Abstracts tagged "Lupus and neuropsychiatric disorders"

Abstract Number: 2095 • 2018 ACR/ARHP Annual Meeting
Neutralizing CXCL13 Attenuates Neuropsychiatric Disease in Lupus-Prone Mice
Michelle Huang¹, Ariel Stock² and Chaim Putterman³, ¹Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Despite the many lupus patients affected by neuropsychiatric signs and symptoms, the pathogenesis of neuropsychiatric disease in SLE remains unclear. MRL-lpr/lpr mice, a classic…
Abstract Number: 711 • 2017 ACR/ARHP Annual Meeting
Prevalence and Risk Factors of Depressive Disorders in Chinese Patients with Systemic Lupus Erythematosus (SLE)
Chi Chiu Mok¹, Yan Tung Lilian Lo², Chi Wai Cheng² and Kam Shan Poon², ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Psychiatry, Castle Peak Hospital, Hong Kong, Hong Kong
Background/Purpose: Depression is common in SLE but most previous studies utilized self-rated scales for evaluation. Formal diagnosis of depression was not established by psychiatric interviews.…
Abstract Number: 97 • 2017 Pediatric Rheumatology Symposium
Bortezomib is Efficacious in the Treatment of Refractory Neuropsychiatric SLE with Psychosis
Renee F Modica¹, Kathleen M Vazzana², Natalie Jane Shiff³, Akaluck Thatayatikom³ and Melissa E Elder¹, ¹Department of Pediatrics, University of Florida, Gainesville, FL, ²Pediatrics, University of Florida at Orlando Health Arnold Palmer Hospital for Children, Orlando, FL, ³Pediatrics, University of Florida, Gainesville, FL
Background/Purpose: Neuropsychiatric systemic lupus erythematosus (NPSLE) with psychosis is challenging to treat with refractory cases often requiring prolonged hospitalization due to significant functional impairment and…
Abstract Number: 2056 • 2016 ACR/ARHP Annual Meeting
Choroid Plexus Infiltrates in Lupus Model (MRL/lpr) Mice Represent Tertiary Lymphoid Structures, Shedding Light on the Immunological Mechanisms of Neuropsychiatric Lupus
Ariel Stock¹, Sivan Gelb², Ayal Ben-Zvi² and Chaim Putterman³, ¹Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, ²Hebrew University, Jerusalem, Israel, ³Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: MRL/lpr mice develop an overt neuropsychiatric phenotype including depression and cognitive dysfunction, similar to diffuse neuropsychiatric manifestations of human lupus. Additionally, MRL/lpr mice display…