Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1171 • 2019 ACR/ARP Annual Meeting
Evidence of Subclinical Joint Inflammation of Hands by Magnetic Resonance Imaging in Patients with Psoriatic Arthritis in Minimal Disease Activity – Interim Analysis
Victoria Furer¹, Ari Polachek ², Liran Mendel ¹, David Levartovsky ³, Jonathan Wollman ⁴, Valerie Aloush ⁵, Ilana Kaufman ⁶, Hagit Sarbagil-Maman ⁷, Sara Borok ⁶, Mark Berman ⁶, Adi Broyde ⁶, Yael Lahat ¹, Mirna Zureik ¹, Sharon Nevo ¹, Daphna Paran ⁶, Iris Eshed ⁸ and Ori Elkayam ⁶, ¹Sourasky Medical Center, Tel-Aviv, Israel, ²Tel-Aviv Sourasky medical center, Tel Aviv, Israel, ³Sourasky medical center, Tel Aviv, Israel, ⁴Sourasky Medical Center, Herzelia, Israel, ⁵Tel Aviv Sourasky medical center, Tel Aviv, ⁶Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁷Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, ⁸Sheba Medical Center, Tel Aviv, Israel
Background/Purpose: Subclinical inflammatory lesions detected by MRI are prevalent in hand joints of patients with cutaneous psoriasis (1). Yet, it is unknown whether these inflammatory…
Abstract Number: 2213 • 2019 ACR/ARP Annual Meeting
Evaluation of Factors Associated with Bone Structure in an SLE Cohort Measured by Clinical 3T MRI and DEXA
Amit Saxena¹, Peter Izmirly ², Jill Buyon ², Stephen Honig ², Xiaoliu Zhang ³, Punam Saha ⁴, H. Michael Belmont ⁵ and Gregory Chang ², ¹New York University School of Medicine, New York, NY, ²NYU School of Medicine, New York, ³University of Iowa, Iowa City, ⁴University of Iowa Healthcare, Iowa City, ⁵New York University School of Medicine, Ney York
Background/Purpose: Osteoporosis and bone fractures are a frequent cause of morbidity in systemic lupus erythematosus (SLE), and are felt to be related both to disease…
Abstract Number: 1173 • 2019 ACR/ARP Annual Meeting
Magnetic Resonance Imaging in Patients in Clinical Remission: Tenosynovitis and Osteitis Are Independent Predictors of Radiographic and MRI Damage Progression
Signe Møller-Bisgaard¹, Kim Hørslev-Petersen ², Bo Ejbjerg ³, Merete Lund Hetland ⁴, Lykke Midtbøll Ørnbjerg ¹, Daniel Glinatsi ¹, Jakob Møller ⁵, Mikael Boesen ⁶, Kristian Stengaard-Pedersen ⁷, Ole Rintek Madsen ⁸, Bente Jensen ⁹, Jan Alexander Villadsen ¹⁰, Ellen-Margrethe Hauge ⁷, Philip Bennett ¹¹, Oliver Hendricks ¹², Karsten Asmussen ⁹, Marcin Kowalski ¹³, Hanne Lindegaard ¹⁴, Henning Bliddal ¹⁵, Niels Steen Krogh ¹⁶, Torkell Ellingsen ¹⁷, Agnete Nielsen ¹⁸, Lone Balding ⁵, Anne Grethe Jurik ¹⁹, Henrik Thomsen ⁵ and Mikkel Østergaard ²⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark, Copenhagen, Denmark, ²Department of Rheumatology, King Christian X’s Hospital for Rheumatic Diseases Graasten, Denmark, Graasten, Denmark, ³Department of Rheumatology, Zealand University Hospital, Køge, Denmark, Køge, Denmark, ⁴DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ⁵Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark, ⁶Department of Radiology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, ⁷Department of Rheumatology, Department of Clinical Medicine, Aarhus University Hospital, Aarhus University, Aarhus, Denmark, Aarhus, Denmark, ⁸Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ⁹Department of Rheumatology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, ¹⁰Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, ¹¹Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte, Hellerup, Denmark, Copenhagen, Denmark, ¹²Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, Sønderborg, Denmark, ¹³Department of Rheumatology, Hjørring Hospital, Hjørring, Denmark, Hjørring, Denmark, ¹⁴Department of Rheumatology, Odense University Hospital, Odense, Denmark, Odense, Denmark, ¹⁵The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, ¹⁶Zitelab / DANBIO, Copenhagen, Denmark, ¹⁷Department of Rheumatology, Odense University Hospital, Denmark, Odense, Syddanmark, Denmark, ¹⁸Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, ¹⁹Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, ²⁰Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Progression of structural joint damage develops in 20-30 % of patients with rheumatoid arthritis (RA) in clinical remission1. Known predictors of structural damage progression…
