciences and Niigata University Brain Institute, Niigata, Japan

    Background/Purpose: Chronic progressive neuro-Behçet’s disease (CPNB) is characterized by progressive deterioration leading to disability and death. It has been appreciated that methotrexate (MTX) has beneficial…
  • Abstract Number: 0116 • ACR Convergence 2025

    Cerebral small vessel disease in antiphospholipid syndrome: subtypes and total burden of cSVD on MRI

    Chun Li1, Jianping Guo2, Yangyi Fan1, Yu Kang1 and Xiaodan Hu1, 1Peking University People's Hospital, Beijing, China (People's Republic), 2Peking University People's Hospital, Beijing, Beijing, China

    Background/Purpose: Cerebrovascular diseases are common and severe neurological complications in antiphospholipid syndrome (APS). However, few studies focused on cerebral small vessel disease (cSVD) in APS.…
  • Abstract Number: 1466 • ACR Convergence 2025

    Impact of Bimekizumab on Spinal MRI Inflammation and Structural Lesions in Patients with Radiographic Axial Spondyloarthritis: 2-Year CANDEN Scoring Results from a Phase 3 Study and Its Open-Label Extension

    Walter P. Maksymowych1, Robert G. W. Lambert2, Victoria Navarro-Compan3, Xenofon Baraliakos4, Jason Coarse5, Natasha de Peyrecave6 and Mikkel Ostergaard7, 1Department of Medicine, University of Alberta, 568 Heritage Building, Edmonton, AB, Canada, 2University of Alberta, Department of Radiology & Diagnostic Imaging, Edmonton, AB, Canada, 3Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 4Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 5UCB, Morrisville, NC, 6UCB, Brussels, Belgium, 7Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, and Copenhagen Center for Arthritis Research, Center for Rheumatology, Rigshospitalet, Glostrup, Denmark

    Background/Purpose: Spinal inflammation and structural progression are key features of radiographic axial spondyloarthritis (r-axSpA).1 Canada-Denmark (CANDEN) scoring enables anatomical-based assessments of MRI inflammatory and structural…
  • Abstract Number: 2614 • ACR Convergence 2025

    Impact of Vagus Nerve-Mediated Neuroimmune Modulation on structural joint damage using Gd-MRI RAMRIS imaging in Biologic-Experienced Patients with Rheumatoid Arthritis

    Charles Peterfy, MD, PhD1, John Tesser2, Yaakov Levine3, Melissa Evangelista4, Vibeke Strand5, Michael Weinblatt6 and David Chernoff7, 1Spire Sciences, Inc., Boca Raton, FL, 2Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, 3SetPoint Medical, Valencia, CA, 4SetPoint Medical Corporation, Valencia, CA, 5Stanford University School of Medicine, Palo Alto CA, Portola Valley, CA, 6Brigham and Women's Hospital/ Harvard Medical School, Waban, MA, 7SetPoint Medical, Sausalito, CA

    Background/Purpose: Previously reported results from RESET-RA (ClinicalTrials.gov, NCT04539964) showed neuroimmune modulation via electrical stimulation of the left vagus nerve using an implantable device to treat…
  • Abstract Number: 0234 • ACR Convergence 2024

    MRI of Sacroiliac Joints: Is Contrast Necessary for the Detection of Sacroiliitis?

    Damira Sereda1, Arun Venkataraman1, Harlan Stock1 and Andras Perl2, 1SUNY Upstate Medical University, Syracuse, NY, 2SUNY, Syracuse, NY

    Background/Purpose: Spondyloarthropathy (SpA) encompasses several conditions, such as ankylosing spondylitis, psoriatic arthritis, reactive arthritis, arthritis linked with inflammatory bowel disease, and undifferentiated spondyloarthritis [1]. Sacroiliitis…
  • Abstract Number: 1442 • ACR Convergence 2024

    Relationship Between Degenerative Lesions over Time in Axial Spondyloarthritis: 10-year Follow-up of the DESIR Cohort

