Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1187 • 2019 ACR/ARP Annual Meeting
Delayed Gadolinium-enhanced MR Imaging of Cartilage – A Pilot Study to Measure the Effect of Adalimumab Plus MTX versus Placebo Plus MTX on Cartilage in Early RA Patients (CAR-ERA-Study)
Philipp Sewerin¹, Miriam Frenken ², Ralph Brinks ³, Christoph Schleich ², Daniel Benjamin Abrar ², Stefan Vordenbaeumen ⁴, Ruben Sengewein ⁵, Jutta Richter ⁶, Matthias Schneider ⁷ and Benedikt Ostendorf ⁴, ¹Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, ²Institute for Diagnostic and Interventional Radiology, UKD, Heinrich Heine University, Duesseldorf, Germany, ³Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, ⁴Policlinic and Hiller Research Unit of Rheumatology, UKD, Heinrich Heine University, Duesseldorf, Germany, ⁵Policlinic and Hiller Research Unit of Rheumatology,, Duesseldorf, Germany, ⁶Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, Nordrhein-Westfalen, Germany, ⁷Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany
Background/Purpose: The purpose of this longitudinal study is to compare the effect of Adalimumab plus Methotrexate (MTX) versus MTX monotherapy on glycosaminoglycan content (GAG) in…
Abstract Number: 280 • 2019 ACR/ARP Annual Meeting
Ultrasound versus Conventional Treat-To-Target Strategies in Early Rheumatoid Arthritis: Magnetic Resonance Imaging Outcome Data from a 2-year Randomized Controlled Strategy Trial
Ulf Sundin¹, Anna-Birgitte Aga ², Øivind Skare ³, Lena Nordberg ³, Till Uhlig ⁴, Hilde Hammer ³, Désirée van der Heijde ⁵, Tore Kvien ⁴, Siri Lillegraven ⁶ and Espen Haavardsholm ⁴, ¹Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Norway. University of Oslo, Oslo, Norway, Oslo, Oslo, Norway, ²Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Oslo, Norway, ³Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Norway, ⁴Diakonhjemmet Hospital, Dept. of Rheumatology / University of Oslo, Faculty of Medicine, Oslo, Norway, ⁵Leiden University Medical Center, Leiden, Netherlands, ⁶Diakonhjemmet Hospital, Dept. of Rheumatology, Oslo, Norway
Background/Purpose: It has been debated whether treatment outcomes in early RA would be improved by targeting imaging remission, assessed by ultrasound or MRI, in addition…
Abstract Number: 1299 • 2019 ACR/ARP Annual Meeting
Clinical Significance of Magnetic Resonance Imaging Derived Femur Bone Shape in Young Adults
Minh-Tu Vo ¹, Michael Bowes ², Alison Venn ³, Flavia Cicuttini ⁴, Lyn March ⁵, Terence Dwyer ⁶, Tao Meng ³, Marita Cross ⁵, Graeme Jones ⁷, Saliu Balogun ¹, Changhai Ding ⁷ and Benny Antony⁷, ¹University of Tasmania, Hobart, Tasmania, Australia, ²Imorphics, Manchester, England, United Kingdom, ³University of Tasmania, Hobart, Australia, ⁴Monash University, Melbourne, Australia, ⁵University of Sydney, Sydney, Australia, ⁶University of Oxford, Oxford, United Kingdom, ⁷Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: The femur bone shape derived from magnetic resonance imaging (MRI) of the knee is associated with the incidence and progression of knee osteoarthritis (OA),…
Abstract Number: 297 • 2019 ACR/ARP Annual Meeting
Ultrasound and Magnetic Resonance Imaging Evaluation of the Fingers’ Joints of Psoriatic Arthritis Patients – Interim Analysis
