Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1781 • 2016 ACR/ARHP Annual Meeting
Analysis of Influences of Various Factors on the Prognosis of Acute Confusional State of Diffuse Psychiatric/Neuropsychological Syndromes in Systemic Lupus Erythematosus
Gakuro Abe¹, Yoshiyuki Arinuma¹, Hirotoshi Kikuchi² and Shunsei Hirohata¹, ¹Kitasato University School of Medicine, Sagamihara, Japan, ²Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
Background/Purpose: Neuropsychiatric systemic lupus erythematosus (NPSLE), especially diffuse psychiatric/neuropsychological syndromes (diffuse NPSLE), is one of the most difficult complications of the disease. For the evaluation…
Abstract Number: 2317 • 2016 ACR/ARHP Annual Meeting
Preliminary Validation of a Magnetic Resonance Imaging-Based Inflammatory Scoring System in Adult Myositis
Nicolo Pipitone¹, Antonella Notarnicola^2,3, Arnaldo Scardapane⁴, Lucia Spaggiari⁵, Gabriele Levrini⁶, Florenzo Iannone⁷, Carlo Salvarani⁸, Giovanni Lapadula⁹, Ingrid E. Lundberg², Pierpaolo Pattacini¹⁰ and Giulio Zuccoli¹¹, ¹Rheumatology, Arcispedale S. M. Nuova, Reggio Emilia, Italy, ²Department of Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ³Rheumatology, Bari University, Bari, Italy, ⁴Radiology, University of Bari, Bari, Italy, ⁵Radiology, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁶Arcispedale S Maria Nuova, Reggio Emilia, Italy, ⁷Bari University, Rheumatology, Bari, Italy, ⁸Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, ⁹Rheumatology Unit, University of Bari, Bari, Italy, ¹⁰Radiology, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy, ¹¹Children's Hospital of Pittsburgh, Pittsburgh, PA
Background/Purpose: in patients with active myositis, magnetic resonance imaging (MRI) often demonstrates muscle edema thought to represent active inflammation. An MRI-based muscle inflammatory scoring system…
Abstract Number: 2367 • 2016 ACR/ARHP Annual Meeting
Association Between MRI-Detected Osteophytes and Changes in Knee Pain and Structures in Older Adults: A Population Based Cohort Study
Zhaohua Zhu¹, Laura Laslett², Xingzhong Jin³, Weiyu Han¹, Benny Samuel Eathakkattu Antony⁴, Xia Wang⁵, Flavia M Cicuttini⁶, Graeme Jones^7,8 and Changhai Ding⁷, ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ³Menzies institute for Medical Research, University of Tasmania, Hobart, Australia, ⁴Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ⁵Menzies institute for medical research, University of Tasmania, Hobart, Australia, ⁶Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia, ⁷Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁸Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia
Background/Purpose: Osteophyte (OP) formation is one of the clinical features of osteoarthritis (OA), so early detection of OP formation can be of diagnostic value. OP…
Abstract Number: 3090 • 2016 ACR/ARHP Annual Meeting
Inflammation Detected with Modern Sensitive MRI Analysis Demonstrates That Therapeutic Response As Early As One Month Predicts 12-Month Radiographic Progression: Data from a Study Using Tofacitinib and Methotrexate in Early RA
Philip G. Conaghan¹, Michael A Bowes², Mikkel Østergaard³, Gwenael Guillard², Douglass Chapman⁴, Amy Stein⁵, John Andrews⁴, Zhiyong Xie⁶, Andrew Koenig⁷, Koshika Soma⁴ and Bethanie Wilkinson⁶, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom, ³Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Pfizer Inc, New York, NY, ⁵Biostatistics, Quintiles, Morrisville, NC, ⁶Pfizer Inc, Groton, CT, ⁷Pfizer Inc, Collegeville, PA
Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. A novel automated quantification method for RA MRI-detected pathology using statistical shape…
Abstract Number: 3158 • 2016 ACR/ARHP Annual Meeting
What Predicts Absence of Spinal Damage in Patients with Spondyloarthritis after Prolonged Follow up?
