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Abstracts tagged "Magnetic resonance imaging (MRI)"

  • Abstract Number: 1941 • 2013 ACR/ARHP Annual Meeting

    Imaging Atherosclerotic Plaque Inflammation In RA: Methodology and Initial Findings In a Single Centre Cohort

    Sarah Skeoch1, Penny Hubbard2, Heather Williams3,4, Dongxiang Xu5, Sun Jie5, Niranjan Balu5, Wei Zhang5, Jacqueline James3, Thomas Hatsukami5, Chun Yuan5, M. Yvonne Alexander6, Paul Hockings7, John Waterton4,8 and Ian N. Bruce9, 1Arthritis Research UK Centre for Epidemiology and NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, 2Centre for Imaging Sciences Biomedical Imaging Institute Oxford Road Manchester, M13 9PT United Kingdom, University of Manchester, Manchester, United Kingdom, 3Department of Nuclear Medicine, Central Manchester University Hospitals Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom, 4Centre for Imaging Sciences Biomedical Imaging Institute, University of Manchester, Manchester, United Kingdom, 5Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, 6Healthcare Science Research Institute, Faculty of Science and Engineering, Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, 7Drug Safety and Metabolism, Astra Zeneca, Mölndal, Sweden, 8R&D Personalised Healthcare & Biomarkers, Astra Zeneca, MACCLESFIELD, United Kingdom, 9Kellgren Centre for Rheumatology, Central Manchester University Hospitals Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom

    Background/Purpose: Chronic inflammation in RA may contribute to an unstable atherosclerotic plaque phenotype. Dynamic contrast enhanced MRI (DCE MRI) can be used to image carotid…
  • Abstract Number: 1586 • 2013 ACR/ARHP Annual Meeting

    Defining Hand Arthritis In Systemic Lupus Erythematosus, From An Ultrasound, Magnetic Resonance Imaging and Antibody Status Perspective

    Elisabeth M.A Ball1, Arthur Grey2, Ai Lyn Tan3, Eiji Fukuba4, Gunter Steiner5, Dennis McGonagle6, Aubrey Bell7 and Madeleine Rooney8, 1Rheumatology, Queens' University/Musgrave Park Hospital, Belfast, United Kingdom, 2Rheumatology, Musgrave Park Hospital, Belfast, United Kingdom, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Department of Radiology, Shimane University, Izuma, Japan, 5Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 6NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, 7Rheumatology Unit, Musgrave Park Hospital, Belfast, United Kingdom, 8Medicine, Queens University Belfast, Belfast, United Kingdom

    Background/Purpose: Musculoskeletal involvement in systemic lupus erythematosus (SLE) is common but poorly characterised with only a few Magnetic Resonance Imaging (MRI) or ultrasound (US) studies…
  • Abstract Number: 1532 • 2013 ACR/ARHP Annual Meeting

    Anti-Tumor Necrosis Fator Therapy Is Associated With Resolution Of Erosion In The Sacroiliac Joints Of Patients With Spondyloarthritis

    Susanne Juhl Pedersen1, Stephanie Wichuk2, Praveena Chiowchanwisawakit3, Robert GW Lambert4 and Walter P. Maksymowych2, 1Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 2Medicine, University of Alberta, Edmonton, AB, Canada, 3Mahidol University, Bangkok, Thailand, 4Radiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Radiography of the sacroiliac joints (SIJ) in spondyloarthritis (SpA) is a valuable diagnostic tool but is unreliable and unresponsive for assessment of treatment effects.…
  • Abstract Number: 1361 • 2013 ACR/ARHP Annual Meeting

    Stringent Therapies Improve Clinical, Radiographic and Magnetic Resonance Imaging Outcome In Early-Stage Rheumatoid Arthritis Patients From Japanese Population: Longitudinal Study From Nagasaki Early Arthritis Cohort

    Mami Tamai1,2, Yoshikazu Nakashima3, Junko Kita4, Ayuko Takatani4, Ayako Nishino3, Takahisa Suzuki3, Yoshiro Horai3, Akitomo Okada5, Shin-ya Kawashiri3,6, Naoki Iwamoto3, Kunihiro Ichinose3, Kazuhiko Arima6, Hideki Nakamura3, Tomoki Origuchi7, Masataka Uetani8, Katsumi Eguchi9 and Atsushi Kawakami3, 1Center for Health & Community Medicine, Nagasaki University, Nagasaki, Japan, 2Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 3Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 4Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 5Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan, 6Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 7Department of Rehabilitation Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 8Department of Radiology and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 9Sasebo City General Hospital, Sasebo, Nagasaki, Japan

    Background/Purpose: Prognosis of the patients with rheumatoid arthritis (RA) nowadays is supposed to become better by treat-to-target (T2T) strategy. Osteitis determined by magnetic resonance imaging…
  • Abstract Number: 1132 • 2013 ACR/ARHP Annual Meeting