Ari Polachek¹, Victoria Furer ², Mirna Zureik ², Sharon Nevo ², Liran Mendel ², David Levartovsky ³, Jonathan Wollman ⁴, Valerie Aloush ⁵, Mark Berman ⁶, Ilana Kaufman ⁶, Yael Lahat ², Hagit Sarbagil-Maman ⁷, Sara Borok ⁶, Adi Broyde ⁶, Lihi Eder ⁸, Daphna Paran ¹, Iris Eshed ⁹ and Ori Elkayam ¹⁰, ¹Tel-Aviv Sourasky medical center, Tel Aviv, Israel, ²Sourasky Medical Center, Tel-Aviv, Israel, ³Sourasky medical center, Tel Aviv, Israel, ⁴Sourasky Medical Center, Herzelia, Israel, ⁵Tel Aviv Sourasky medical center, Tel Aviv, ⁶Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁷Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, ⁸Women’s College Hospital and the Department of Medicine, University of Toronto, Toronto, Canada, ⁹Sheba Medical Center, Tel-Aviv, Israel, ¹⁰Rheumatology Department, Tel Aviv Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Israel., Tel Aviv, Israel
Background/Purpose: Psoriatic arthritis (PsA) is an inflammatory disease affecting up to 30% of psoriasis patients. PsA can involve both the peripheral and axial skeleton and…
Abstract Number: 1321 • 2019 ACR/ARP Annual Meeting
What Is the Relationship Between the 3 Knee Bones in Osteoarthritis? Baseline and Longitudinal Associations Using a Latent Growth Modelling Approach on 37,583 MR Images from the Osteoarthritis Initiative
Bright Dube¹, Michael Bowes ², Elizabeth Hensor ¹, Sarah Kingsbury ³ and Philip G Conaghan ⁴, ¹University of Leeds, LEEDS, England, United Kingdom, ²Imorphics, Manchester, England, United Kingdom, ³University of Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom
Background/Purpose: 3D femur bone shape measured by statistical shape modelling (SSM) provides a responsive biomarker of knee OA. However it is unclear how the 3…
Abstract Number: 301 • 2019 ACR/ARP Annual Meeting
PANLAR Ultrasound Study Group Recommendations for the Use of Imaging in the Management of Patients with Gout
Marwin Gutierrez ¹, Carlos Pineda ¹, Janitzia Vazquez-Mellado ², Mario Moreno Alvarez ³, Javier Rosa ⁴, Anthony Reginato⁵, Mario Chavez ⁶, Magaly Alva Linares ⁷, Marcelo Audisio ⁸, José Alexandre Mendonca ⁹, Tomas Cazenave ¹⁰, Oscar Sedano ¹¹, Lucio Ventura Ríos ¹², Eugenio de Miguel ¹³, Gurjit Kaeley ¹⁴, Eduardo Scheines ¹⁰, Fritz Hofmann ¹⁵, Gabriel Aguilar ¹⁶, Christian Waimann ¹⁷, Florencia Marengo ¹⁷ and Santiago Ruta ¹⁸, ¹Division of Musculoskeletal and Rheumatic Diseases, Instituto Nacional de Rehabilitación “Luis Guillermo Ibarra Ibarra”, Mexico, Mexico, Mexico, ²Rheumatology Department, Hospital General de Mexico, Mexico, Mexico, ³Rheumatology Department, Hospital General Luis Vernaza, Guayaquil, Ecuador., Guayaquil, Ecuador, ⁴Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina, Buenos Aires, Argentina, ⁵Division of Rheumatology, Providence VAMC, Associate Professor in Medicine, The Warren Alpert School of Medicine, Providence, ⁶Universidad Autónoma de Aguascalientes Aguascalientes, México., Aguascalientes, Mexico, ⁷Rheumatology Department, Hospital Edgardo Rebagliati Martins, Lima, Peru., Lima, Peru, ⁸Rheumatology Department, Hospital Nacional de Clínicas, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Argentina., Cordoba, Argentina, ⁹Rheumatology Department, Pontifical Catholic University of Campinas, Brazil, Campinas, Brazil, ¹⁰Rheumatology Section, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina, ¹¹Reumatology Section, Hospital Marino Molina Scippa, Lima, Perú, Lima, Peru, ¹²Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra Ibarra", México, Mexico, Mexico, ¹³Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ¹⁴Division of Rheumatology, University of Florida College of Medicine, Jacksonville, FL., Florida, ¹⁵Diagnostik Group, Puerto Vallarta, México., Puerto Vallarta, Mexico, ¹⁶Centro Diagnóstico Rossi, Buenos Aires, Argentina, Buenos Aires, Argentina, ¹⁷Rheumatology Unit, Hospital Dr. Héctor Cura, Olavarría, Argentina., Olavarria, Argentina, ¹⁸Rheumatology Department, Hospital San Martín de La Plata and Rheumatology Unit, Hospital Italiano de La Plata, Argentina., La Plata, Argentina
Background/Purpose: Gout is a metabolic disease caused by deposition of monosodium urate (MSU) monohydrate crystals in different tissues. Imaging may be useful to evaluate the…
Abstract Number: 1506 • 2019 ACR/ARP Annual Meeting
Long‑Term Certolizumab Pegol Treatment of Axial Spondyloarthritis Is Associated with Rapid and Sustained Reduction of Active Inflammation and Minimal Structural Changes in the Spine: 4‑Year MRI Results
Xenofon Baraliakos¹, Sebastian Kruse ², Simone Auteri ³, Natasha de Peyrecave ⁴, Tommi Nurminen ⁵, Thomas Kumke ⁵, Bengt Hoepken ⁶ and Jürgen Braun ², ¹Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, ²Rheumazentrum Ruhrgebiet/Ruhr University, Herne, Germany, ³UCB Pharma, Brussels, Belgium, ⁴UCB Pharma, Slough, United Kingdom, ⁵UCB Pharma, Monheim, Germany, ⁶UCB Pharma, Monheim am Rhein, Germany
Background/Purpose: Inflammation of the spine is believed to trigger a repair mechanism that results in syndesmophyte formation in axial spondyloarthritis (axSpA) patients (pts).1 Bone marrow…
Abstract Number: 505 • 2019 ACR/ARP Annual Meeting
Low-grade Total Rheumatoid Arthritis MRI Scoring System Can Predict Successful Half-dose Reduction of MTX in Patients with RA in Clinical Remission
Takeshi Suzuki¹, Marina Uchida ², Shoshi Shinagawa ², Machiko Mizushima ³, Takayasu Ando ³, Yutaka Gotou ³, Tomohiko Shibata ² and Kimito Kawahata ⁴, ¹Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ²Division of Rheumatology, Department of Internal Medicine, St. Marianna University School of Medicine, Yokohama City Seibu Hospital, Yokohama, Kanagawa, Japan, ³Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan, ⁴Rheumatology and Allergology, St. Marianna University School of Medicine, Tokyo, Japan
Background/Purpose: It has been recommended that tapering csDMARDs should be considered if a patient is in persistent remission. However, methods for tapering csDMARDs, including MTX,…
Abstract Number: 1521 • 2019 ACR/ARP Annual Meeting
Ixekizumab Is Effective in the Treatment of Radiographic Axial Spondyloarthritis Regardless of the Level of C-Reactive Protein or Magnetic Resonance Imaging Scores
Walter P. Maksymowych¹, Gaia Gallo ², Rebecca Bolce ³, Fangyi Zhao ², Vladimir Geneus ³, Mikkel Østergaard ⁴, Kurisu Tada ⁵, Atul Deodhar ⁶ and Lianne Gensler ⁷, ¹University of Alberta/CARE ARTHRITIS, Edmonton, AB, Canada, ²Eli Lilly and Company, Indianapolis, IN, ³Eli Lilly and Company, Indianapolis, ⁴Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, ⁵Juntendo University School of Medicine, Tokyo, Japan, ⁶Oregon Health & Science University, Portland, OR, ⁷University San Francisco California, San Francisco, CA
Background/Purpose: IL-17 plays an important role in the pathogenesis of radiographic axial spondyloarthritis (r-axSpA). Elevated CRP levels in serum predict response to TNF inhibitors (TNFi).1-4…