Abstract Number: 2335 • 2019 ACR/ARP Annual Meeting
Prediction of Myocardial Fibrosis in Rheumatoid Arthritis Assessed by Cardiac Magnetic Resonance Imaging Using Artificial Neural Networks Models
Hitomi Kobayashi¹, Isamu Yokoe ², Yasuyuki Kobayashi ³, Eichi Takaya ⁴, Atsuma Nishiwaki ¹, Kaita Sugiyama ¹, Noboru Kitamura ¹, Masaki Haraoka ³ and Masami Takei ¹, ¹Nihon University School of Medicine, Tokyo, Japan, ²Kyoundo Hospital, Tokyo, Japan, ³St.Marianna University School of Medicine, Kawasaki, Japan, ⁴Graduate School, Keio University, Tokyo, Japan
Background/Purpose: Cardiac involvements cause of morbidity and mortality globally in rheumatoid arthritis (RA). Myocardial dysfunction may arise from a number of distinct processes, including myocardial…
Abstract Number: 1175 • 2019 ACR/ARP Annual Meeting
Periarticular Inflammation and Bone Marrow Oedema Are Important in the Evaluation of Enthesitis on MRI in Patients with Peripheral and Axial SpA
Xenofon Baraliakos¹, Philipp Sewerin ², Eugenio de Miguel ³, Christine Kleinmond ⁴, Ankita Shekhawat ⁵, Annette Wiedon ⁶ and Frank Behrens ⁷, ¹Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, ²Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, ³Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ⁴ClinProject GmbH, Eurasburg, Germany, ⁵Novartis Healthcare Pvt. Ltd., Hyderabad, India, ⁶Novartis Pharma GmbH, Nürnberg, Germany, ⁷CIRI/Rheumatology and Fraunhofer TMP, Goethe-University, Frankfurt, Germany
Background/Purpose: Enthesitis is a hallmark feature of Spondyloarthritis (SpA), and frequently localizes at the Achilles tendon1. Enthesitis is predominantly measured with clinical scores like Leeds…
Abstract Number: 2728 • 2019 ACR/ARP Annual Meeting
Efficacy and Safety of Upadacitinib in a Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 2/3 Clinical Study of Patients with Active Ankylosing Spondylitis
Désirée van der Heijde¹, In-Ho Song ², Aileen Pangan ³, Atul Deodhar ⁴, Filip Van den Bosch ⁵, Walter P. Maksymowych ⁶, Tae-Hwan Kim ⁷, Mitsumasa Kishimoto ⁸, Andrea Everding ⁹, Yunxia Sui ¹⁰, Xin Wang ¹⁰, Alvina D. Chu ¹⁰ and Joachim Sieper ¹¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, ³AbbVie Inc., North Chicago, ⁴Oregon Health & Science University, Portland, OR, ⁵Ghent University Hospital, Ghent, Belgium, ⁶University of Alberta/CARE ARTHRITIS, Edmonton, AB, Canada, ⁷Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ⁸Immuno-Rheumatology Center, St. Luke’s International Hospital, Tokyo, Japan, ⁹HRF Hamburger Rheuma Forschungszentrum, Hamburg, Germany, ¹⁰AbbVie Inc., Chicago, ¹¹Charité Universitätsmedizin Berlin, Germany, Berlin, Germany
Background/Purpose: Patients (pts) with ankylosing spondylitis (AS) who have an inadequate response/contraindication to NSAIDs have limited treatment options other than biologics. The Janus kinase (JAK)…
Abstract Number: 1179 • 2019 ACR/ARP Annual Meeting
Resting-State Functional Connectivity of Pain Processing Brain Region Associated with Therapeutic Response to Biologics in Rheumatoid Arthritis and Spondyloarthritis
Nobuya Abe¹, Yuichiro Fujieda ¹, Kuniyuki Asou ¹, Kohei Karino ², Michihito Kono ³, Hisashi Narita ⁴, Masaru Kato ¹, Khin Tha ⁵, Kenji Oku ¹, Olga Amengual ¹, Shinsuke Yasuda ¹ and Tatsuya Atsumi ⁶, ¹Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ²Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ³Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, ⁴Department of Psychiatry, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ⁵Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, ⁶Hokkaido University, Sapporo, Japan
