ACR Meeting Abstracts

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Abstracts tagged "Magnetic resonance imaging (MRI)"

  • Abstract Number: 854 • 2014 ACR/ARHP Annual Meeting

    Golimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy (SpA): A 48-Week Randomized Controlled Trial

    Chi Chiu Mok1, Angela Li2, Kar Li Chan1 and Ling Yin Ho1, 1Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, 2Radiology, Tuen Mun Hospital, Hong Kong, Hong Kong

    Background/Purpose To compare the efficacy of golimumab(GLM) and pamidronate(PAM) in the treatment of SpA.Methods Inclusion criteria: (1) patients ≥18 years of age; (2) fulfills the…
  • Abstract Number: 151 • 2013 ACR/ARHP Annual Meeting

    The mtDNA Haplogroups Influence The Cartilage Integrity In Osteoarthritis. Data From The Osteoarthritis Initiative (OAI)

    Ignacio Rego-Pérez1, Angel Soto-Hermida2, Mercedes Fernández-Moreno2, Sonia Pértega-Díaz3, Juan Fernández-Tajes2, María Eugenia Vázquez-Mosquera2, Estefanía Cortés-Pereira2, Sara Relaño-Fernández2, Natividad Oreiro-Villar2, Carlos Fernández-López2 and Francisco J. Blanco4,5,6, 1Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, 2INIBIC-Hospital Universitario A Coruña. Rheumatology Division. Genomic Group, A Coruña, Spain, 3Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, 4Osteoarticular and Aging Res. Lab. CIBER-BBN. INIBIC- University of A Coruña, A Coruña, Spain, 5Proteo-Red/ISCIII, Madrid, Spain, 6CIBER-BBN-ISCIII, Madrid, Spain

    Background/Purpose: Magnetic resonance imaging (MRI) is ideally suited for detect structural changes and degradation in cartilage against the limitations of radiographic common methods. Changes in…
  • Abstract Number: 65 • 2013 ACR/ARHP Annual Meeting

    The Frequency Of Bone Marrow Oedema Adjacent To The Cruciate Ligament Peri-Entheseal Vascular Channels In Inflammatory and Degenerative Arthritis

    Daniel Binks1,2, Melissa Matzelle3, Diane Bergin4, Richard J. Hodgson2,5, Ai Lyn Tan1,2, Ellen M. Gravallese6, Dennis McGonagle1,2,7 and Aleksandra Radjenovic1,2, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 2NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, 3Department of Medicine, Division of Rheumatology, University of Massachusetts Medical School, Worcester, MA, 4Radiology, Galway University Hospitals, Galway, Ireland, 5NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 6Department of Medicine, Division of Rheumatology, UMass Memorial Medical Center, Worcester, MA, 7Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: We noted in mouse models of inflammatory arthritis (IA) that an early point of entry of inflammation into the marrow space occurred at sites…
  • Abstract Number: 2839 • 2013 ACR/ARHP Annual Meeting

    Effects Of Treatment On Spinal Fat Lesions As Assessed By MRI With The Fat Spondyloarthritis Spine Score

    Susanne Juhl Pedersen1, Zheng Zhao2, Stephanie Wichuk3, Robert GW Lambert4 and Walter P. Maksymowych3, 1Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 2Department of Rheumatology, University of Alberta and PLA General Hospital, Beijing, PR China, Beijing, AB, China, 3Medicine, University of Alberta, Edmonton, AB, Canada, 4Radiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Fat lesions develop after resolution of inflammation in the spine (1), and have also been shown to predict development of new syndesmophytes (2). Consequently,…
  • Abstract Number: 2805 • 2013 ACR/ARHP Annual Meeting

    Synovial Explant Inflammatory Mediator Production Is Associated With Synovitis While Not With Bone Marrow Edema In Rheumatoid Arthritis: A Cross Sectional Study

