Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1030 • 2012 ACR/ARHP Annual Meeting
Frequency and Fluctuation of Susceptibility Artifacts in the Tibio-Femoral Joint Space in Painful Knees On 3T MRI and Association with Meniscal Tears, Radiographic Joint Space Narrowing and Calcifications
Daichi Hayashi¹, Mohamed Jarraya¹, Ali Guermazi², C. Kent Kwoh³, Michael J. Hannon⁴, Carolyn E. Moore⁵, John M. Jakicic⁶, Stephanie M. Green⁷ and Frank Roemer⁸, ¹Department of Radiology, Boston University School of Medicine, Boston, MA, ²Boston University, Boston, MA, ³Rheum & Clinical Immunology, Univ of Pittsburgh, Pittsburgh, PA, ⁴Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁵Department of Nutrition and Food Science, Texas Women's University, Houston, TX, ⁶University of Pittsburgh, PA, ⁷Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁸Klinikum Augsburg, Augsburg, Germany
Background/Purpose: Linear or punctate hypointensities are commonly seen on gradient echo (GRE) sequences in the tibiofemoral joint (TFJ) space of osteoarthritic joints. These magnetic susceptibility…
Abstract Number: 249 • 2012 ACR/ARHP Annual Meeting
Medial Subchondral Bone Marrow Lesions Increase the Odds of Knee Joint Replacement – Data From the Osteoarthritis Initative
Frank Roemer¹, C. Kent Kwoh², David Hunter³, Michael J. Hannon⁴, Robert M. Boudreau⁵, Felix Eckstein⁶, Zhijie Wang⁴, Markus R. John⁷ and Ali Guermazi⁸, ¹Klinikum Augsburg, Augsburg, Germany, ²School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ³Royal North Shore Hospital, St. Leonards, Australia, ⁴Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁵Epidemiology, University of Pittsburgh, Pittsburgh, PA, ⁶Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ⁷Novartis Pharma AG, Basel, Switzerland, ⁸Boston University, Boston, MA
Background/Purpose: Knee joint replacement (KR) is a cost-effective procedure with good long-term outcomes. However, there is no clear consensus on indications for KR. Subchondral bone…
Abstract Number: 1616 • 2012 ACR/ARHP Annual Meeting
Comparison of Conventional and Wholebody Magnetic Resonance Imaging for Assessing Inflammation and Structural Damage in Psoriatic Arthritis and Axial Spondyloarthritis
René Panduro Poggenborg¹, Susanne Juhl Pedersen², Iris Eshed³, Inge Juul Sørensen⁴, Ole Rintek Madsen⁵, J.M. Møller⁶ and Mikkel Østergaard⁷, ¹Department of Rheumatology, Copenhagen University Hospital in Glostrup, Copenhagen, Denmark, ²Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ³Department of Radiology, Sheba Medical Center, Tel Hashomer, Israel, ⁴Department of Rheumatology, Glostrup Hospital, Copenhagen, Denmark, ⁵Department of Rheumatology, Copenhagen University Hospital in Gentofte, Copenhagen, Denmark, ⁶Department of Radiology, Copenhagen University Hospital in Herlev, Copenhagen, Denmark, ⁷Copenhagen University Hospital Glostrup, Glostrup, Denmark
Background/Purpose: Wholebody magnetic resonance imaging (WBMRI) is a new imaging modality where patients are scanned from “head to toe” in one single scan, but with…
Abstract Number: 1034 • 2012 ACR/ARHP Annual Meeting
Changing Osteoarthritis Treatment Assessment Paradigms: Subchondral Bone Is a More Responsive Measure of Progression Than the Current Radiographic Standard
Michael A. Bowes¹, Christopher B. Wolstenholme¹, Devan Hopkinson¹, Graham R. Vincent¹ and Philip G. Conaghan², ¹Imorphics Ltd, Manchester, United Kingdom, ²University of Leeds, Leeds, United Kingdom
Background/Purpose: Radiographic joint space width (JSW) assessment, a surrogate for cartilage assessment, is the standard for structure modification trials of osteoarthritis (OA). However the subchondral…
Abstract Number: 252 • 2012 ACR/ARHP Annual Meeting
Presence of Severe Medial Mensical Pathology Increases the Odds for Knee Replacement: Data From the Osteoarthritis Initiative
Frank Roemer¹, C. Kent Kwoh², David J. Hunter³, Robert M. Boudreau⁴, Michael J. Hannon⁵, Markus R. John⁶, Felix Eckstein⁷, Michel Crema⁸, Zhijie Wang⁵ and Ali Guermazi⁸, ¹Klinikum Augsburg, Augsburg, Germany, ²School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ³Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁴Epidemiology, University of Pittsburgh, Pittsburgh, PA, ⁵Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁶Novartis Pharma AG, Basel, Switzerland, ⁷Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ⁸Boston University, Boston, MA
