Abstracts tagged "lupus nephritis and viruses"

Abstract Number: 1067 • ACR/ARHP Annual Meeting 2012
Spontaneous Aggregation of the Anti-Viral Mavs Protein in Certain Systemic Lupus Erythematosus Patients May Explain Excessive Type I Interferon Production
Philip L. Cohen¹ and Wen-Hai Shao², ¹Rheumatology, Temple University, Philadelphia, PA, ²Medicine, Temple University School of Medicine, Philadelphia, PA
Background/Purpose: Patients with systemic lupus (SLE) often have increased type I interferon levels (IFN-I) and activation of IFN-inducible genes (IFN signature). The mitochondrial adaptor protein…