Background/Purpose: Background/Purpose: Discriminating inflammatory pain from non-inflammatory pain is critical to determine therapeutic strategy in inflammatory arthritis (IA) such as rheumatoid arthritis (RA) and spondyloarthritis…
Abstract Number: 2799 • 2019 ACR/ARP Annual Meeting
Does Early Anterior Cruciate Ligament Reconstruction Prevent Further Meniscal Damage? Secondary Analysis of a Randomized Controlled Trial
Barbara Snoeker ¹, Frank Roemer ², Aleksandra Turkiewicz ¹, Stefan Lohmander ³, Richard Frobell ¹ and Martin Englund¹, ¹Lund University, Lund, Sweden, ²University of Erlangen-Nuremberg, Erlangen, Germany, ³Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden, Lund, Sweden
Background/Purpose: It has been suggested that recurrent instability episodes in a non-reconstructed anterior cruciate ligament (ACL) injured knee increase the risk for an incident meniscal…
Abstract Number: 1187 • 2019 ACR/ARP Annual Meeting
Delayed Gadolinium-enhanced MR Imaging of Cartilage – A Pilot Study to Measure the Effect of Adalimumab Plus MTX versus Placebo Plus MTX on Cartilage in Early RA Patients (CAR-ERA-Study)
Philipp Sewerin¹, Miriam Frenken ², Ralph Brinks ³, Christoph Schleich ², Daniel Benjamin Abrar ², Stefan Vordenbaeumen ⁴, Ruben Sengewein ⁵, Jutta Richter ⁶, Matthias Schneider ⁷ and Benedikt Ostendorf ⁴, ¹Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, ²Institute for Diagnostic and Interventional Radiology, UKD, Heinrich Heine University, Duesseldorf, Germany, ³Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, ⁴Policlinic and Hiller Research Unit of Rheumatology, UKD, Heinrich Heine University, Duesseldorf, Germany, ⁵Policlinic and Hiller Research Unit of Rheumatology,, Duesseldorf, Germany, ⁶Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, Nordrhein-Westfalen, Germany, ⁷Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany
Background/Purpose: The purpose of this longitudinal study is to compare the effect of Adalimumab plus Methotrexate (MTX) versus MTX monotherapy on glycosaminoglycan content (GAG) in…
Abstract Number: 280 • 2019 ACR/ARP Annual Meeting
Ultrasound versus Conventional Treat-To-Target Strategies in Early Rheumatoid Arthritis: Magnetic Resonance Imaging Outcome Data from a 2-year Randomized Controlled Strategy Trial
Ulf Sundin¹, Anna-Birgitte Aga ², Øivind Skare ³, Lena Nordberg ³, Till Uhlig ⁴, Hilde Hammer ³, Désirée van der Heijde ⁵, Tore Kvien ⁴, Siri Lillegraven ⁶ and Espen Haavardsholm ⁴, ¹Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Norway. University of Oslo, Oslo, Norway, Oslo, Oslo, Norway, ²Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Oslo, Norway, ³Diakonhjemmet Hospital, Department of Rheumatology, Oslo, Norway, ⁴Diakonhjemmet Hospital, Dept. of Rheumatology / University of Oslo, Faculty of Medicine, Oslo, Norway, ⁵Leiden University Medical Center, Leiden, Netherlands, ⁶Diakonhjemmet Hospital, Dept. of Rheumatology, Oslo, Norway
Background/Purpose: It has been debated whether treatment outcomes in early RA would be improved by targeting imaging remission, assessed by ultrasound or MRI, in addition…
Abstract Number: 1299 • 2019 ACR/ARP Annual Meeting
Clinical Significance of Magnetic Resonance Imaging Derived Femur Bone Shape in Young Adults
Minh-Tu Vo ¹, Michael Bowes ², Alison Venn ³, Flavia Cicuttini ⁴, Lyn March ⁵, Terence Dwyer ⁶, Tao Meng ³, Marita Cross ⁵, Graeme Jones ⁷, Saliu Balogun ¹, Changhai Ding ⁷ and Benny Antony⁷, ¹University of Tasmania, Hobart, Tasmania, Australia, ²Imorphics, Manchester, England, United Kingdom, ³University of Tasmania, Hobart, Australia, ⁴Monash University, Melbourne, Australia, ⁵University of Sydney, Sydney, Australia, ⁶University of Oxford, Oxford, United Kingdom, ⁷Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: The femur bone shape derived from magnetic resonance imaging (MRI) of the knee is associated with the incidence and progression of knee osteoarthritis (OA),…
Abstract Number: L05 • 2018 ACR/ARHP Annual Meeting
