Abstracts tagged "Lymphocytes and methotrexate (MTX)"

Abstract Number: 2424 • 2017 ACR/ARHP Annual Meeting
CD8-Positive Lymphocytes in Biopsy Specimens Predict Spontaneous Regression of Lymphoproliferative Disorders in Patients with Rheumatoid Arthritis Treated with Methotrexate
Tomohiro Kameda¹, Hiroaki Dobashi¹, Masayuki Inoo², Ikuko Onishi², Noriyuki Kurata², Mikiya Kato¹, Atsushi Kondo¹, Risa Wakiya¹, Hiromi Shimada¹, Shusaku Nakashima¹, Miharu Izumikawa¹ and Norimitsu Kadowaki¹, ¹Internal Medicine Division of Hematology, Rheumatology, and Respiratory Medicine, Kagawa University, Kagawa, Japan, ²Utazu hospital, Kagawa, Japan
Background/Purpose: Patients with rheumatoid arthritis (RA) have a high risk of developing lymphoproliferative disorders (LPDs). LPDs that develop in patients treated with methotrexate (MTX) are…
Abstract Number: 2724 • 2015 ACR/ARHP Annual Meeting
Methotrexate Treatment Could Modulate the Abnormal CD4+T Lymphocyte Subset Distribution in NaÏve Rheumatoid Arthritis Patients
Cristina Bohórquez Heras¹, Lucía Ruiz Gutiérrez¹, Carolina Garcia Torrijos², Ana Turrión Nieves¹, Ana Pérez Gómez¹, Ana Sánchez Atrio¹, Eduardo Cuende¹, Atusa Movasat¹, Fernando Albarrán Hernández¹, Henry Moruno¹, M José León¹, David Diaz², Jorge Monserrat² and Melchor Álvarez de Mon^1,2, ¹University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology department, Alcalá de Henares, Madrid, Spain, ²Laboratory of Immune System Diseases, Department of Medicine, University of Alcalá, Alcalá de Henares, Madrid, Spain
Background/Purpose: Mechanisms regulating the chronic autoimmune response in rheumatoid arthritis (RA) are not well understood. However, activated T CD4+ play a pivotal role initiating and…
Abstract Number: 1398 • 2014 ACR/ARHP Annual Meeting
Spontaneous Regression of Methotrexate (MTX)-Related Lymphoproliferative Disorder Correlates with Lymphocyte Restoration after MTX Withdrawal
Shuntaro Saito¹, Yuko Kaneko¹, Katsuya Suzuki¹, Michihide Tokuhira² and Tsutomu Takeuchi¹, ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Department of Hematology., Saitama Medical Center, Saitama Medical University., Saitama, Japan
2013 > Five patients were given chemotherapy after the diagnosis of MTX-LPD, so we analyzed the remaining 27 patients in this study. Baseline characteristics of…