Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 3084 • 2015 ACR/ARHP Annual Meeting
Progression of Lupus Pathology Is Correlative with Cardiac Magnetic Resonance Imaging Abnormalities, Diminished Function, and Inflammatory Histopathology in an Animal Model
Nicholas Young¹, Jeffrey Hampton¹, Saba Aqel¹, Jessica Pyles², Anna Bratasz², Anuradha Kalyanasundaram³, Wael N. Jarjour⁴ and Stacy P. Ardoin⁵, ¹Immunology and Rheumatology, The Ohio State University Medical Center, Columbus, OH, ²Small Animal Imaging Core, The Ohio State University Medical Center, Columbus, OH, ³Physiology and Cell Biology, The Ohio State University Medical Center, Columbus, OH, ⁴Department of Internal Medicine, Division of Immunology and Rheumatology, The Ohio State University Medical Center, Columbus, OH, ⁵Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease causing inflammation throughout the body and cardiovascular involvement is a significant contributor to morbidity and mortality…
Abstract Number: 297 • 2015 ACR/ARHP Annual Meeting
How Useful Is Magnetic Resonance Imaging (MRI) in Monitoring Patients with Myositis?
Nicolo Pipitone¹, Antonella Notarnicola², Arnaldo Scardapane³, Gabriele Levrini⁴, Lucia Spaggiari⁵, Florenzo Iannone⁶, Giovanni Lapadula⁶, Giulio Zuccoli⁷ and Carlo Salvarani⁸, ¹Unità di Reumatologia, Reggio Emilia, Arcispedale Santa Maria Nuova, Bari, Italy, ²Karolinska Hospital, Rheumatology Unit, Stockholm, Sweden, ³Radiology, University of Bari, Bari, Italy, ⁴Arcispedale S Maria Nuova, Reggio Emilia, Italy, ⁵Radiology, Arcispedale S Maria Nuova, Reggio Emilia, Italy, ⁶Bari University, Rheumatology, Bari, Italy, ⁷Children's Hospital of Pittsburgh, Pittsburgh, PA, ⁸Rheumatology, Arcispedale S.Maria Nuova, Reggio Emilia, Italy
Background/Purpose: MRI is commonly used to assess muscle inflammation in myositis. Muscle edema on fat-suppressed sequences is thought to reflect active inflammation. However, it is…
Abstract Number: 3125 • 2015 ACR/ARHP Annual Meeting
White Matter Magnetization Transfer Ratio Histogram Peak Height Helps Identifying Inflammatory Neuropsychiatric Systemic Lupus Erythematosus
César Magro Checa¹, Ece Ercan², Bart J Emmer³, Ron Wolterbeek⁴, Itamar Ronen², Mark A. Van Buchem², T. W. J. Huizinga⁵ and Gerda M. Steup-Beekman⁵, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Radiology, Erasmus Medical Center, Rotterdam, Netherlands, ⁴Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Magnetization transfer ratio (MTR) can be used to detect microstructural cerebral changes in normal-appearing brain tissue of neuropsychiatric systemic lupus erythematosus (NPSLE) patients. Our…
Abstract Number: 313 • 2015 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging Outcomes Using an Intra-Articular Injection (SM04690) in the Treatment of Osteoarthritis of the Knee: Interim, Exploratory Analysis of Results from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study
Yusuf Yazici¹, Sharmila Majumdar², Timothy E. McAlindon³, Roy Fleischmann⁴, Allan Gibofsky⁵, Marc C. Hochberg⁶, Christopher J. Swearingen¹, Anita DiFrancesco¹, Jeyanesh R. S. Tambiah¹, John Hood¹ and Nancy E. Lane⁷, ¹Samumed, San Diego, CA, ²Radiology, UCSF School of Medicine, San Francisco, CA, ³Rheumatology, Tufts Medical Center, Boston, MA, ⁴University of Texas Southwestern Medical Center, Dallas, TX, ⁵Weill Cornell Medical College and Hospital for Special Surgery, New York, NY, ⁶Department of Medicine, University of Maryland, Baltimore, MD, ⁷Center for Musculoskeletal Health, Univ of California at Davis, Sacramento, CA
Background/Purpose: Knee osteoarthritis (OA) is characterized by the destruction of articular cartilage, subchrondral bone alterations and varying degrees of synovitis. Current OA treatments are limited…
Abstract Number: 330 • 2015 ACR/ARHP Annual Meeting
Calf Muscle Adiposity Is Associated with Impaired Physical Performance in Knee OA
Michael Davison¹, Monica R. Maly², Jonathan D. Adachi³ and Karen A. Beattie⁴, ¹School of Medicine, McMaster University, Hamilton, ON, Canada, ²School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada, ³Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ⁴Medicine, McMaster University, Hamilton, ON, Canada
