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Abstracts tagged "magnetic resonance imaging (MRI) and spondylarthritis"

  • Abstract Number: 2923 • 2018 ACR/ARHP Annual Meeting

    Is All MRI-SIJ Inflammation the Same? Gradient of Structural Damage with Increasing Cumulative Inflammation at the SIJ Quadrant Level in Axial Spondyloarthritis – 5-Year Data from the DESIR Cohort

    Santiago Rodrigues Manica1,2, Alexandre Sepriano1,3, Sofia Ramiro3,4, Robert B.M. Landewé5, Pascal Claudepierre6, Anna Moltó7, Maxime Dougados8, Miranda van Lunteren3 and Désirée van der Heijde9, 1CEDOC, NOVA Medical School, Lisbon, Portugal, 2Rheumatology, Hospital de Egas Moniz - Centro Hospitalar Lisboa Ocidental, EPE, Lisbon, Portugal, 3Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4Department of Rheumatology, Zuyderland Medical Center, Heerlen, Netherlands, 5Amsterdam Rheumatology & Clinical Immunology Center and Zuyderland Medical Center, Amsterdam; Heerlen, Netherlands, 6Hôpital Henri Mondor, Créteil, France, 7Paris Descartes University, Cochin Hospital, Paris, France, 8Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, 9Leiden University Medical Centre, Leiden, Netherlands

    Background/Purpose: Axial inflammation is a key feature in axial spondyloarthritis (axSpA). An (overall) definition of bone marrow oedema (BMO) on the MRI of the SIJ…
  • Abstract Number: 1830 • 2017 ACR/ARHP Annual Meeting

    Bone Marrow Edema in Sacroiliac Joints of Young Athletes Is Common and Shows Most Frequently in the Posterior Lower Ilium

    Ulrich Weber1, Anne Grethe Jurik2, Anna Zejden3, Ejnar Larsen4, Steen Hylgaard Jørgensen5, Kaspar Rufibach6, Christian Schioldan7 and Søren Schmidt-Olsen5, 1Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, 2Dept. of Radiology, Aarhus University Hospital, Aarhus, Denmark, 3Radiology, Aarhus University Hospital, Aarhus, Denmark, 4Radiology, North Denmark Regional Hospital, Hjørring, Denmark, 5Rheumatology and Sports Medicine, North Denmark Regional Hospital, Hjørring, Denmark, 6Biostatistics, F. Hoffmann-La Roche, Basel, Switzerland, Basel, Switzerland, 7Physiotherapy, Clinic Benefit, Frederikshavn, Denmark

    Background/Purpose: Low grade bone marrow edema (BME) was reported in the sacroiliac joints (SIJ) of up to 25% of healthy individuals and mechanical back pain…
  • Abstract Number: 67 • 2016 ACR/ARHP Annual Meeting

    Polymorphisms of ERAP1, IL23R and TRAILR1 Are Associated with MRI-Sacroiliitis in Early Axial Spondyloarthritis: Data from the French DESIR Cohort

    Cécile Luxembourger1, Yannick Degboé2, Alain Cantagrel3, Delphine Nigon4, Pascal Claudepierre5, Arnaud CONSTANTIN6 and Adeline Ruyssen-Witrand7, 1Rheumatology, Centre Hospitalier Universitaire, Toulouse Purpan, Toulouse, France, 2Rheumatology, Rheumatology Center, Purpan University Hospital, Toulouse, France, 3Rheumatology, INSERM CNRS UMR 1043, Paul Sabatier University Toulouse, Purpan Teaching Hospital, Toulouse, France, 4CHU Purpan, Toulouse, France, 5Hôpital Henri Mondor, Créteil, France, 6Rheumatology, CHU Purpan - Hôpital Pierre-Paul Riquet, Toulouse, France, 7Rheumatology Center, Purpan University Hospital, Toulouse, France

    Polymorphisms of ERAP1, IL23R and TRAILR1 are associated With MRI-Sacroiliitis in Early Axial Spondyloarthritis: Data from the French DESIR Cohort Background/Purpose: Spondyloarthritis (SpA) is a…
  • Abstract Number: 728 • 2016 ACR/ARHP Annual Meeting

    Correlation Between the Spinal MRI Findings and the Serum Level of DKK-1 in Patients with Spondyloarthritis Treated with TNF Antagonist

    Zheng Zhao, Gang Wang, Yanyan Wang, Jinshui Yang, Jian Zhu and Feng Huang, Rheumatology, Chinese PLA General Hospital, Beijing, China

    Background/Purpose : Recent prospective data suggest that spinal inflammatory damage in patients with ankylosing spondylitis will eventually convert into fat. In these complex inflammatory lesions,…
  • Abstract Number: 1295 • 2016 ACR/ARHP Annual Meeting

    The Prevalence of Inflammatory and Structural Lesions on MRI of the Sacroiliac Joints in Patients with Very Early Peripheral Spondyloarthritis