    Sensitivity To Change Of Radiographic Fixed-Location and Magnetic Resonance Imaging-Based Cartilage Thickness Measures In The Lateral Compartment Of Knees With Radiographic Osteoarthritis – Data From The Osteoarthritis Initiative

    Wolfgang Wirth1, Jeffrey W. Duryea2, Michael C. Nevitt3, Robert J. Buck4, David Hunter5 and Felix Eckstein1, 1Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 2Radiology, Brigham and Women's Hospital, Boston, MA, 3Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 4StatAnswers Consulting, Minneapolis, MN, 5Royal North Shore Hospital, St. Leonards, Australia

    Background/Purpose: Radiographic joint space width (JSW) is frequently employed to indirectly assess structural progression in the medial femorotibial compartment, but it is unclear whether assessment…
  • Abstract Number: 1116 • 2013 ACR/ARHP Annual Meeting

    A Prospective Evaluation Of The Diagnostic Value Of Conventional Radiography, Ultrasound and MRI In Comparison To Clinical Examination For The Assessment Of Heel and Knee Enthesitis In Patients With Peripheral Spondyloarthritis and Controls

    Xenofon Baraliakos1, Uta Kiltz2, Frank Heldmann3, Heiner Appel4, Friedrich Dybowski5, Manfred Igelmann6, Ludwig H. Kalthoff7, Claudia Klink8, Dietmar MJ Krause9, Ertan Saracbasi3, Elmar Schmitz-Bortz10 and Jürgen Braun3, 1Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Rheumatology and Nephrology Practice, Hamm, Germany, 5Rheumatology Practice, Herne, Germany, 6Private Rheumatology office, Bochum, Germany, 7Private rheumatology office, Herne, Germany, 8Private rheumatology office, Gladbeck, Germany, 9Internistische und rheumatologische Gemeinschaftspraxis, Gladbeck, Germany, 10Rheumatology practice, Hattingen, Germany

    Background/Purpose: Spondyloarthritides (SpA) are characterized by inflammatory and structural changes in the axial skeleton and in peripheral joints and entheses. Imaging has an essential role…
  • Abstract Number: 1127 • 2013 ACR/ARHP Annual Meeting

    Semiquantitative MRI Features Of Knee Osteoarthritis Show Compartment-Specific Relationships With Quantitative Cartilage Thickness Loss: The Multicenter Osteoarthritis Study

    Ali Guermazi1, Felix Eckstein2, Daichi Hayashi3, Frank Roemer4, Wolfgang Wirth2, Tianzhong Yang5, Jingbo Niu6, Leena Sharma7, Michael C. Nevitt8, Cora E. Lewis9, James Torner10 and David T. Felson11, 1Boston University, Boston, MA, 2Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 3Department of Radiology, Boston University School of Medicine, Boston, MA, 4Radiology, Boston University School of Medicine, Boston, MA, 5Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 6Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 7Northwestern University, Chicago, IL, 8Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 9Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, 10Epidemiology, University of Iowa, Iowa City, Iowa City, IA, 11Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: Structural progression of knee OA has been associated with several radiographic and MRI-measured pathological features of OA, including malalignment, meniscal pathology and bone marrow…
  • Abstract Number: 1131 • 2013 ACR/ARHP Annual Meeting

    Peri-Articular Fractal Signature Analysis and Bone Mineral Density Measure Different Aspects Of Bone: Cross-Sectional Data From The Osteoarthritis Initiative

    Jeffrey B. Driban1, Felix Liu2, Alina O'Brien3, Lori Lyn Price4, Grace H. Lo5, Michael C. Nevitt6, Charles Eaton7, Timothy E. McAlindon8 and John A. Lynch9, 1Rheumatology, Tufts Medical Center, Boston, MA, 2University of California at San Francisco, San Francisco, CA, 3Tufts Medical Center, Boston, MA, 4Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 5VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, 6Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 7Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, 8Division of Rheumatology, Tufts Medical Center, Boston, MA, 9Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA

    Background/Purpose: Peri-articular fractal signature analysis (FSA) and bone mineral density (paBMD) are potentially cost-effective prognostic imaging markers for osteoarthritis (OA) progression. While we know that…
  • Abstract Number: 829 • 2013 ACR/ARHP Annual Meeting

    Is The Severity Of Knee Osteoarthritis On MRI Associated With Outcome Of Exercise Therapy?