Background/Purpose: Knee osteoarthritis (OA) is a degenerative disease associated with significant muscle weakness and disability. Ectopic fat in the thigh, including intramuscular fat (intraMF; fat…
Abstract Number: 927 • 2015 ACR/ARHP Annual Meeting
Ultrasound Assessment of Heel Entheses in Spondyloarthritis Patients: A Comparative Study with Radiography and Magnetic Resonance Imaging
Rodrigo Aguila Maldonado¹, Santiago Ruta², Claudia Elizabeth Pena¹, Maria Laura Valuntas³, Gisela Pendón⁴, Dora Pereira⁴ and Mercedes Argentina García⁵, ¹Rheumatology Unit, HIGA San Martín La Plata, La Plata, Argentina, ²Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Servicio de Tomografía Computada y Resonancia Magnética, Sanatorio IPENSA, La Plata, Argentina, ⁴Hospital Ricardo Gutierrez, La Plata, La Plata, Argentina, ⁵Rheumatology Unit, HIGA San Martín, La Plata, Argentina
Background/Purpose: enthesitis is one of the main hallmarks of Spondyloarthritis (SpA), being heel entheses frequently involved. Different imaging modalities, such as conventional radiography (CR), ultrasound…
Abstract Number: 1300 • 2015 ACR/ARHP Annual Meeting
Comparison Between Semiquantitative and Quantitative Methods for the Assessment of Knee Synovitis Using Non-Enhanced and Gadolinium-Enhanced MRI
Michel D. Crema¹, Frank Roemer², Ling Li³, Laura B. Rosen⁴, Amanda Dudley⁵, Robert Alexander⁶ and Ali Guermazi⁷, ¹Department of Radiology, Boston University School of Medicine, Boston, MA, ²Radiology, Boston University School of Medicine, Boston, MA, ³Dana-Farber Cancer Institute, Boston, MA, ⁴AstraZeneca Neuroscience Innovative Medicines, Cambridge, MA, ⁵AstraZeneca Neuroscience Innovative Medicines, Cambridge, United Kingdom, ⁶Pfizer Neuroscience, Cambridge, MA, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: There is evidence that the presence of synovitis in knee osteoarthritis (OA) is clinically relevant since it is associated with pain and structural…
Abstract Number: 1301 • 2015 ACR/ARHP Annual Meeting
Pain Central Sensitization Assessed By Functional Magnetic Resonance Imaging in Patients with Knee Osteoarthritis
Jordi Monfort¹, Jesus Pujol², Marina Lopez³, Jone Llorente³, Gerard Martinez², Didac Macià², Francisco Montañés³, Miguel Angel Campillo³, Pedro Benito Ruiz⁴ and Joan Deus², ¹Rheumatology Department, Hospital del Mar, Barcelona, Spain, ²Magnetic Ressonance Imaging Unit, Barcelona, Spain, ³Rheumatology Department, Barcelona, Spain, ⁴Rheumatology Service, Hospital del Mar, Barcelona, Spain
Background/Purpose: An important aspect in chronic pain is central sensitization (CS) which involves increased responsiveness of the central neurons and it is clinically expressed like…
Abstract Number: 2986 • 2014 ACR/ARHP Annual Meeting
Fat Metaplasia on MRI of the Sacroiliac Joints Is a Lead Indicator of Radiographic Progression in the Spine of Patients with Ankylosing Spondylitis
Walter P. Maksymowych¹, S Wichuk², P Chiowchanwisawakit³, RG Lambert⁴ and Sj Pedersen⁵, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Department of Medicine, University of Alberta, Edmonton, AB, Canada, ³Mahidol University, Bangkok, Thailand, ⁴Radiology, University of Alberta, Edmonton, AB, Canada, ⁵Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark
Fat Metaplasia on MRI of the Sacroiliac joints is a Lead Indicator of Radiographic Progression in the Spine of Patients with Ankylosing SpondylitisMaksymowych WP, Wichuk…
Abstract Number: 2993 • 2014 ACR/ARHP Annual Meeting
MRI in Neuropsychiatric Lupus: Correlations with the 1999 ACR Case Definitions
Minyoung Her¹, Dongyook Kim², Na young Park², Seong-Kyu Kim³, Lee Sung Won⁴ and Lee sang Yeob⁵, ¹Pusan Paik Hospital, Inje Univ, Inje University, Pusan Paik Hospital, Busan, South Korea, Busan, South Korea, ²Inje University, Pusan Paik Hospital, Busan, South Korea, Busan, South Korea, ³Devision of Rheumatology, Department of Internal Medicine, Arthritis & Autoimmunity Research Center, Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁴Dong-A university,Busan, South Korea, Pusan, South Korea, ⁵Dong -A university, Dong-A university,Busan, South Korea, Pusan, South Korea