Walter Maksymowych¹, Stephanie Wichuk¹, Praveena Chiowchanwisawakit², Robert G Lambert³ and Susanne J Pedersen⁴, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Medicine, Mahidol University, Bangkok, Thailand, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Rheumatology, Copenhagen University Hospitals, Copenhagen, Denmark
Background/Purpose: After 20 years of follow up the majority of patients with aspondyloarthritis (SpA) have developed new bone in the spine although disease may remain…
Abstract Number: 3060 • 2015 ACR/ARHP Annual Meeting
The Assessment of Disease Activity in Takayasu Arteritis; Six Years Experience from a Single Center
Handan Yarkan¹, Sedanur Karaman², Pinar Cetin¹, Servet Akar³, Aytac Gulcu⁴, Ahmet Yigit Goktay⁴, Gercek Can¹, Merih Birlik¹, Nurullah Akkoc⁵ and Fatos Onen¹, ¹Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ²Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ³Department of Internal Medicine, Division of Rheumatology, Izmir Katip Celebi University School of Medicine, Izmir, Turkey, ⁴Radiology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ⁵Department of Rheumatology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey
Background/Purpose: The aim of this study is to analyze the activity parameters that affect the physicians global opinion (PGO) in TA. Methods: The data of…
Abstract Number: 296 • 2015 ACR/ARHP Annual Meeting
Different Patterns of Involvement of Thigh Muscles in Dermatomyositis and Polymyositis Using Fat-Suppressed Magnetic Resonance Sequences
Nicolo Pipitone¹, Antonella Notarnicola², Lucia Spaggiari³, Gabriele Levrini⁴, Arnaldo Scardapane⁵, Florenzo Iannone⁶, Giovanni Lapadula⁶, Giulio Zuccoli⁷ and Carlo Salvarani⁸, ¹Unità di Reumatologia, Reggio Emilia, Arcispedale Santa Maria Nuova, Bari, Italy, ²Karolinska Hospital, Rheumatology Unit, Stockholm, Sweden, ³Radiology, Arcispedale S Maria Nuova, Reggio Emilia, Italy, ⁴Arcispedale S Maria Nuova, Reggio Emilia, Italy, ⁵Radiology, University of Bari, Bari, Italy, ⁶Bari University, Rheumatology, Bari, Italy, ⁷Children's Hospital of Pittsburgh, Pittsburgh, PA, ⁸Rheumatology, Arcispedale S.Maria Nuova, Reggio Emilia, Italy
Background/Purpose: MRI is often used to evaluate muscle inflammation in myositis. Muscle edema on fat-suppressed (short tau inversion recovery, STIR) sequences is thought to represent…
Abstract Number: 3084 • 2015 ACR/ARHP Annual Meeting
Progression of Lupus Pathology Is Correlative with Cardiac Magnetic Resonance Imaging Abnormalities, Diminished Function, and Inflammatory Histopathology in an Animal Model
Nicholas Young¹, Jeffrey Hampton¹, Saba Aqel¹, Jessica Pyles², Anna Bratasz², Anuradha Kalyanasundaram³, Wael N. Jarjour⁴ and Stacy P. Ardoin⁵, ¹Immunology and Rheumatology, The Ohio State University Medical Center, Columbus, OH, ²Small Animal Imaging Core, The Ohio State University Medical Center, Columbus, OH, ³Physiology and Cell Biology, The Ohio State University Medical Center, Columbus, OH, ⁴Department of Internal Medicine, Division of Immunology and Rheumatology, The Ohio State University Medical Center, Columbus, OH, ⁵Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease causing inflammation throughout the body and cardiovascular involvement is a significant contributor to morbidity and mortality…
Abstract Number: 297 • 2015 ACR/ARHP Annual Meeting
How Useful Is Magnetic Resonance Imaging (MRI) in Monitoring Patients with Myositis?
Nicolo Pipitone¹, Antonella Notarnicola², Arnaldo Scardapane³, Gabriele Levrini⁴, Lucia Spaggiari⁵, Florenzo Iannone⁶, Giovanni Lapadula⁶, Giulio Zuccoli⁷ and Carlo Salvarani⁸, ¹Unità di Reumatologia, Reggio Emilia, Arcispedale Santa Maria Nuova, Bari, Italy, ²Karolinska Hospital, Rheumatology Unit, Stockholm, Sweden, ³Radiology, University of Bari, Bari, Italy, ⁴Arcispedale S Maria Nuova, Reggio Emilia, Italy, ⁵Radiology, Arcispedale S Maria Nuova, Reggio Emilia, Italy, ⁶Bari University, Rheumatology, Bari, Italy, ⁷Children's Hospital of Pittsburgh, Pittsburgh, PA, ⁸Rheumatology, Arcispedale S.Maria Nuova, Reggio Emilia, Italy
Background/Purpose: MRI is commonly used to assess muscle inflammation in myositis. Muscle edema on fat-suppressed sequences is thought to reflect active inflammation. However, it is…
Abstract Number: 3125 • 2015 ACR/ARHP Annual Meeting
White Matter Magnetization Transfer Ratio Histogram Peak Height Helps Identifying Inflammatory Neuropsychiatric Systemic Lupus Erythematosus