    Laura Pina Vegas1, Floris van Gaalen2, Miranda van Lunteren3, Damien Loeuille4, Caroline Morizot5, Esther Newsum6, Pascal Claudepierre7, Alain SARAUX8, Antoine Feydy9, Monique Reijnierse1, Desiree van der Heijde10 and Sofia Ramiro11, 1Leiden University Medical Center, Leiden, Netherlands, 2LUMC, Leiden, Zuid-Holland, Netherlands, 3Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, 4Phd, Nancy Vandoeuvre, Lorraine, France, 5Nancy University hospital, Nancy, France, 6Nij Smellinghe, Drachten, Netherlands, 7CHU Henri Mondor, AP-HP/EpiDermE, UPEC, Créteil, France, 8CHU Brest, Brest, France, 9CHU Cochin, AP-HP, Paris, France, 10Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 11Leiden University Medical Center, Bunde, Netherlands

    Background/Purpose: Spinal degenerative lesions (DLs) are commonly seen/reported in radiographs and MRI in axSpA. However, the relationship between the different DLs over time has not…
  • Abstract Number: 0387 • ACR Convergence 2024

    Absolute Agreement and Inter-rater Reliability of a Web-based Standardized Scoring Tool for Magnetic Resonance Images from Children with Chronic Nonbacterial Osteomyelitis (CNO) Amongst Radiologists

    Farzana Nuruzzaman1, T. Shawn Sato2, Jennifer Stimec3, Ramesh S. Iyer4, Andrew Carbert5, Joel Paschke5, Lauren Potts6, Xiaoyue Zhang7, Walter Maksymowych8, Polly Ferguson9 and Yongdong (Dan) Zhao10, and CARRA CRMO Workgroup, 1Stony Brook Children's Hospital, Stony Brook, NY, 2University of Iowa, Iowa City, 3Hospital for Sick Children, Toronto, ON, Canada, 4Seattle Children's Hospital, Seattle, WA, 5CARE Arthritis, Edmonton, AB, Canada, 6Artist, Long Beach, CA, 7Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, 8University of Alberta, Edmonton, AB, Canada, 9University of Iowa Carver College of Medicine, Iowa City, IA, 10University of Washington, Redmond, WA

    Background/Purpose: The web-based ChRonic nonbacterial Osteomyelitis Magnetic Resonance Imaging Scoring (CROMRIS) portal was developed to assess specific features of bone and soft tissue inflammation in…
  • Abstract Number: 1443 • ACR Convergence 2024

    Natural Course of Degenerative Lesions of the Spine on Radiographs and MRI in Axial SpondyloarthritisFollowed 10 Years in the DESIR Cohort

    Laura PINA VEGAS1, Miranda van Lunteren2, Damien Loeuille3, Caroline Morizot4, Esther Newsum5, Sofia Ramiro6, Floris van Gaalen7, Alain SARAUX8, Pascal Claudepierre9, Antoine Feydy10, Desiree van der Heijde11 and Monique Reijnierse1, 1Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, 3Phd, Nancy Vandoeuvre, Lorraine, France, 4Nancy University hospital, Nancy, France, 5Nij Smellinghe, Drachten, Netherlands, 6Leiden University Medical Center, Bunde, Netherlands, 7LUMC, Leiden, Zuid-Holland, Netherlands, 8CHU Brest, Brest, France, 9CHU Henri Mondor, AP-HP/EpiDermE, UPEC, Créteil, France, 10CHU Cochin, AP-HP, Paris, France, 11Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands

    Background/Purpose: Radiographs and MRI are the two imaging techniques often used to assess structural lesions in axial spondyloarthritis (axSpA). A high prevalence of degenerative lesions…
  • Abstract Number: 0401 • ACR Convergence 2024

    Biologic Abatement and Capturing Kids Outcomes and Flare Frequency in Juvenile Spondyloarthritis: Baseline Characteristics and Enrollment