    Gaëlle Varkas1, Philippe Carron2, Heleen Cypers1, Dirk Elewaut1, Lennart Jans3 and Filip van Den Bosch4, 1Laboratory for Molecular Immunology and Inflammation, Department of Rheumatology, VIB, Ghent University and Ghent University Hospital, Ghent, Belgium, 2Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, 3Department of Radiology, Ghent University Hospital, Ghent, Belgium, 4Rheumatology, Ghent University Hospital, Ghent, Belgium

    Background/Purpose: To assess the prevalence of inflammatory and structural lesions on MRI of the sacroiliac joints (SIJ) in patients with peripheral spondyloarthritis (PSpA) in a…
  • Abstract Number: 1299 • 2016 ACR/ARHP Annual Meeting

    Can the 3D-Modified Dixon Methods Replace the Conventional Sacroiliac Joint Magnetic Resonance Imaging?

    Yoonah Song1, Seunghun Lee1 and Tae-Hwan Kim2, 1Department of Radiology, Hanyang University College of Medicine, Seoul Hospital, Seoul, South Korea, 2Department of Rheumatology, Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

    Can the 3D-modified Dixon Methods Replace the Conventional Sacroiliac Joint Magnetic Resonance Imaging?  ABSTRACT Background/Purpose: The purpose of our study was to assess the diagnostic…
  • Abstract Number: 3159 • 2016 ACR/ARHP Annual Meeting

    Validation of MRI Structural Lesions Using Computed Tomography in Patients with Axial Spondyloarthritis

    Robert G. Lambert1, Damien Loeuille2, Marie Raynal3, Jean Melchior2, Maria Antonietta D'Agostino4, Joel Paschke5 and Walter Maksymowych6, 1Radiology, University of Alberta, Edmonton, AB, Canada, 2Rheumatology, CHRU Vandoeuvre les Nancy, Nancy, France, 3Rheumatology, CHRU Nancy, Nancy, France, 4Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, 5CaRE Arthritis, Edmonton, AB, Canada, 6Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: MRI can detect both inflammatory and structural lesions in the sacroiliac joints (SIJ) of patients with axial SpA. However, standard MRI sequences do not…
  • Abstract Number: 1333 • 2015 ACR/ARHP Annual Meeting

    Assessment of Focal Fat Infiltration in Sacroiliac Joints in Patients with Spondyloarthritis By 1.5T Versus 3.0T Magnetic Resonance Imaging: Is the Field Strength Important to Contrast to Noise Ratios, Reproducibility and Total Scores?

    Jakob M. Møller1, Jelena Jankovic1, Mikkel Østergaard2, Inge Juul Sorensen3, Rene Poggenborg4, Ole Rintek Madsen5, Henrik S Thomsen1 and Susanne Juhl Pedersen6, 1Department of Radiology, Copenhagen University Hospital Herlev, Herlev, Denmark, 2Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Glostrup, Denmark, 3Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Glostrup, Denmark, 4Rheumatology, Copenhagen University Hospital at Gentofte, Gentofte, Denmark, 5Department of Rheumatology/C, Department of Rheumatology/C, Copenhagen University Hospital Gentofte, Hellerup, Denmark, 6Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark

    Background/Purpose: Reporting of focal fat infiltrations (FFI) in sacroiliac joints (SIJs) is becoming more important in patients with axial spondyloarthritis (SpA) since this lesion has…
  • Abstract Number: 1725 • 2015 ACR/ARHP Annual Meeting

    Reliable Evaluation of Structural Lesions of the Sacroiliac Joints on MRI in Patients with Axial Spondyloarthritis That Is Comparable to Evaluation of Inflammation Despite Minimal Calibration

    Rosaline van den Berg1, Susanne Juhl Pedersen2, Victoria Navarro-Compán3, Stephanie Wichuk4, Manouk de Hooge5, Robert G Lambert6, Désirée van der Heijde5 and Walter Maksymowych7, 1Leiden University Medical Center, Leiden, Netherlands, 2Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark, 3Rheumatology, University Hospital La Paz, Madrid, Spain, 4Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, 5Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 6Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, 7Medicine/Rheumatic Dis Unit, Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: There is growing recognition of the importance of structural lesions of the sacroiliac joints (SIJ) on MRI to the diagnostic evaluation of axial spondyloarthritis…
  • Abstract Number: 3211 • 2015 ACR/ARHP Annual Meeting

    Current Smoking, Its Intensity and Duration, Is Associated with Fat Metaplasia on MRI in Patients with Spondyloarthritis

    Walter Maksymowych1, Stephanie Wichuk1, Praveena Chiowchanwisawakit2, Zheng Zhao3, Donald Spady1, Barbara Conner-Spady1, Robert G Lambert4 and Susanne Juhl Pedersen5, 1Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, 2Rheumatology, Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand, 3Rheumatology, Chinese PLA General Hospital, Beijing, China, 4Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, 5Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark

    Background/Purpose:   Smoking has been associated with radiographic severity and progression in SpA although there is little understanding of the mechanism. Prospective MRI data indicates…
  • Abstract Number: 565 • 2014 ACR/ARHP Annual Meeting

    Effect of Certolizumab Pegol over 96 Weeks of Treatment on Inflammation of Spine and Sacroiliac Joints Measured By Magnetic Resonance Imaging in Patients with Axial Spondyloarthritis

    Jürgen Braun1, Walter P. Maksymowych2, Robert B. M. Landewé3, Christian Stach4, Owen Davies5, Tommi Nurminen4 and Desiree van der Heijde6, 1Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 2Department of Medicine, University of Alberta, Edmonton, AB, Canada, 3Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, 4UCB Pharma, Monheim, Germany, 5UCB Pharma, Slough, United Kingdom, 6Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose Previous results from RAPID-axSpA (NCT01087762) demonstrated that certolizumab pegol (CZP) reduced inflammation in the sacroiliac joints (SIJ) and spine, as assessed by Magnetic Resonance…
  • Abstract Number: 2586 • 2014 ACR/ARHP Annual Meeting

    Which Characteristics of Inflammatory Back Pain (CBP) Forecast the Presence of Sacroiliitis on Magnetic Resonance Imaging (MRI)? Results from the Esperanza Cohort

    Victoria Navarro-Compán1, Raquel Almodóvar González2, Azucena Hernández3, Emma Beltrán4, Eugenio De Miguel5, Robert B. M. Landewé6, Désirée van der Heijde7 and Pedro Zarco8, 1Rheumatology, University Hospital La Paz and Leiden University Medical Center, Madrid, Spain, 2Rheumatology Unit, Hospital Universitario Fundación Alcorcón, Madrid, Spain, 3Rheumatology, Hospital Virgen de la Salud, Toledo, Spain, 4University General Hospital of Valencia, Valencia, Spain, 5Rheumatology, University Hospital La Paz - IdiPaz, Madrid, Spain, 6Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, 7Leiden University Medical Center, Leiden, Netherlands, 8Rheumatology Department, Fundación Hospital Alcorcon, Alcorcon, Madrid, Spain

    Background/Purpose: CBP is often the starting point for a suspicion of axSpA. In the ASAS-criteria for axial SpA either MRI of the SI-joints or HLA-B27-testing…
  • Abstract Number: 1188 • 2014 ACR/ARHP Annual Meeting

    Reproducibility of Magnetic Resonance Imaging Diffusion Weighted Imaging in Axial Spondyloarthritis Patients and Healthy Subjects

    Jakob M. Møller1, Inge Juul Sorensen2, Mikkel Ostergaard3, Henrik Thomsen1, Ole Rintek Madsen4 and Susanne Juhl Pedersen5, 1Department of Radiology, Copenhagen University Hospital Herlev, Copenhagen, Denmark, 2Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Glostrup, Denmark, 3Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 4Rheumatology, Copenhagen University Hospital at Gentofte, Copenhagen, Denmark, 5Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark

    Reproducibility of Magnetic Resonance Diffusion Weighted Imaging In Axial Spondyloarthritis Patients and Healthy Subjects.Background/Purpose: Diffusion weighted imaging (DWI) is a magnetic resonance imaging (MRI) technique…
  • Abstract Number: 597 • 2014 ACR/ARHP Annual Meeting

    Inflammatory Burden in Recent-Onset Axial Spondyloarthritis

    Juan Jose Aznar Sánchez1, Raul Veroz Gonzalez1, Adela Gallego Flores1, Tamara Libertad Rodriguez Araya1, Piter José Cossio Jimenez2 and Eugenio Chamizo Carmona1, 1Rheumatology, Hospital de Mérida, Mérida, Spain, 2Hospital de Mérida, Mérida, Spain

    Background/Purpose Patients with Non-Radiographic Axial Spondylarthritis (non-Rx AxSpA) don't presnt with different clinical manifestations than patients with Ankilosing Spondylitis (AS), although the inflammatory burden measured…
  • Abstract Number: 2887 • 2013 ACR/ARHP Annual Meeting

    The Spondyloarthritis Research Consortium Of Canada MRI Sacroiliac Joint Structural Score:  A Method For Reliable Detection Of Structural Progression

    Walter P. Maksymowych1, Stephanie Wichuk1, Praveena Chiowchanwisawakit2, Robert GW Lambert3 and Susanne Juhl Pedersen4, 1Medicine, University of Alberta, Edmonton, AB, Canada, 2Mahidol University, Bangkok, Thailand, 3Radiology, University of Alberta, Edmonton, AB, Canada, 4Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark

    Background/Purpose:   With increasing focus on effective treatment intervention in early spondyloarthritis, there is an unmet need for reliable assessment of structural progression in the…
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