    Martin Andersen1, Mikael Boesen2, Karen Ellegaard1, Robin Christensen3, Kalle Söderström4, Søren Torp-Pedersen1, Bente Danneskiold-Samsøe1, Else Marie Bartels5, Nina Vendel6, Niels H. Søe7, Pieter Spee8, Ulrik GW Mørch9, Lars Karlsson4 and Henning Bliddal10, 1Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark, Frederiksberg, Denmark, 2Radiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Department of Radiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark, Frederiskberg, Denmark, 3Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark, Frederiksberg, Denmark, 4Biopharmaceutical Research Unit, Novo Nordisk, Translational Immunology, Biopharmaceutical Research Unit, Måløv, Novo Nordisk, Denmark, Måløv, Denmark, 5Rheumatology, Copenhagen University Hospital,Bispebjerg and Frederiksberg, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark, Frederiksberg, Denmark, 6Department of Anaesthesiology, Intensive Care and Operations, Gentofte University Hospital, Denmark, Hellerup, Denmark, 7Department of Orthopedics, Section of Hand Surgery, Gentofte University Hospital, Department of Orthopedics, Section of Hand Surgery, Gentofte University Hospital, Denmark, Hellerup, Denmark, 8Biopharmaceutical Research Unit Novo Nordisk, Translational Immunology, Biopharmaceutical Research Unit, Måløv, Novo Nordisk, Denmark, Måløv, Denmark, 9Biomarkers, Søborg, Novo Nordisk, Denmark, Biomarkers, Søborg, Novo Nordisk, Denmark, Søborg, Denmark, 10The Parker Institute, Copenhagen, Denmark

    Background/Purpose: Synovitis and bone damage may represent two distinct but overlapping pathological processes in rheumatoid arthritis (RA). Whereas the bulk of synovial cells contribute to…
  • Abstract Number: 2692 • 2013 ACR/ARHP Annual Meeting

    Evidence That Fat Metaplasia Is a Key Intermediary In The Development Of Sacroiliac Joint Ankylosis Following Repair Of Erosions In Patients With Spondyloarthritis

    Walter P. Maksymowych1, Stephanie Wichuk1, Praveena Chiowchanwisawakit2, Robert GW Lambert3 and Susanne Juhl Pedersen4, 1Medicine, University of Alberta, Edmonton, AB, Canada, 2Mahidol University, Bangkok, Thailand, 3Radiology, University of Alberta, Edmonton, AB, Canada, 4Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark

    Background/Purpose: Fat metaplasia is detected as bright signal on T1W MRI and has been shown to develop after resolution of inflammation in spine and sacroiliac…
  • Abstract Number: 1952 • 2013 ACR/ARHP Annual Meeting

    The Value Of An Automated Ultrasound System In The Detection Of Synovitis

    Ruediger Mueller1, Mathias Gruenke2, Joerg Wendler3, Florian Schuch3, Karina Hofmann-Preiss4, Ina Boettger4, Ruediger Jakobs5, Hendrik Schulze-Koops6 and Johannes von Kempis1, 1Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, 2Division of Rheumatoloy, Medizinische Klinik IV, University of Munich, Munich, Germany, 3Schwerpunktpraxis Rheumatologie, Erlangen, Germany, 4Institut für bildgebende Diagnostik und Therapie, Erlangen, Germany, 5Siemens AG, Erlangen, Germany, 6Division of Rheumatology and Clinical Immunology, University of Munich, Munich, Germany

    Background/Purpose: The detection of joint swelling caused by synovitis is important for the diagnosis and assessment of inflammatory arthritis. Ultrasound (US) and MRI have proven…
  • Abstract Number: 1941 • 2013 ACR/ARHP Annual Meeting

    Imaging Atherosclerotic Plaque Inflammation In RA: Methodology and Initial Findings In a Single Centre Cohort

