Macrophage and monocytes Archives - ACR Meeting Abstracts

Abstract Number: 1028 • ACR/ARHP Annual Meeting 2018
An Entheseal Innate Immune Cell Biological Basis for Differential Efficacy of PDE4 and IL-23 Pathway Blockade between Psoriatic Disease and Rheumatoid Arthritis
Charlie Bridgewood¹, Richard Cuthbert¹, Abdulla Watad², Tobias Russell¹, Timothy Palmer³, Robert Dunsmuir⁴, Almas Khan⁴, Abhay Rao⁴, Miriam Wittmann⁵ and Dennis McGonagle¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Department of Internal Medicine 'B', Sheba Medical Center, Ramat Gan, Ramat Gan, Israel, ³School of Pharmacy and Medical Sciences, University of Bradford, Bradford, United Kingdom, ⁴Department of Spinal Surgery, National Health Service, Leeds, United Kingdom, ⁵NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: Both IL-23 and phosphodiesterase (PDE) 4 inhibition are ineffective in RA but show efficacy in PsA-related synovitis despite similar cytokine and molecular profiles between…

Abstracts tagged "Macrophage and monocytes"