Abstracts tagged "Lupus and pathogenesis"

Abstract Number: 644 • 2019 ACR/ARP Annual Meeting
Decreased HVEM Expression in Lupus Patients and Impact of HVEM Knockout Mouse Model of Lupus Suggest a Role for BTLA Signaling in Disease Pathogenesis
Andrew Vendel¹, Kimberly Griffiths ¹, Antje Rhode-Kurnow ², Eve Merriman ¹, Mark Daniels ¹, William Chang ¹ and Carl Ware ², ¹Lilly Biotechnology Center, San Diego, CA, ²Sanford Burnham Prebys Medical Research Institute, La Jolla, CA
Background/Purpose: B and T Lymphocyte Attenuator (BTLA; CD272) is an Ig superfamily member and part of a family of checkpoint receptors that negatively regulate immune…

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Abstracts tagged "Lupus and pathogenesis"

Decreased HVEM Expression in Lupus Patients and Impact of HVEM Knockout Mouse Model of Lupus Suggest a Role for BTLA Signaling in Disease Pathogenesis