Background/Purpose: Neurological manifestations in SLE are diverse. Because of its varied manifestations and low prevalence, the ACR has developed nomenclature and case definitions for neuropsychiatric…
Abstract Number: 2661 • 2014 ACR/ARHP Annual Meeting
Serum Neuronal Biomarkers and Brain Atrophy in Childhood-Onset Systemic Lupus Erythematosus
Aline T. Lapa¹, Mariana Postal¹, Nailu A. Sinicato¹, Renata Barbosa², Fernando Cendes³, Roberto Marini⁴ and Simone Appenzeller⁵, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Medicine, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Germany, ³Neurology, State University of Campinas, Campinas, Brazil, ⁴Departament of Pediatrics, State University of Campinas, Campinas, Brazil, ⁵Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose We aimedto investigate the association of serum biomarkers and regional and diffuse brain atrophy in cSLE. Methods We included consecutive cSLE patients (disease-onset before…
Abstract Number: 2660 • 2014 ACR/ARHP Annual Meeting
Metabolic Syndrome Features Can Influenciate Cognitive Functions and Brain Lesions in Childhood-Onset Systemic Lupus Erythematosus
Nailu A. Sinicato¹, Aline T. Lapa¹, Mariana Postal¹, Bruna Bellini¹, Paula T Fernandes², Roberto Marini³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Faculty of Physical Education, State University of Campinas, Campinas, Brazil, ³Departament of Pediatrics, State University of Campinas, Campinas, Brazil, ⁴Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: The underlying factor for an association between the metabolic syndrome (MetS) and cognitive decline might be a subclinical inflammation. Inflammatory mechanisms are hypothesized to…
Abstract Number: 2613 • 2014 ACR/ARHP Annual Meeting
Positive Spine MRI for Inflammation Predicts Radiographic Progression in Patients with Ankylosing Spondylitis
Walter P. Maksymowych¹, S Wichuk², Z Zhao³, P Chiowchanwisawakit⁴, RG Lambert⁵ and Sj Pedersen⁶, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Department of Medicine, University of Alberta, Edmonton, AB, Canada, ³PLA General Hospital, Beijing, China, ⁴Mahidol University, Bangkok, Thailand, ⁵Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark
Background/Purpose: Inflammation at vertebral corners on MRI has been shown to predict development of syndesmophytes in patients with AS. However, it is unclear at a…
Abstract Number: 1183 • 2014 ACR/ARHP Annual Meeting
Validation of the Omeract Psoriatic Arthritis Magnetic Resonance Imaging Score for the Hand and Foot in a Randomized Placebo-Controlled Trial
Daniel Malm¹, P. Bird², Frédérique Gandjbakhch³, Philip J. Mease⁴, Pernille Bøyesen⁵, Mikkel Østergaard⁶, Charles G. Peterfy⁷ and Philip G. Conaghan⁸, ¹Center for Rheumatology and Spinal Diseases, Copenhagen University Hospital at Glostrup, Glostrup, Denmark, ²Combined Rheumatology Practice, Sydney, Australia, ³Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, Paris, France, ⁴Swedish Medical Center and University of Washington, Seattle, WA, ⁵Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Glostrup, Denmark, ⁷Spire Sciences LLC, Boca Raton, FL, ⁸Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, United Kingdom
Background/Purpose The joint involvement in psoriatic arthritis (PsA) is heterogeneous, and inflammation is seen in both axial and peripheral joints, including the small joints of…
Abstract Number: 1174 • 2014 ACR/ARHP Annual Meeting
Evaluating MRI-Detected Tenosynovitis of the Hand and Wrist in Early Arthritis
W.P. Nieuwenhuis¹, A. Krabben¹, W. Stomp², T. W. J. Huizinga¹, D. M. van der Heijde¹, J.L Bloem², M. Reijnierse³ and A.H.M. van der Helm-van Mil¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands
Background/Purpose Magnetic resonance imaging (MRI) is a sensitive method to detect local inflammation in rheumatoid arthritis (RA), visualizing synovitis, bone marrow edema and tenosynovitis. The…

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