    Cora Sears1, Cassandra Muir1, Timothy Brandon1, Polly Ferguson2, Colleen Correll3, Margalit Rosenkranz4, Kevin Baszis5, Tzielan Lee6, Edward Oberle7, Matthew Stoll8, Kathryn Cook9, Eyal Muscal10, Hemalatha Srinivasalu11, Daniel Lovell12, Sampath Prahalad13, Michal Cidon14, Evan Mulvihill15, Marisa Klein-Gitelman16, Daniel Kingsbury17, Jennifer Cooper18, Natalie Rosenwasser19, Erin Treemarcki20, Joyce Chang21, Stacey Tarvin22, Heather Walters23, Michael Shishov24, Lisa Buckley25, Mary Toth26, Ashley Cooper27, Rui Xiao28, Emily Neu29, Melanie Kohlheim30, Jenny Leal31, Kweli Archie32, English Holland33, Miles Holland34, Aamena Hameed35, Asad Khan36, Lynn Murphy37, Sean Murphy38, Justin Neu29, Rachel Richmond39, Dylan Suplee40, Theresa Suplee41, Dawn Wiley42 and Pamela Weiss43, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Iowa Carver College of Medicine, Iowa City, IA, 3University of Minnesota, Minneapolis, MN, 4UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 5Washington Univ in St. Louis School of Medicine, St Louis, MO, 6Stanford University School of Medicine, Palo Alto, CA, 7Nationwide Children's Hospital, Columbus, OH, 8University of Alabama at Birmingham, Birmingham, AL, 9Akron Children's Hospital, Akron, OH, 10Baylor College of Medicine, Houston, TX, 11Children's National Hospital, Washington, DC, 12Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 13Emory + Children's Pediatric Institute, Atlanta, GA, 14Children's Hospital of Los Angeles, Los Angeles, CA, 15Nemours/A.I.duPont Hospital for Children, Wilmington, DE, 16Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 17Legacy Health, Portland, OR, 18University of Colorado/Children's Hospital Colorado, Aurora, CO, 19Seattle Children's Hospital, Seattle, WA, 20University of Utah, Salt Lake City, UT, 21Boston Children's Hospital, Boston, MA, 22Indiana University School of Medicine, Indianapolis, IN, 23Northwell Health, New Hyde Park, NY, 24Phoenix Children's Hospital, Phoenix, AZ, 25Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, 26Nemours Foundation, Orlando, FL, 27Children's Mercy Kansas City, Kansas City, MO, 28University of Pennsylvania, Philadelphia, PA, 29Parent Partner, Sidney, OH, 30Parent Partner, Granville, OH, 31Parent Partner, Columbus, OH, 32Parent Partner, Philadelphia, PA, 33Parent Partner, Williamsburg, VA, 34Patient Partner, Williamsburg, VA, 35Parent Partner, Franklin Park, NJ, 36Patient Partner, Franklin Park, NJ, 37Parent Partner, Haddon Heights, NJ, 38Patient Partner, Haddon Heights, NJ, 39Parent Partner, Albuquerque, NM, 40Patient Partner, Maple Shade, NJ, 41Parent Partner, Maple Shade, NJ, 42Parent Partner, Downingtown, PA, 43Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Inactive disease is the goal for youth with spondyloarthritis (SpA).  Many patients are interested in stopping medications after inactive disease is achieved. The risk…
  • Abstract Number: 1445 • ACR Convergence 2024

    Systematic Characterization of MRI Lesions Per ASAS Definitions in the Sacroiliac Joints of Patients with Axial Spondyloarthritis and Comparisons Among Subgroups with Psoriasis, Iritis, Colitis, AxSpA Alone, and Matched Back Pain Controls

    Ulrich Weber1, Susanne Pedersen2, Ozun Bayindir Tsechelidis3, Robert Lambert4, Joel Paschke5, Stephanie Wichuk4 and Walter Maksymowych4, 1Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 2Rigshospitalet, København, Denmark, 3Ottawa University, Ottawa, ON, Canada, 4University of Alberta, Edmonton, AB, Canada, 5CARE Arthritis, Edmonton, AB, Canada

    Background/Purpose: There is limited information on the frequency and topographical distribution of MRI lesions in the sacroiliac joints (SIJ) of patients with axSpA according to…
  • Abstract Number: 0574 • ACR Convergence 2024

    14-3-3 Eta (η) Auto-Antibody as a Diagnostic Marker in Axial Spondyloarthritis: A Longitudinal Study

    Anthony Marotta1, Walter Maksymowych2, Stephanie Wichuk2 and Navneet Sidhu1, 1Augurex Life Sciences Corp, Vancouver, BC, Canada, 2University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Diagnosis of axial spondyloarthritis (AxSpA) is challenging and often delayed primarily due to the lack of sensitive and specific markers needed for accurate and…
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