Abstract Number: 591 • 2019 ACR/ARP Annual Meeting
Longitudinal Assessment of MRI of the Sacroiliac Joints in the ASAS Classification Cohort: Evolution of Diagnostic Features and Predictive Utility for Axial Spondyloarthritis
Walter P. Maksymowych¹, Xenofon Baraliakos ², Manouk de Hooge ³, Iris Eshed ⁴, Susanne Juhl Pedersen ⁵, Ulrich Weber ⁶, Joachim Sieper ⁷, Stephanie Wichuk ⁸, Denis Poddubnyy ⁹, Martin Rudwaleit ¹⁰, Désirée van der Heijde ¹¹, Robert B.M. Landewé ¹², Joel Paschke ¹³, Robert Lambert ⁸ and Mikkel Østergaard ¹⁴, ¹University of Alberta/CARE ARTHRITIS, Edmonton, AB, Canada, ²Rheumatology Department, Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ³Ghent University Hospital, Ghent, Belgium, ⁴Sheba Medical Center, Tel Aviv, Israel, ⁵Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, ⁶Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, Sonderborg, Denmark, ⁷Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ⁸University of Alberta, Edmonton, Canada, ⁹Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ¹⁰Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ¹¹Leiden University Medical Center, Leiden, Netherlands, ¹²Amsterdam University Medical Center, Amsterdam, Netherlands, ¹³CARE Arthritis, Edmonton, Canada, ¹⁴Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Follow up of the ASAS Classification Cohort (CC) indicated a high positive predictive value for the ASAS classification criteria derived from baseline patient and…
Abstract Number: 1738 • 2019 ACR/ARP Annual Meeting
Tracking Whole-Brain Volumetric Trends in Childhood-onset Systemic Lupus Erythematosus Patients in the Clinical Setting by Magnetic Resonance Imaging
Hermine Brunner¹, Arjun Mathur ², William O'Brien ³ and Mark DiFrancesco ³, ¹Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ²Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: The course of childhood-onset Systemic Lupus Erythematosus (cSLE) commonly includes neurocognitive dysfunction, a manifestation with poor prognosis. It has been challenging to diagnose and…
Abstract Number: L05 • 2018 ACR/ARHP Annual Meeting
Treatment-Naïve, Early Rheumatoid Arthritis Patients Demonstrate Reversible Abnormalities of Vascular Function on Cardiac MRI with RA Therapy with Preliminary Suggestion of Greater Improvement with Anti-TNF Compared to MTX/Conventional Therapy – a First, RCT Derived Longitudinal Study
Maya H. Buch¹, Bara Erhayiem², Graham Fent², Paul Baxter³, Elizabeth M.A. Hensor⁴, Adam McDiarmid², Peter Swoboda⁵, Ananth Kidambi², David Ripley², Pankaj Garg², Sarah Horton⁴, Raluca Bianca Dumitru⁴, Kamran Naraghi⁴, John Greenwood⁶, Paul Emery⁷, Sue Pavitt⁸ and Sven Plein², ¹Leeds Institute of Rheumatic & Musculosekeltal Medicine, University of Leeds & NIHR Biomedical Research Centre, Leeds, United Kingdom, ²Multidisciplinary Cardiovascular Research Centre, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ³Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Cardiovascular And Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ⁶Leeds Institute of Cardiovascular And Metabolic Medicinee, University of Leeds, Leeds, United Kingdom, ⁷University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ⁸Leeds School of Dentistry, University of Leeds, Leeds, United Kingdom