Background/Purpose: Knee joint replacement (KR) is a cost-effective procedure with good long-term outcome. However, at present there is no clear consensus on indications for KR.…
Abstract Number: 1243 • 2012 ACR/ARHP Annual Meeting
Effect of Tocilizumab Treatment On Regional Left Ventricular Function, As Assessed by Cardiac Magnetic Resonance Imaging, in Rheumatoid Arthritis Patients without Cardiac Symptoms
Hitomi Kobayashi¹, Isamu Yokoe², Hiroshi Sato¹ and Yasuyuki Kobayashi³, ¹Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, ²Nihon University School of Medicine, Tokyo, Japan, ³Radiology, St.Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of congestive heart failure, possibly via shared mechanisms of inflammation. This study was undertaken to…
Abstract Number: 802 • 2012 ACR/ARHP Annual Meeting
Milnacipran Reduces Brain Activity During Pain in Fibromyalgia
Anson E. Kairys¹, Richard E. Harris², Eric Ichesco², Johnson P. Hampson², Steven Harte², Daniel J. Clauw³ and Tobias Schmidt-Wilcke², ¹Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ²Anesthesiology, University of Michigan, Ann Arbor, MI, ³Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI
Background/Purpose: Fibromyalgia (FM) is a chronic pain condition characterized by widespread musculoskeletal pain and a number of concomitant symptoms such as fatigue, sleep disturbance, cognitive…
Abstract Number: 1119 • 2012 ACR/ARHP Annual Meeting
Prediction of MRI-Detected Cartilage Loss Over 30 Months Using Simplified Radiographic and Clinical Stratification: The MOST Study
Frank Roemer¹, David T. Felson², Jingbo Niu³, Yuqing Zhang², Michael C. Nevitt⁴, Michel Crema⁵, Cora E. Lewis⁶, James Torner⁷ and Ali Guermazi⁵, ¹Klinikum Augsburg, Augsburg, Germany, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁴Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁵Boston University, Boston, MA, ⁶Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, ⁷Epidemiology, University of Iowa, Iowa City, Iowa City, IA
Background/Purpose: MRI-detected cartilage loss is the main structural outcome measure in large studies of knee OA. Definition of subjects at high risk for cartilage loss…
Abstract Number: 805 • 2012 ACR/ARHP Annual Meeting
Milnacipran Increases Cortical to Brainstem Connectivity During Pain in Fibromyalgia
Eric Ichesco¹, Tobias Schmidt-Wilcke¹, Anson E. Kairys², Johnson P. Hampson¹, Steven E. Harte¹, Daniel J. Clauw³ and Richard E. Harris¹, ¹Anesthesiology, University of Michigan, Ann Arbor, MI, ²Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ³Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI
Background/Purpose: Fibromyalgia (FM) is a chronic widespread pain disorder characterized by muscle tenderness, fatigue, poor sleep, and mood disturbance. Milnacipran is a dual serotonin-norepinephrine reuptake…
Abstract Number: 1124 • 2012 ACR/ARHP Annual Meeting
Total Knee Replacement As an Osteoarthritis Study Outcome: Predictors Derived From Long-Term Observation Following a Randomized Clinical Trial
Jean-Pierre Raynauld¹, Johanne Martel-Pelletier¹, Marc Dorais², Boulos Haraoui¹, Denis Choquette¹, François Abram³, André Beaulieu⁴, Louis Bessette⁵, Frédéric Morin⁶, Lukas M. Wildi¹ and Jean Pierre Pelletier⁷, ¹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ²StatSciences Inc., Notre-Dame de l’Île Perrot, QC, Canada, ³Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ⁴Faculty of Medicine, Laval University, Quebec, QC, Canada, ⁵Centre Hospitalier Universitaire de Québec, pavillon CHUL, Sainte-Foy, QC, Canada, ⁶Centre de Recherche Musculo-squelettique, Trois-Rivières, QC, Canada, ⁷Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada
Background/Purpose: Using data from a 4-year follow-up of knee OA patients who formerly received treatment with chondroitin sulfate (CS) within a 6-month clinical trial, we…
Abstract Number: 806 • 2012 ACR/ARHP Annual Meeting
Posterior Insula Combined Glutamate and Glutamine Is Associated with Pain in Fibromyalgia: A Replication Study
