Abstracts tagged "macrophage activation syndrome and monoclonal antibodies"

Abstract Number: 752 • 2012 ACR/ARHP Annual Meeting
IFNg Production Is Intimately Associated with Clinical and Laboratory Features of CpG-Induced Secondary Hemophagocytic Lymphohistiocytosis (sHLH)/Macrophage Activating Syndrome (MAS) in Mice
Vanessa Buatois¹, Laurence Chatel¹, Laura Cons¹, Maureen Deehan¹, Cristina de Min², Marie Kosco-Vilbois¹ and Walter Ferlin¹, ¹NovImmune S.A., Geneva, Switzerland, ²Novimmmune S.A., Plan-Les-Ouates, Geneva, Switzerland
Background/Purpose: Repeated TLR9 stimulation with CpG DNA has been found to result in a sHLH/MAS-like disease in mice (1). CpG-administered mice present with cytopenia, anemia,…

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Abstracts tagged "macrophage activation syndrome and monoclonal antibodies"

IFNg Production Is Intimately Associated with Clinical and Laboratory Features of CpG-Induced Secondary Hemophagocytic Lymphohistiocytosis (sHLH)/Macrophage Activating Syndrome (MAS) in Mice