Abstracts tagged "lupus nephritis and Macrophage"

Abstract Number: 1784 • 2019 ACR/ARP Annual Meeting
Single Cell Analysis of Renal Myeloid Cells from NZB/WF1 Mice with Lupus Nephritis Reveals Multiple Subsets with Altered Functions
Rakesh Mishra ¹, Celine Berthier ², Heather Geiger ³, Weijia Zhang ⁴ and Anne Davidson⁵, ¹Feinstein Institute for Medical Research, manhasset, NY, ²University of Michigan, Ann Arbor, MI, ³New York Genome Center, New York, NY, ⁴Mount Sinai School of Medicine, New York, NY, ⁵Feinstein Institutes for Medical Research, Manhasset
Background/Purpose: Renal infiltration with macrophages and dendritic cells is associated with poor prognosis in humans with lupus nephritis (LN). However, the precise pathogenic and/or protective…