Abstracts tagged "Lupus and environmental factors"

Abstract Number: 983 • 2017 ACR/ARHP Annual Meeting
Identifying Exposures to Chemicals in Patients with SLE – a Non-Targeted Exposome Approach Reveals Enrichment for Phthalates
Cristina Lanata¹, Thomas Lin², Maria Dall'Era¹, Jinoos Yazdany³, Patricia P. Katz¹, Laura Trupin³, Charles G. Helmick⁴, Roy Gerona⁵ and Lindsey A. Criswell¹, ¹Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ²Univeristy of California, San Francisco, SAN FRANCISCO, CA, ³Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ⁴Centers for Disease Control and Prevention, Atlanta, GA, ⁵Obstetrics and Gynecology, University of California, San Francisco, SAN FRANCISCO, CA
Background/Purpose: Environmental exposures may play a substantial role in the pathogenesis of SLE. The goal of this study is to characterize the serum levels of…
Abstract Number: 3080 • 2015 ACR/ARHP Annual Meeting
Histone H2AX Phosphorylation As a Measure of DNA Double Strand Breaks and a Marker of Environmental Stress and Disease Activity in Lupus
Rajaie Namas, Paul Renauer, Mikhail Ognenovski, Pei-Suen Tsou and Amr H. Sawalha, Division of Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: Studies suggested that defective or inefficient DNA double strand break (DSB) repair results in failure to preserve genomic integrity leading to apoptotic cell death,…
Abstract Number: 2540 • 2013 ACR/ARHP Annual Meeting
Serum Mercury Level and Disease Activity Of Systemic Lupus Erythematosus (SLE): A Case-Control Study
Chi Chiu Mok¹, Becky Fong¹ and Chris Wong², ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Biology, Baptist University Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Environmental contamination with mercury (Hg) is linked to autoimmune diseases. Exposure to low-dose non-organic mercury has been reported to exacerbate murine SLE. The aim of…

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