César Magro Checa¹, Ece Ercan², Bart J Emmer³, Ron Wolterbeek⁴, Itamar Ronen², Mark A. Van Buchem², T. W. J. Huizinga⁵ and Gerda M. Steup-Beekman⁵, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Radiology, Erasmus Medical Center, Rotterdam, Netherlands, ⁴Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Magnetization transfer ratio (MTR) can be used to detect microstructural cerebral changes in normal-appearing brain tissue of neuropsychiatric systemic lupus erythematosus (NPSLE) patients. Our…
Abstract Number: 313 • 2015 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging Outcomes Using an Intra-Articular Injection (SM04690) in the Treatment of Osteoarthritis of the Knee: Interim, Exploratory Analysis of Results from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study
Yusuf Yazici¹, Sharmila Majumdar², Timothy E. McAlindon³, Roy Fleischmann⁴, Allan Gibofsky⁵, Marc C. Hochberg⁶, Christopher J. Swearingen¹, Anita DiFrancesco¹, Jeyanesh R. S. Tambiah¹, John Hood¹ and Nancy E. Lane⁷, ¹Samumed, San Diego, CA, ²Radiology, UCSF School of Medicine, San Francisco, CA, ³Rheumatology, Tufts Medical Center, Boston, MA, ⁴University of Texas Southwestern Medical Center, Dallas, TX, ⁵Weill Cornell Medical College and Hospital for Special Surgery, New York, NY, ⁶Department of Medicine, University of Maryland, Baltimore, MD, ⁷Center for Musculoskeletal Health, Univ of California at Davis, Sacramento, CA
Background/Purpose: Knee osteoarthritis (OA) is characterized by the destruction of articular cartilage, subchrondral bone alterations and varying degrees of synovitis. Current OA treatments are limited…
Abstract Number: 330 • 2015 ACR/ARHP Annual Meeting
Calf Muscle Adiposity Is Associated with Impaired Physical Performance in Knee OA
Michael Davison¹, Monica R. Maly², Jonathan D. Adachi³ and Karen A. Beattie⁴, ¹School of Medicine, McMaster University, Hamilton, ON, Canada, ²School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada, ³Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ⁴Medicine, McMaster University, Hamilton, ON, Canada
Background/Purpose: Knee osteoarthritis (OA) is a degenerative disease associated with significant muscle weakness and disability. Ectopic fat in the thigh, including intramuscular fat (intraMF; fat…
Abstract Number: 927 • 2015 ACR/ARHP Annual Meeting
Ultrasound Assessment of Heel Entheses in Spondyloarthritis Patients: A Comparative Study with Radiography and Magnetic Resonance Imaging
Rodrigo Aguila Maldonado¹, Santiago Ruta², Claudia Elizabeth Pena¹, Maria Laura Valuntas³, Gisela Pendón⁴, Dora Pereira⁴ and Mercedes Argentina García⁵, ¹Rheumatology Unit, HIGA San Martín La Plata, La Plata, Argentina, ²Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Servicio de Tomografía Computada y Resonancia Magnética, Sanatorio IPENSA, La Plata, Argentina, ⁴Hospital Ricardo Gutierrez, La Plata, La Plata, Argentina, ⁵Rheumatology Unit, HIGA San Martín, La Plata, Argentina
Background/Purpose: enthesitis is one of the main hallmarks of Spondyloarthritis (SpA), being heel entheses frequently involved. Different imaging modalities, such as conventional radiography (CR), ultrasound…
Abstract Number: 1300 • 2015 ACR/ARHP Annual Meeting
Comparison Between Semiquantitative and Quantitative Methods for the Assessment of Knee Synovitis Using Non-Enhanced and Gadolinium-Enhanced MRI
Michel D. Crema¹, Frank Roemer², Ling Li³, Laura B. Rosen⁴, Amanda Dudley⁵, Robert Alexander⁶ and Ali Guermazi⁷, ¹Department of Radiology, Boston University School of Medicine, Boston, MA, ²Radiology, Boston University School of Medicine, Boston, MA, ³Dana-Farber Cancer Institute, Boston, MA, ⁴AstraZeneca Neuroscience Innovative Medicines, Cambridge, MA, ⁵AstraZeneca Neuroscience Innovative Medicines, Cambridge, United Kingdom, ⁶Pfizer Neuroscience, Cambridge, MA, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: There is evidence that the presence of synovitis in knee osteoarthritis (OA) is clinically relevant since it is associated with pain and structural…
Abstract Number: 1301 • 2015 ACR/ARHP Annual Meeting
Pain Central Sensitization Assessed By Functional Magnetic Resonance Imaging in Patients with Knee Osteoarthritis
Jordi Monfort¹, Jesus Pujol², Marina Lopez³, Jone Llorente³, Gerard Martinez², Didac Macià², Francisco Montañés³, Miguel Angel Campillo³, Pedro Benito Ruiz⁴ and Joan Deus², ¹Rheumatology Department, Hospital del Mar, Barcelona, Spain, ²Magnetic Ressonance Imaging Unit, Barcelona, Spain, ³Rheumatology Department, Barcelona, Spain, ⁴Rheumatology Service, Hospital del Mar, Barcelona, Spain
Background/Purpose: An important aspect in chronic pain is central sensitization (CS) which involves increased responsiveness of the central neurons and it is clinically expressed like…

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