Abstract Number: 900 • ACR/ARHP Annual Meeting 2016
The Phenotype of Macrophages in the Inflamed Vascular Wall of Giant Cell Arteritis Resembles the Phenotype of Non-Classical Monocytes
Background/Purpose: Macrophages are critical tissue destructive cells in the immunopathology of patients with giant cell arteritis (GCA). Macrophage precursors, monocytes, can be subclassified in three…Abstract Number: 1122 • ACR/ARHP Annual Meeting 2016
Infliximab Suppresses the Monocyte Chemotaxis in Human TNF-Transgenic Mice
Background/Purpose: Macrophages in rheumatoid arthritis (RA) synovium produce high levels of inflammatory cytokines/chemokines and play the pivotal role in promoting inflammation and joint destruction. Treatment…Abstract Number: 2284 • ACR/ARHP Annual Meeting 2016
Differential Effect of MSU-Crystal Induced Inflammation on Macrophage Polarization
Background/Purpose: Gouty arthritis is a common inflammatory joint disease that arises in response to the deposition of monosodium urate (MSU) crystals in soft joints, periarticular…Abstract Number: 2179 • ACR/ARHP Annual Meeting 2014
The Monocyte-Phagocyte System in Gout: Enhanced Inflammasome Activity and Expansion of CD14++CD16+ Monocytes in Patients with Gout
Background/Purpose: The central role of the monocyte-macrophage system in gout has been highlighted during the last years. Macrophages initiate the inflammatory response to monosodium urate…Abstract Number: 1169 • ACR/ARHP Annual Meeting 2013
A Novel Pro-Inflammatory Signaling Pathway Regulated By Follistatin-Like Protein 1
Background/Purpose: Follistatin-like protein 1 (FSTL1) is a secreted glycoprotein produced mainly by cells of the mesenchymal lineage. The function of FSTL1 is still unclear, but…
ACR Meeting Abstracts