    Jesper Knoop1, Joost Dekker2, Marike van der Leeden3,4, Martin van der Esch4, J.P. Klein5, David J. Hunter6, Leo D. Roorda4, Martijn P.M. Steultjens7 and Willem F. Lems8, 1Amsterdam Rehabilitation Research Center, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, 2Rehabilitation Medicine, Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 3Rehabilitation Medicine/EMGO, VU University Medical Center, Amsterdam, Netherlands, 4Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, 5Radiology, VU University Medical Center, Amsterdam, Netherlands, 6Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 7Institute for Applied Health Research and School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland, 8Rheumatology, VU University Medical Center, Amsterdam, Netherlands

    Background/Purpose: To evaluate associations between severity of knee osteoarthritis (OA) on MRI and treatment outcome in knee OA patients treated with exercise therapy. Methods: Ninety-five…
  • Abstract Number: 359 • 2013 ACR/ARHP Annual Meeting

    Tocilizumab Treatment Increases Left Ventricular Ejection Fraction and Decreases Left Ventricular Mass Index In Rheumatoid Arthritis Patients Without Cardiac Symptoms : Assessment By Cardiac Magnetic Resonance Imaging At 3.0 Tesla

    Hitomi Kobayashi1,2, Isamu Yokoe3, Hiroshi Sato2, Yasuyuki Kobayashi4, Kihei Yoneyama5, Masaharu Hirano6 and Masami Takei7, 1Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 2Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, 3Nihon University School of Medicine, Tokyo, Japan, 4Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, 5Cardiology, St.Marianna University School of Medicine, Kawasaki, Japan, 6Cardiology, Tokyo Medical Colleage, Tokyo, Japan, 7Division of Hematology and Rheumatology, NIhon University School of Medicine, Tokyo, Japan

    Background/Purpose: Left ventricular (LV) dysfunction in rheumatoid arthritis (RA) may result, at least in part, from inflammation that may be regional and global. Therefore, therapies…
  • Abstract Number: 82 • 2013 ACR/ARHP Annual Meeting

    Anatomical Variation In The Morphology Of The Posterior Cruciate Ligament Synovio-Entheseal Complex and Correlation With Degenerative Change

    Daniel Binks1, Diane Bergin2, Tony Freemont3, Aleksandra Radjenovic1 and Dennis McGonagle4, 1NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, 2Radiology, Galway University Hospitals, Galway, Ireland, 3School of Medicine, University of Manchester, Manchester, United Kingdom, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Ligament attachments are often found to form complex anatomical functional units involving the ligaments themselves as well as associated synovium and bony tuberosities. Furthermore,…
  • Abstract Number: 1243 • 2012 ACR/ARHP Annual Meeting

    Effect of Tocilizumab Treatment On Regional Left Ventricular Function, As Assessed by Cardiac Magnetic Resonance Imaging, in Rheumatoid Arthritis Patients without Cardiac Symptoms

    Hitomi Kobayashi1, Isamu Yokoe2, Hiroshi Sato1 and Yasuyuki Kobayashi3, 1Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, 2Nihon University School of Medicine, Tokyo, Japan, 3Radiology, St.Marianna University School of Medicine, Kawasaki, Japan

    Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of congestive heart failure, possibly via shared mechanisms of inflammation. This study was undertaken to…
  • Abstract Number: 802 • 2012 ACR/ARHP Annual Meeting

    Milnacipran Reduces Brain Activity During Pain in Fibromyalgia

    Anson E. Kairys1, Richard E. Harris2, Eric Ichesco2, Johnson P. Hampson2, Steven Harte2, Daniel J. Clauw3 and Tobias Schmidt-Wilcke2, 1Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, 2Anesthesiology, University of Michigan, Ann Arbor, MI, 3Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI

    Background/Purpose: Fibromyalgia (FM) is a chronic pain condition characterized by widespread musculoskeletal pain and a number of concomitant symptoms such as fatigue, sleep disturbance, cognitive…
  • Abstract Number: 1119 • 2012 ACR/ARHP Annual Meeting

    Prediction of MRI-Detected Cartilage Loss Over 30 Months Using Simplified Radiographic and Clinical Stratification: The MOST Study

    Frank Roemer1, David T. Felson2, Jingbo Niu3, Yuqing Zhang2, Michael C. Nevitt4, Michel Crema5, Cora E. Lewis6, James Torner7 and Ali Guermazi5, 1Klinikum Augsburg, Augsburg, Germany, 2Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 4Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 5Boston University, Boston, MA, 6Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, 7Epidemiology, University of Iowa, Iowa City, Iowa City, IA

    Background/Purpose: MRI-detected cartilage loss is the main structural outcome measure in large studies of knee OA. Definition of subjects at high risk for cartilage loss…
  • Abstract Number: 805 • 2012 ACR/ARHP Annual Meeting

    Milnacipran Increases Cortical to Brainstem Connectivity During Pain in Fibromyalgia

    Eric Ichesco1, Tobias Schmidt-Wilcke1, Anson E. Kairys2, Johnson P. Hampson1, Steven E. Harte1, Daniel J. Clauw3 and Richard E. Harris1, 1Anesthesiology, University of Michigan, Ann Arbor, MI, 2Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, 3Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI

    Background/Purpose: Fibromyalgia (FM) is a chronic widespread pain disorder characterized by muscle tenderness, fatigue, poor sleep, and mood disturbance.  Milnacipran is a dual serotonin-norepinephrine reuptake…
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