Abstracts tagged "Lupus and plasma cells"

Abstract Number: 549 • ACR/ARHP Annual Meeting 2013
Augmented Megakaryopoiesis Supports Accumulation Of Plasma Cells In Lupus-Prone Mice
Oliver Winter¹, Niels-Peter Becker², Stephanie Musiol², Katrin Moser³, Falk Hiepe⁴ and Rudolf A. Manz⁵, ¹Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany, ²Charité - University Medicine Berlin, Berlin, Germany, ³German Arthritis Research Center (DRFZ Berlin), Berlin, Germany, ⁴Rheumatology and Clinical Immunology, Charité University Hospital Berlin, Berlin, Germany, ⁵Institute for Systemic Inflammation Research (ISEF), University of Lübeck, Lübeck, Germany
Background/Purpose: Autoantibodies - secreted by short- and long-lived plasma cells in bone marrow and spleen - trigger the immune response, and immune complex deposits in…