    Sarah Skeoch1, Penny Hubbard2, Heather Williams3,4, Dongxiang Xu5, Sun Jie5, Niranjan Balu5, Wei Zhang5, Jacqueline James3, Thomas Hatsukami5, Chun Yuan5, M. Yvonne Alexander6, Paul Hockings7, John Waterton4,8 and Ian N. Bruce9, 1Arthritis Research UK Centre for Epidemiology and NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, 2Centre for Imaging Sciences Biomedical Imaging Institute Oxford Road Manchester, M13 9PT United Kingdom, University of Manchester, Manchester, United Kingdom, 3Department of Nuclear Medicine, Central Manchester University Hospitals Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom, 4Centre for Imaging Sciences Biomedical Imaging Institute, University of Manchester, Manchester, United Kingdom, 5Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, 6Healthcare Science Research Institute, Faculty of Science and Engineering, Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, 7Drug Safety and Metabolism, Astra Zeneca, Mölndal, Sweden, 8R&D Personalised Healthcare & Biomarkers, Astra Zeneca, MACCLESFIELD, United Kingdom, 9Kellgren Centre for Rheumatology, Central Manchester University Hospitals Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom

    Background/Purpose: Chronic inflammation in RA may contribute to an unstable atherosclerotic plaque phenotype. Dynamic contrast enhanced MRI (DCE MRI) can be used to image carotid…
  • Abstract Number: 1586 • 2013 ACR/ARHP Annual Meeting

    Defining Hand Arthritis In Systemic Lupus Erythematosus, From An Ultrasound, Magnetic Resonance Imaging and Antibody Status Perspective

    Elisabeth M.A Ball1, Arthur Grey2, Ai Lyn Tan3, Eiji Fukuba4, Gunter Steiner5, Dennis McGonagle6, Aubrey Bell7 and Madeleine Rooney8, 1Rheumatology, Queens' University/Musgrave Park Hospital, Belfast, United Kingdom, 2Rheumatology, Musgrave Park Hospital, Belfast, United Kingdom, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Department of Radiology, Shimane University, Izuma, Japan, 5Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 6NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, 7Rheumatology Unit, Musgrave Park Hospital, Belfast, United Kingdom, 8Medicine, Queens University Belfast, Belfast, United Kingdom

    Background/Purpose: Musculoskeletal involvement in systemic lupus erythematosus (SLE) is common but poorly characterised with only a few Magnetic Resonance Imaging (MRI) or ultrasound (US) studies…
  • Abstract Number: 1532 • 2013 ACR/ARHP Annual Meeting

    Anti-Tumor Necrosis Fator Therapy Is Associated With Resolution Of Erosion In The Sacroiliac Joints Of Patients With Spondyloarthritis

    Susanne Juhl Pedersen1, Stephanie Wichuk2, Praveena Chiowchanwisawakit3, Robert GW Lambert4 and Walter P. Maksymowych2, 1Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 2Medicine, University of Alberta, Edmonton, AB, Canada, 3Mahidol University, Bangkok, Thailand, 4Radiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Radiography of the sacroiliac joints (SIJ) in spondyloarthritis (SpA) is a valuable diagnostic tool but is unreliable and unresponsive for assessment of treatment effects.…
  • Abstract Number: 1361 • 2013 ACR/ARHP Annual Meeting

    Stringent Therapies Improve Clinical, Radiographic and Magnetic Resonance Imaging Outcome In Early-Stage Rheumatoid Arthritis Patients From Japanese Population: Longitudinal Study From Nagasaki Early Arthritis Cohort

    Mami Tamai1,2, Yoshikazu Nakashima3, Junko Kita4, Ayuko Takatani4, Ayako Nishino3, Takahisa Suzuki3, Yoshiro Horai3, Akitomo Okada5, Shin-ya Kawashiri3,6, Naoki Iwamoto3, Kunihiro Ichinose3, Kazuhiko Arima6, Hideki Nakamura3, Tomoki Origuchi7, Masataka Uetani8, Katsumi Eguchi9 and Atsushi Kawakami3, 1Center for Health & Community Medicine, Nagasaki University, Nagasaki, Japan, 2Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 3Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 4Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 5Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan, 6Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 7Department of Rehabilitation Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 8Department of Radiology and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 9Sasebo City General Hospital, Sasebo, Nagasaki, Japan

    Background/Purpose: Prognosis of the patients with rheumatoid arthritis (RA) nowadays is supposed to become better by treat-to-target (T2T) strategy. Osteitis determined by magnetic resonance imaging…
  • Abstract Number: 1132 • 2013 ACR/ARHP Annual Meeting