Treatment-Naïve, Early Rheumatoid Arthritis Patients Demonstrate Reversible Abnormalities of Vascular Function on Cardiac MRI with RA Therapy with Preliminary Suggestion of Greater Improvement with Anti-TNF Compared to MTX/Conventional Therapy – a First, RCT Derived Longitudinal Study
Maya H. Buch¹, Bara Erhayiem², Graham Fent², Paul Baxter³, Elizabeth M.A. Hensor⁴, Adam McDiarmid², Peter Swoboda⁵, Ananth Kidambi², David Ripley², Pankaj Garg², Sarah Horton⁴, Raluca Bianca Dumitru⁴, Kamran Naraghi⁴, John Greenwood⁶, Paul Emery⁷, Sue Pavitt⁸ and Sven Plein², ¹Leeds Institute of Rheumatic & Musculosekeltal Medicine, University of Leeds & NIHR Biomedical Research Centre, Leeds, United Kingdom, ²Multidisciplinary Cardiovascular Research Centre, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ³Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Cardiovascular And Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ⁶Leeds Institute of Cardiovascular And Metabolic Medicinee, University of Leeds, Leeds, United Kingdom, ⁷University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ⁸Leeds School of Dentistry, University of Leeds, Leeds, United Kingdom
Background/Purpose: We previously reported abnormal cardiac MRI (CMR)-determined aortic stiffness in patients with early, treatment-naive RA1,2. We now report on whether this vascular stiffness is…
Abstract Number: 306 • 2018 ACR/ARHP Annual Meeting
The Role of Inflammation in the Evolution of MRI Erosions in the Feet of Patients with Early RA
Hanyan Zou¹, Karen A. Beattie², Saara Totterman³, George Ioannidis¹ and Maggie Larche^2,4, ¹McMaster University, Hamilton, ON, Canada, ²Medicine, McMaster University, Hamilton, ON, Canada, ³Qmetrics Technologies, Pittsford, NY, ⁴St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: Patients with aggressive RA develop early structural damage. As persistent inflammation is associated with bone erosions, assessing inflammatory activity may be key in treatment…
Abstract Number: 319 • 2018 ACR/ARHP Annual Meeting
Patterns of Muscle Oedema, Atrophy and Fatty Replacement in the Idiopathic Inflammatory Myopathies: A Single-Centre Retrospective Review of Magnetic Resonance Imaging Data
Jessica Day^1,2, Nicholas Bajic³, Sheridan Gentili⁴, Sandy Patel⁵ and Vidya Limaye⁶, ¹Rheumatology, Royal Adelaide Hospital, Adelaide, Australia, ²Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia, ³Dr Jones and Partners St Andrew's and Calvary Wakefield Hospitals, Adeliad, Australia, ⁴University of South Australia, Adelaide, Australia, ⁵Radiology, Royal Adelaide Hospital, Adelaide, Australia, ⁶Rheumatology, The Royal Adelaide Hospital, Adelaide, Australia
Background/Purpose: Magnetic resonance imaging (MRI) has been used as a non-invasive tool to aid diagnosis and monitor disease activity in the idiopathic inflammatory myopathies (IIMs).…
Abstract Number: 390 • 2018 ACR/ARHP Annual Meeting
Severe Axial and Pelvifemoral Muscle Damage in Immune-Mediated Necrotizing Myopathy Evaluated By Whole-Body MRI
Océane Landon-Cardinal¹, Cedi Koumako², Giulia Hardouin³, Benjamin Granger³, Harmen Reyngoudt², Jean-Marc Boisserie², Aude Rigolet¹, Baptiste Hervier¹, Nicolas Champtiaux¹, Perrine Guillaume¹, Mathieu Vautier¹, Pierre Carlier², Olivier Benveniste¹ and Yves Allenbach¹, ¹Department of Internal Medicine and Clinical Immunology and Inflammation-Immunopathology-Biotherapy Department (I2B), Pitié-Salpêtrière University Hospital, Assistance Publique-Hôpitaux de Paris, East Paris Neuromuscular Diseases Reference Center, Paris, France, ²Laboratoire de RMN AIM & CEA, Centre d'Explorations Fonctionnelles, Institut de Myologie, Paris, France, ³Département de Biostatistiques, Santé Publique et Information Médicale, Groupe hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France
Background/Purpose: Immune-mediated necrotizing myopathies (IMNM) are a severe condition with early muscle damage attested by MRI of thigh muscles. Presence of damage in the other…

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