Abstracts tagged "lupus nephritis and signal transduction"

Abstract Number: 1447 • 2012 ACR/ARHP Annual Meeting
A Synthetic Triterpenoid CDDO-Me Prevents and Reverses Murine Lupus Nephritis
Tianfu Wu¹, Yujin Ye¹, Mei Yan¹, Xin J. Zhou², Michael Andreef³ and Chandra Mohan¹, ¹Division of Rheumatology/Internal Medicine, University of Texas, Southwestern Medical Center at Dallas, Dallas, TX, ²Internal Medicine - Rheumatic Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, ³Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas M. D. Anderson Cancer Center, Houston, TX
Background/Purpose: Current treatment options for lupus are far from optimal. Previously, we have reported that PI3K/AKT/mTOR, MEK1/Erk1,2, p38, STAT3, STAT5, NF-κB, multiple Bcl-2 family members,…

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Abstracts tagged "lupus nephritis and signal transduction"

A Synthetic Triterpenoid CDDO-Me Prevents and Reverses Murine Lupus Nephritis