Abstracts tagged "macrophages and spondylarthritis"

Abstract Number: 1581 • 2017 ACR/ARHP Annual Meeting
Differential Involvement of Synovial and Entheseal Inflammation in Mediating Pathological IL23 Axis Signaling in Spondyloarthritis
Ed Purdue¹, Josselyn Galdamez¹, Madeline Epsten², Rima Abhyankar³, Kathleen Hoyt⁴, Michelle Lewis⁴, Devan Dove⁴, Jon Hill⁵, Alexander Klimowicz⁴, Gerald Nabozny⁶, Joseph Wahle⁴ and Lisa A. Mandl⁷, ¹Research, Hospital for Special Surgery, New York, NY, ²Rheumatology, Hospital for Special Surgery, New York, NY, ³Hospital for Special Surgery, New York, NY, ⁴Department of Immunology and respiratory discovery research, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, ⁵Department of Discovery research, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, ⁶[email protected], Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, ⁷Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY
Background/Purpose: Although accumulating evidence continues to point toward a critical role for IL23 signaling in spondyloarthritis (SpA), the cellular and molecular events involved, as well…

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