Abstracts tagged "Lupus and autoantibodies"

Abstract Number: 684 • 2017 ACR/ARHP Annual Meeting
ANTI-RO52 KDa and ANTI-RO60 KDa Analysis in Systemic LUPUS Erythematous Patients to Detect ANTI-RO False-Negatives
Elena Grau Garcia¹, Inmaculada Chalmeta Verdejo¹, David Gimenez-Romero², Eztizen Labrador Sanchez¹, Merixell Fernandez Matilla³, Francisco Miguel Ortiz-Sanjuán¹, Carlos Feced Olmos¹, Nagore Fernandez-Llanio Cornella³, Karla Arevalo Ruales¹, Rosa Negueroles Albuixech¹, Jose Ivorra Cortes¹, Jorge Juan Fragio Gil¹, Isabel Martinez Cordellat¹, Roxana Gonzalez Mazario¹, Luis Gonzalez Puig¹, Cristina Alcañiz Escandell¹, Carmen Najera Herranz¹, Ines Canovas Olmos¹, Elvira Vicens Bernabeu¹, Jose Eloy Oller Rodriguez¹, Jose Antonio Castellano Cuesta³, Victoria Fornes Ferrer⁴, David Hervás Marín⁴, Marta De la Rubia Navarro¹ and Jose Andres Roman Ivorra¹, ¹Rheumatology Department. Hospital Universitario y Politecnico La Fe, Valencia, Spain, ²Physical-Chemistry Department, UV, Valencia, Spain, ³Rheumatology Section. Hospital Arnau de Vilanova, Valencia, Spain, ⁴Biostatistics Unit. IIS La Fe, Valencia, Spain
Background/Purpose: Systemic lupus erythematous (SLE) is an autoimmune disease characterized by immune system disruption with autoantibodies production. One of the upregulated autoantibodies is the specific…
Abstract Number: 1092 • 2016 ACR/ARHP Annual Meeting
Expansion of Age Associated B Cells in Murine Lupus Is Regulated By DEF6 and Its Homologue Swap-70
Michela Manni¹, Sanjay Gupta², Edd Ricker³, Yurii Chinenov⁴, Rolf Jessberger⁵ and Alessandra B. Pernis^2,6,7,8, ¹Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, NY, ²Autoimmunity & Inflammation Research Program, Hospital for Special Surgery, New York, NY, ³Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medical Sciences, New York, NY, ⁴Arthritis & Tissue Degeneration Program, Hospital for Special Surgery, New York, NY, ⁵Dresden University of Technology, Dresden, Dresden, Germany, ⁶Autoimmunity & Inflammation, Hospital for Special Surgery, New York, NY, ⁷David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY, ⁸Department of Medicine, Weill Cornell Medical College, New York, NY
Background/Purpose: Age-associated B cells (ABCs) are a novel B cell subset, which expresses CD11c and preferentially accumulates with age in female mice. Increased expansion of…
Abstract Number: 2803 • 2016 ACR/ARHP Annual Meeting
Comparison of Clinical and Serological Differences According to the Autoantibody Cluster in Women with Systemic Lupus Erythematosus: Results from the Korean Lupus Network (KORNET) Registry
Ji-Eun Kim¹, Dong-Jin Park², Ji-Hyoun Kang², Yi-Rang Yim¹, Jeong-Won Lee¹, Kyung-Eun Lee², Lihui Wen¹, Tae-Jong Kim³, Yong-Wook Park² and Shin-Seok Lee³, ¹Chonnam National University Medical School and Hospital, Gwangju, South Korea, ²Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, ³Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Korea, The Republic of
Background/Purpose: Individual autoantibodies are associated with the clinical features in patients with systemic lupus erythematosus (SLE). However, few studies have investigated differences in disease presentation…
Abstract Number: 2816 • 2016 ACR/ARHP Annual Meeting
Broad Autoantibody Profiling in Ethnically Diverse SLE Cohorts Reveals a Set of Conserved Autoantibodies That Are Correlated to a Type I Interferon Signature
Takahiro Sato, Matteo Cesaroni, Jessica Schreiter, Jarrat Jordan, Marc Chevrier and Jacqueline Benson, Estrela Lupus Venture, Janssen Research and Development, LLC., Spring House, PA
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease with a wide range of clinical manifestations. Production of autoantibodies is a hallmark of SLE and…
Abstract Number: 889 • 2013 ACR/ARHP Annual Meeting
Podocytes Take Up Adsdna Autoantibody Complexes
Anja Hillmann¹, Elisabeth Jung², Annika Engbers¹, Hedda Wardemann³, Annett M. Jacobi² and Thomas Pap⁴, ¹Institute of Experimental Musculoskeletal Medicine, University Hospital Münster, Münster, Germany, ²Rheumatology Internal Medicine D, University Hospital Münster, Münster, Germany, ³Max Planck Research Group Molecular Immunology, Max Planck Institute for Infection Biology, Berlin, Germany, ⁴Institute of Experimental Muskuloskeletal Medicine, University Hospital Münster, Münster, Germany
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease, resulting in inflammation and tissue damage in several organs. This autoimmune reaction is caused by autoantibodies,…

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