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Abstracts tagged "Lupus nephritis and treatment"

  • Abstract Number: 2666 • ACR/ARHP Annual Meeting 2018

    Trends in Treatment of Systemic Lupus Erythematosus and Lupus Nephritis: 2006-2016

    Ali Duarte-Garcia1, Cynthia S. Crowson2, Rozalina McCoy1, Stephanie Schilz3, Holly Van Houten4, Lindsey Sangaralingham4, Vaidehi R. Chowdhary5, Shreyasee Amin6, Kenneth J. Warrington7, Eric L. Matteson8 and Nilay Shah9, 1Mayo Clinic College of Medicine and Science, Rochester, MN, 2Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 3Health Sciences Research, Mayo Clinic, Rochester, MN, 4Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, 5Internal Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, 6Rheumatology, Mayo Clinic, Rochester, MN, 7Rheumatology, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN, 8Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, 9Health Care Policy and Research, Mayo Clinic College of Medicine and Science, Rochester, MN

     Background/Purpose: Glucocorticoids, anti-malarials and conventional immunosuppressive agents have been the mainstay of therapy for systemic lupus erythematosus (SLE) and lupus nephritis (LN); more recently biologic…
  • Abstract Number: 670 • ACR/ARHP Annual Meeting 2017

    Membrane Attack Complex (MAC) Deposition in Lupus Nephritis Is Associated with Hypertension and Poor Clinical Response to Treatment

    Shudan Wang1, Ming Wu2, Luis Chiriboga3, Briana Zeck4 and H. Michael Belmont5, 1Department of Medicine, Division of Rheumatology, New York University School Medicine, New York City, NY, 2New York University School of Medicine, New York, NY, 3Pathology, New York University School Medicine, New York, NY, 4Pathology, New York University School Medicine, New York City, NY, 5Medicine, New York University School of Medicine, New York, NY

    Background/Purpose: LN is characterized by deposition of immune complexes in the kidney. Activation of the classical complement pathway by dsDNA is believed to play a…
  • Abstract Number: 885 • ACR/ARHP Annual Meeting 2017

    48-Week Complete Remission By Ethnic, Sex and Age Subgroups in Patients with Active Lupus Nephritis Treated with Voclosporin

    David Wofsy1, David A. Isenberg2, Frédéric A. Houssiau3, Mary Anne Dooley4, Neil Solomons5 and Simrat Randhawa6, 1Rheumatology, UCSF, San Francisco, CA, 2Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, 3Rheumatology, Pôle de Maladies Rhumatismales, Université catholique de Louvain, Brussels, Belgium, 4UNC Kidney Centre, Chapel Hill, NC, 5Aurinia Pharmaceuticals Inc., Victoria, BC, Canada, 6Medical Affairs, Aurinia Pharmaceuticals, Victoria, BC, Canada

    Background/Purpose: Voclosporin (VCS) is a novel CNI with a favorable metabolic profile, no observed effect on electrolytes, and a predictable dose response potentially eliminating the…
  • Abstract Number: 988 • ACR/ARHP Annual Meeting 2015

    Factors Associated with Renal Remission, Relapse and Long-Term Renal Function Decline in Lupus Nephritis Treated with Combined Prednisolone and Mycophenolate Mofetil (MMF) or Tacrolimus (Tac)

    Chi Chiu Mok1, Ling Yin Ho2, Chi Hung To3 and Kar Li Chan1, 1Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, 2Dept of Medicine, Tuen Mun Hospital, Hong Kong SAR, Hong Kong, 3Medicine, Pok Oi Hospital, Hong Kong, Hong Kong

    Background/Purpose: To study the factors associated with renal remission, relapse and renal function decline in patients with lupus nephritis treated with combined steroid and MMF or…

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