Eric Ichesco¹, Daniel J. Clauw², Steven E. Harte¹, Anson E. Kairys³, Johnson P. Hampson¹, Tobias Schmidt-Wilcke¹ and Richard E. Harris¹, ¹Anesthesiology, University of Michigan, Ann Arbor, MI, ²Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ³Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI
Background/Purpose: Central pain augmentation resulting from enhanced excitatory and/or decreased inhibitory neurotransmission is a proposed mechanism underlying the pathophysiology of functional pain syndromes such as…
Abstract Number: 1131 • 2012 ACR/ARHP Annual Meeting
Intraarticular Infliximab for Knee Osteoarthritis: High Baseline Levels of Synovial Cellularity and High MRI Cartilage Injury At the Lateral Tibial Plateau Predict Improvement in Total WOMAC Score
Jeremy R. Schue¹, Ossama Tawfik², Rebecca Bolce³, Donald D. Smith¹, Gary Hinson⁴, Jo A. Wick⁵ and Herbert B. Lindsley⁶, ¹Internal Medicine, Kansas University Med Ctr, Kansas City, KS, ²Pathology, Kansas University Med Ctr, Kansas City, KS, ³Crescendo Bioscience Inc., South San Francisco, CA, ⁴Radiology, Kansas University Med Ctr, Kansas City, KS, ⁵Biostatistics, Kansas University Med Ctr, Kansas City, KS, ⁶Medicine, Kansas University Med Ctr, Kansas City, KS
Background/Purpose: Synovial tissue from patients with OA often demonstrates inflammation. We hypothesized that a single intraarticular (IA) injection of an anti-TNF drug would decrease inflammatory…
Abstract Number: 721 • 2012 ACR/ARHP Annual Meeting
Measurement of Pulmonary Arteries by Cardiac Magnetic Resonance Imaging: A Simple and Useful Tool for the Detection of Pulmonary Hypertension in Systemic Sclerosis Patients without Overt Cardiac Microvascular Perfusion Defects or Fibrosis
Sandra Chartrand¹, Lada Miller¹, Martial Koenig², Jean-Richard Goulet¹, Eric Rich¹, Anne S. Chin³, Yves Provost³, Carl Chartrand-Lefebvre³, Pauline Gou¹, Jean-Luc Senécal¹ and Tamara Grodzicky¹, ¹Rheumatology, Hôpital Notre-Dame du CHUM, Montréal, QC, Canada, ²Internal Medicine, Hôpital Notre-Dame du CHUM, Montréal, QC, Canada, ³Radiology, Hôtel-Dieu de Montréal du CHUM, Montréal, QC, Canada
Background/Purpose: Pulmonary hypertension (PH) is a major complication of systemic sclerosis (SSc). We observed that a significant proportion of our SSc patients with PH as…
Abstract Number: 2534 • 2012 ACR/ARHP Annual Meeting
The Intensive Diet and Exercise for Arthritis Trial (IDEA): 18-Month Radiographic and MRI Outcomes
David J. Hunter¹, D. Beavers², Felix Eckstein³, Ali Guermazi⁴, Richard F. Loeser⁵, Barbara J. Nicklas⁶, Shannon Mihalko⁷, Gary D. Miller⁷, Mary Lyles⁸, Paul DeVita⁹, Claudine Legault¹⁰, J. Jeffery Carr¹¹, Jeff D. Williamson⁸ and Stephen P. Messier⁷, ¹Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ²Wake Forest University, Winston Salem, NC, ³Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ⁴Radiology, Boston University, Boston, MA, ⁵Section Of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, ⁶Center on Aging, Wake Forest University School of Medicine, Winston-Salem, NC, ⁷Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, ⁸Center on Aging, Wake Forest University School of Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, ⁹Department of Exercise and Sport Science, East Carolina University, Greenville, NC, ¹⁰Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, ¹¹Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC
Background/Purpose: Dietary induced weight loss is a proven non-pharmacologic intervention for osteoarthritis. Based upon current literature it is unclear if weight loss modifies structural progression.…
Abstract Number: 1103 • 2012 ACR/ARHP Annual Meeting
Cumulative Occupational Physical Load As Risk Factor for Knee Osteoarthritis
Allison M. Ezzat¹, Jolanda Cibere², Mieke Koehoorn³, Eric C. Sayre⁴ and Linda C. Li⁵, ¹School of Rehabilitation Science, University of British Columbia, Vancouver, BC, Canada, ²Division of Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, ³University of British Columbia, Vancouver, BC, Canada, ⁴Arthritis Research Centre of Canada, Vancouver, BC, Canada, ⁵Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Knee osteoarthritis (OA) results from the interaction of multiple risk factors, one of which may be physically demanding occupations. The purpose of this study…

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