Lupus and mouse model Archives - ACR Meeting Abstracts

Abstract Number: 1756 • ACR/ARHP Annual Meeting 2015
The Oxidative Burst Mediates Anti-Inflammatory Clearance of Dead Cells in a Mouse Model of SLE and Inflammatory Arthritis
Jonas Hahn¹, Deborah Kienhöfer¹, Luis Munoz¹, Martin Herrmann², Gerhard Krönke³, Rikard Holmdahl⁴, Georg Schett⁵ and Markus Hoffmann¹, ¹Medicine III, Rheumatology and Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Medicine III, Rheumatology and Immunology, University of Erlangen-Nuremberg, Osterreich, Germany, ³Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, ⁴Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden, ⁵Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: The production of reactive oxygen species (ROS) via the oxidative burst has recently been implicated in regulation of inflammation and protection from arthritis, multiple…
Abstract Number: 662 • ACR/ARHP Annual Meeting 2014
Interferon Regulatory Factor-5 Promotes Disease in the MRL/Lpr Mouse Model of Lupus
Amanda Watkins¹, Ramon Bonegio², Guneet Kochar¹, Gabriella Wilson¹, Bari Laskow¹, Christophe Richez¹, Ian Rifkin¹ and Kei Yasuda³, ¹Boston University School of Medicine, Boston, MA, ²Renal, Boston University School of Medicine, Boston, MA, ³Medicine, Boston University School of Medicine, Boston, MA
Background/Purpose Interferon regulatory factor 5 (IRF5) polymorphisms are strongly associated with an increased risk of developing Systemic Lupus Erythematosus (SLE). SLE is caused, in part,…

Abstracts tagged "Lupus and mouse model"

The Oxidative Burst Mediates Anti-Inflammatory Clearance of Dead Cells in a Mouse Model of SLE and Inflammatory Arthritis

Interferon Regulatory Factor-5 Promotes Disease in the MRL/Lpr Mouse Model of Lupus