Background/Purpose: We previously reported abnormal cardiac MRI (CMR)-determined aortic stiffness in patients with early, treatment-naive RA1,2. We now report on whether this vascular stiffness is…
Abstract Number: 319 • 2018 ACR/ARHP Annual Meeting
Patterns of Muscle Oedema, Atrophy and Fatty Replacement in the Idiopathic Inflammatory Myopathies: A Single-Centre Retrospective Review of Magnetic Resonance Imaging Data
Jessica Day^1,2, Nicholas Bajic³, Sheridan Gentili⁴, Sandy Patel⁵ and Vidya Limaye⁶, ¹Rheumatology, Royal Adelaide Hospital, Adelaide, Australia, ²Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia, ³Dr Jones and Partners St Andrew's and Calvary Wakefield Hospitals, Adeliad, Australia, ⁴University of South Australia, Adelaide, Australia, ⁵Radiology, Royal Adelaide Hospital, Adelaide, Australia, ⁶Rheumatology, The Royal Adelaide Hospital, Adelaide, Australia
Background/Purpose: Magnetic resonance imaging (MRI) has been used as a non-invasive tool to aid diagnosis and monitor disease activity in the idiopathic inflammatory myopathies (IIMs).…
Abstract Number: 390 • 2018 ACR/ARHP Annual Meeting
Severe Axial and Pelvifemoral Muscle Damage in Immune-Mediated Necrotizing Myopathy Evaluated By Whole-Body MRI
Océane Landon-Cardinal¹, Cedi Koumako², Giulia Hardouin³, Benjamin Granger³, Harmen Reyngoudt², Jean-Marc Boisserie², Aude Rigolet¹, Baptiste Hervier¹, Nicolas Champtiaux¹, Perrine Guillaume¹, Mathieu Vautier¹, Pierre Carlier², Olivier Benveniste¹ and Yves Allenbach¹, ¹Department of Internal Medicine and Clinical Immunology and Inflammation-Immunopathology-Biotherapy Department (I2B), Pitié-Salpêtrière University Hospital, Assistance Publique-Hôpitaux de Paris, East Paris Neuromuscular Diseases Reference Center, Paris, France, ²Laboratoire de RMN AIM & CEA, Centre d'Explorations Fonctionnelles, Institut de Myologie, Paris, France, ³Département de Biostatistiques, Santé Publique et Information Médicale, Groupe hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France
Background/Purpose: Immune-mediated necrotizing myopathies (IMNM) are a severe condition with early muscle damage attested by MRI of thigh muscles. Presence of damage in the other…
Abstract Number: 420 • 2018 ACR/ARHP Annual Meeting
Accelerated Knee Osteoarthritis Is Characterized By Destabilizing Meniscal Tears and Pre-Radiographic Structural Disease Burden
Jeffrey B. Driban¹, Julie Davis², Bing Lu³, Lori Lyn Price^4,5, Robert J. Ward⁶, James MacKay⁷, Charles B. Eaton⁸, Grace H. Lo⁹, Mary Barbe¹⁰, Ming Zhang¹¹, Jincheng Pang¹², Alina Stout¹³, Matthew Harkey¹³ and Timothy E. McAlindon¹⁴, ¹Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, ²Rheumatology, Tufts Medical Center, BOSTON, MA, ³Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ⁶Radiology, Tufts Medical Center, Boston, MA, ⁷Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, ⁸Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁹Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ¹⁰Temple University School of Medicine, Philadelphia, PA, ¹¹Tufts Medical Center, Boston, MA, ¹²Electrical Engineering, Tufts University, Medford, MA, ¹³Rheumatology, Tufts Medical Center, Boston, MA, ¹⁴Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: A subset of adults who develop knee osteoarthritis (KOA) quickly progress from no radiographic disease to advanced-stage disease often in ≤12 months. Adults with…

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