ACR Meeting Abstracts
Abstract Number: 25 • ACR/ARHP Annual Meeting 2017
Shinji Okitsu1, Melinda Genest1, Nuruddeen Lewis1, Evgeni Tzvetkov1, Yin Wu2, Andrew Bender1, Arnon Arazi3, Thomas Eisenhaure3, Edward Browne4, Alex Rolfe5, Jonathan Derry6, William Pendergraft III7, Nir Hacohen8, Julie DeMartino5 and Jaromir Vlach5, 1TIP Immunology, EMD Serono Research and Development Institute, Billerica, MA, 2TIP Immunology, EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 3Broad Institute, Cambridge, MA, 4Massachusetts General Hospital, Boston, MA, 5EMD Serono Research and Development Institute, Billerica, MA, 6Iris Bioconsulting, Bainbridge Island, WA, 7Kidney Center, University of North Carolina, Chapel Hill, NC, 8Harvard Medical School, Boston, MA
Background/Purpose: Antibodies are important in protection against pathogens, but also harbor the potential to cause autoimmune disease when directed against self-antigens. Systemic lupus erythematosus (SLE)…