Abstracts tagged "Macrophage and lupus nephritis"

Abstract Number: 1771 • 2015 ACR/ARHP Annual Meeting
Blockade of Immune Complex-Mediated Glomerulonephritis By Highly Selective Inhibition of Bruton’s Tyrosine Kinase
Samantha Chalmers¹, Jessica Doerner², Todd Bosanac³, Sara Khalil³, Dustin Smith³, Christian Harcken³, Janice Dimock³, Evan Der², Leal Herlitz⁴, Deborah Webb³, Elise Seccareccia³, Jay Fine³, Elliott Klein³, Meera Ramanujam³ and Chaim Putterman⁵, ¹Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, ⁴Cleveland Clinic, Cleveland, OH, ⁵Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Renal disease with loss of organ function results in significant morbidity and mortality in SLE. In the kidneys of affected patients, autoantibody-containing immune complexes…

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Abstracts tagged "Macrophage and lupus nephritis"

Blockade of Immune Complex-Mediated Glomerulonephritis By Highly Selective Inhibition of Bruton’s Tyrosine Kinase