    Sensitivity To Change Of Radiographic Fixed-Location and Magnetic Resonance Imaging-Based Cartilage Thickness Measures In The Lateral Compartment Of Knees With Radiographic Osteoarthritis – Data From The Osteoarthritis Initiative

    Wolfgang Wirth1, Jeffrey W. Duryea2, Michael C. Nevitt3, Robert J. Buck4, David Hunter5 and Felix Eckstein1, 1Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 2Radiology, Brigham and Women's Hospital, Boston, MA, 3Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 4StatAnswers Consulting, Minneapolis, MN, 5Royal North Shore Hospital, St. Leonards, Australia

    Background/Purpose: Radiographic joint space width (JSW) is frequently employed to indirectly assess structural progression in the medial femorotibial compartment, but it is unclear whether assessment…
  • Abstract Number: 1116 • 2013 ACR/ARHP Annual Meeting

    A Prospective Evaluation Of The Diagnostic Value Of Conventional Radiography, Ultrasound and MRI In Comparison To Clinical Examination For The Assessment Of Heel and Knee Enthesitis In Patients With Peripheral Spondyloarthritis and Controls

    Xenofon Baraliakos1, Uta Kiltz2, Frank Heldmann3, Heiner Appel4, Friedrich Dybowski5, Manfred Igelmann6, Ludwig H. Kalthoff7, Claudia Klink8, Dietmar MJ Krause9, Ertan Saracbasi3, Elmar Schmitz-Bortz10 and Jürgen Braun3, 1Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Rheumatology and Nephrology Practice, Hamm, Germany, 5Rheumatology Practice, Herne, Germany, 6Private Rheumatology office, Bochum, Germany, 7Private rheumatology office, Herne, Germany, 8Private rheumatology office, Gladbeck, Germany, 9Internistische und rheumatologische Gemeinschaftspraxis, Gladbeck, Germany, 10Rheumatology practice, Hattingen, Germany

    Background/Purpose: Spondyloarthritides (SpA) are characterized by inflammatory and structural changes in the axial skeleton and in peripheral joints and entheses. Imaging has an essential role…
  • Abstract Number: 1127 • 2013 ACR/ARHP Annual Meeting

    Semiquantitative MRI Features Of Knee Osteoarthritis Show Compartment-Specific Relationships With Quantitative Cartilage Thickness Loss: The Multicenter Osteoarthritis Study

    Ali Guermazi1, Felix Eckstein2, Daichi Hayashi3, Frank Roemer4, Wolfgang Wirth2, Tianzhong Yang5, Jingbo Niu6, Leena Sharma7, Michael C. Nevitt8, Cora E. Lewis9, James Torner10 and David T. Felson11, 1Boston University, Boston, MA, 2Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 3Department of Radiology, Boston University School of Medicine, Boston, MA, 4Radiology, Boston University School of Medicine, Boston, MA, 5Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 6Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 7Northwestern University, Chicago, IL, 8Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 9Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, 10Epidemiology, University of Iowa, Iowa City, Iowa City, IA, 11Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: Structural progression of knee OA has been associated with several radiographic and MRI-measured pathological features of OA, including malalignment, meniscal pathology and bone marrow…
  • Abstract Number: 1131 • 2013 ACR/ARHP Annual Meeting

    Peri-Articular Fractal Signature Analysis and Bone Mineral Density Measure Different Aspects Of Bone: Cross-Sectional Data From The Osteoarthritis Initiative

    Jeffrey B. Driban1, Felix Liu2, Alina O'Brien3, Lori Lyn Price4, Grace H. Lo5, Michael C. Nevitt6, Charles Eaton7, Timothy E. McAlindon8 and John A. Lynch9, 1Rheumatology, Tufts Medical Center, Boston, MA, 2University of California at San Francisco, San Francisco, CA, 3Tufts Medical Center, Boston, MA, 4Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 5VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, 6Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 7Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, 8Division of Rheumatology, Tufts Medical Center, Boston, MA, 9Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA

    Background/Purpose: Peri-articular fractal signature analysis (FSA) and bone mineral density (paBMD) are potentially cost-effective prognostic imaging markers for osteoarthritis (OA) progression. While we know that…
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